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Electronic health records (EHRs) contain patients' heterogeneous data that are collected from medical providers involved in the patient's care, including medical notes, clinical events, laboratory test results, symptoms, and diagnoses. In…

Artificial Intelligence · Computer Science 2024-11-12 Shuai Niu , Yunya Song , Qing Yin , Yike Guo , Xian Yang

Modeling user behavior sequences in recommender systems is essential for understanding user preferences over time, enabling personalized and accurate recommendations for improving user retention and enhancing business values. Despite its…

Information Retrieval · Computer Science 2025-02-18 Hui Lu , Zheng Chai , Yuchao Zheng , Zhe Chen , Deping Xie , Peng Xu , Xun Zhou , Di Wu

Sequential Recommender Systems (SRS) aim to predict users' next interaction based on their historical behaviors, while still facing the challenge of data sparsity. With the rapid advancement of Multimodal Large Language Models (MLLMs),…

Information Retrieval · Computer Science 2026-02-17 Mingyao Huang , Qidong Liu , Wenxuan Yang , Moranxin Wang , Yuqi Sun , Haiping Zhu , Feng Tian , Yan Chen

Accuracy and interpretability are two dominant features of successful predictive models. Typically, a choice must be made in favor of complex black box models such as recurrent neural networks (RNN) for accuracy versus less accurate but…

Machine Learning · Computer Science 2017-02-28 Edward Choi , Mohammad Taha Bahadori , Joshua A. Kulas , Andy Schuetz , Walter F. Stewart , Jimeng Sun

Due to the rapid growth of information available about individual patients, most physicians suffer from information overload when they review patient information in health information technology systems. In this manuscript, we present a…

Information Retrieval · Computer Science 2020-08-13 Ziwei Fan , Evan Burgun , Zhiyun Ren , Titus Schleyer , Xia Ning

We propose the molecular omics network (MOOMIN) a multimodal graph neural network used by AstraZeneca oncologists to predict the synergy of drug combinations for cancer treatment. Our model learns drug representations at multiple scales…

Machine Learning · Computer Science 2022-08-09 Benedek Rozemberczki , Anna Gogleva , Sebastian Nilsson , Gavin Edwards , Andriy Nikolov , Eliseo Papa

Traditional drug discovery processes are both time-consuming and require extensive professional expertise. With the accumulation of drug-target interaction (DTI) data from experimental studies, leveraging modern machine-learning techniques…

Quantitative Methods · Quantitative Biology 2024-12-12 Shuqi Li , Shufang Xie , Hongda Sun , Yuhan Chen , Tao Qin , Tianjun Ke , Rui Yan

Electronic Health Records (EHRs) provide rich longitudinal clinical evidence that is central to medical decision-making, motivating the use of retrieval-augmented generation (RAG) to ground large language model (LLM) predictions. However,…

Artificial Intelligence · Computer Science 2026-01-30 Lang Cao , Qingyu Chen , Yue Guo

Recently, substantial research has been conducted on sequential recommendation, with the objective of forecasting the subsequent item by leveraging a user's historical sequence of interacted items. Prior studies employ both capsule networks…

Information Retrieval · Computer Science 2025-05-01 Zhikai Wang , Yanyan Shen

Sum-product networks (SPNs) have recently emerged as a novel deep learning architecture enabling highly efficient probabilistic inference. Since their introduction, SPNs have been applied to a wide range of data modalities and extended to…

Machine Learning · Computer Science 2022-11-15 Adam Dejl , Harsh Deep , Jonathan Fei , Ardavan Saeedi , Li-wei H. Lehman

The inherent complexity of structured longitudinal Electronic Health Records (EHR) data poses a significant challenge when integrated with Large Language Models (LLMs), which are traditionally tailored for natural language processing.…

Computation and Language · Computer Science 2024-02-13 Yinghao Zhu , Zixiang Wang , Junyi Gao , Yuning Tong , Jingkun An , Weibin Liao , Ewen M. Harrison , Liantao Ma , Chengwei Pan

Machine learning (ML) has recently shown promising results in medical predictions using electronic health records (EHRs). However, since ML models typically have a limited capability in terms of input sizes, selecting specific medical…

Machine Learning · Computer Science 2024-07-23 Junu Kim , Chaeeun Shim , Bosco Seong Kyu Yang , Chami Im , Sung Yoon Lim , Han-Gil Jeong , Edward Choi

In recommendation systems, users frequently engage in multiple types of behaviors, such as clicking, adding to a cart, and purchasing. However, with diversified behavior data, user behavior sequences will become very long in the short term,…

Information Retrieval · Computer Science 2024-03-27 Yongqiang Han , Hao Wang , Kefan Wang , Likang Wu , Zhi Li , Wei Guo , Yong Liu , Defu Lian , Enhong Chen

Electronic Health Records (EHRs) enable deep learning for clinical predictions, but the optimal method for representing patient data remains unclear due to inconsistent evaluation practices. We present the first systematic benchmark to…

Machine Learning · Computer Science 2025-10-13 Tianyi Chen , Mingcheng Zhu , Zhiyao Luo , Tingting Zhu

The breadth, scale, and temporal granularity of modern electronic health records (EHR) systems offers great potential for estimating personalized and contextual patient health trajectories using sequential deep learning. However, learning…

The changing preferences of users towards items trigger the emergence of session-based recommender systems (SBRSs), which aim to model the dynamic preferences of users for next-item recommendations. However, most of the existing studies on…

Information Retrieval · Computer Science 2021-07-21 Wenzhuo Song , Shoujin Wang , Yan Wang , Shengsheng Wang

Electronic Health Record (EHR) tables pose unique challenges among which is the presence of hidden contextual dependencies between medical features with a high level of data dimensionality and sparsity. This study presents the first…

Computation and Language · Computer Science 2025-01-17 Jesus Lovon , Martin Mouysset , Jo Oleiwan , Jose G. Moreno , Christine Damase-Michel , Lynda Tamine

Healthcare data are inherently multimodal, including electronic health records (EHR), medical images, and multi-omics data. Combining these multimodal data sources contributes to a better understanding of human health and provides optimal…

Machine Learning · Computer Science 2022-10-28 Farida Mohsen , Hazrat Ali , Nady El Hajj , Zubair Shah

Predicting health risks from electronic health records (EHR) is a topic of recent interest. Deep learning models have achieved success by modeling temporal and feature interaction. However, these methods learn insufficient representations…

Machine Learning · Computer Science 2023-12-19 Zhihao Yu , Chaohe Zhang , Yasha Wang , Wen Tang , Jiangtao Wang , Liantao Ma

Electronic Health Records (EHRs) hold immense potential for advancing healthcare, offering rich, longitudinal data that combines structured information with valuable insights from unstructured clinical notes. However, the unstructured…

Computation and Language · Computer Science 2025-01-31 Huaiyuan Ying , Hongyi Yuan , Jinsen Lu , Zitian Qu , Yang Zhao , Zhengyun Zhao , Isaac Kohane , Tianxi Cai , Sheng Yu