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The innovation of next-generation sequencing (NGS) techniques has significantly reduced the price of genome sequencing, lowering barriers to future medical research; it is now feasible to apply genome sequencing to studies where it would…

Genomics · Quantitative Biology 2024-06-06 Arshmeet Kaur , Morteza Sarmadi

How to achieve better end-to-end speech translation (ST) by leveraging (text) machine translation (MT) data? Among various existing techniques, multi-task learning is one of the effective ways to share knowledge between ST and MT in which…

Computation and Language · Computer Science 2023-05-16 Qingkai Fang , Yang Feng

LLM-based automated program repair (APR) techniques have shown promising results in reducing debugging costs. However, prior results can be affected by data leakage: large language models (LLMs) may memorize bug fixes when evaluation…

Software Engineering · Computer Science 2026-04-24 Milan De Koning , Ali Asgari , Pouria Derakhshanfar , Annibale Panichella

Large Language Models (LLMs) are increasingly deployed in medical settings, yet their sensitivity to prompt formatting remains poorly characterized. We evaluate MedGemma (4B and 27B parameters) on MedMCQA (4,183 questions) and PubMedQA…

Computation and Language · Computer Science 2026-03-30 Binesh Sadanandan , Vahid Behzadan

Automated static analysis tools (ASATs) have become a major part of the software development workflow. Acting on the generated warnings, i.e., changing the code indicated in the warning, should be part of, at latest, the code review phase.…

Software Engineering · Computer Science 2021-09-09 Alexander Trautsch , Steffen Herbold , Jens Grabowski

Pretrained Foundation Models (PFMs) are regarded as the foundation for various downstream tasks with different data modalities. A PFM (e.g., BERT, ChatGPT, and GPT-4) is trained on large-scale data which provides a reasonable parameter…

Code-mixed data is an important challenge of natural language processing because its characteristics completely vary from the traditional structures of standard languages. In this paper, we propose a novel approach called Sentiment Analysis…

Computation and Language · Computer Science 2024-03-08 Nurendra Choudhary , Rajat Singh , Ishita Bindlish , Manish Shrivastava

We introduce Machine Learning as a Tool (MLAT), a design pattern in which pre-trained statistical machine learning models are exposed as callable tools within large language model (LLM) agent workflows. This allows an orchestrating agent to…

Machine Learning · Computer Science 2026-02-17 Edwin Chen , Zulekha Bibi

Pre-trained sequence-to-sequence models have significantly improved Neural Machine Translation (NMT). Different from prior works where pre-trained models usually adopt an unidirectional decoder, this paper demonstrates that pre-training a…

Computation and Language · Computer Science 2022-06-03 Pengfei Li , Liangyou Li , Meng Zhang , Minghao Wu , Qun Liu

Recent advances have shown that statistical tests for the rank of cross-covariance matrices play an important role in causal discovery. These rank tests include partial correlation tests as special cases and provide further graphical…

Machine Learning · Computer Science 2025-06-13 Xinshuai Dong , Ignavier Ng , Boyang Sun , Haoyue Dai , Guang-Yuan Hao , Shunxing Fan , Peter Spirtes , Yumou Qiu , Kun Zhang

Alignment, endowing a pre-trained Large language model (LLM) with the ability to follow instructions, is crucial for its real-world applications. Conventional supervised fine-tuning (SFT) methods formalize it as causal language modeling…

Computation and Language · Computer Science 2024-12-18 Yuchen Fan , Yuzhong Hong , Qiushi Wang , Junwei Bao , Hongfei Jiang , Yang Song

Test-time adaptation (TTA) is the problem of updating a pre-trained source model at inference time given test input(s) from a different target domain. Most existing TTA approaches assume the setting in which the target domain is stationary,…

Machine Learning · Computer Science 2023-04-05 Dhanajit Brahma , Piyush Rai

Genetic Programming yields interpretable programs, but small syntactic mutations can induce large, unpredictable behavioral shifts, degrading locality and sample efficiency. We frame this as an operator-design problem: learn a continuous…

Machine Learning · Computer Science 2026-02-10 Matthew Siper , Muhammad Umair Nasir , Ahmed Khalifa , Lisa Soros , Jay Azhang , Julian Togelius

Large Language Models (LLMs) often fail to generate correct code on the first attempt, which requires using generated unit tests as verifiers to validate the solutions. Despite the success of recent verification methods, they remain…

Artificial Intelligence · Computer Science 2026-03-03 Sicheng Zhu , Jiajun Wang , Jiawei Ai , Xin Li

Preference learning provides a promising solution to address the limitations of supervised fine-tuning (SFT) for code language models, where the model is not explicitly trained to differentiate between correct and incorrect code. Recent…

Computation and Language · Computer Science 2024-10-15 Dylan Zhang , Shizhe Diao , Xueyan Zou , Hao Peng

Parameter-Efficient Fine-Tuning (PEFT) is widely used for adapting Large Language Models (LLMs) for various tasks. Recently, there has been an increasing demand for fine-tuning a single LLM for multiple tasks because it requires overall…

Computation and Language · Computer Science 2026-05-15 Anjir Ahmed Chowdhury , Syed Zawad , Xiaolong Ma , Xu Dong , Feng Yan

Directed evolution plays an indispensable role in protein engineering that revises existing protein sequences to attain new or enhanced functions. Accurately predicting the effects of protein variants necessitates an in-depth understanding…

Quantitative Methods · Quantitative Biology 2023-06-09 Yang Tan , Bingxin Zhou , Yuanhong Jiang , Yu Guang Wang , Liang Hong

Pre-training a language model and then fine-tuning it for downstream tasks has demonstrated state-of-the-art results for various NLP tasks. Pre-training is usually independent of the downstream task, and previous works have shown that this…

Computation and Language · Computer Science 2022-11-28 Tanish Lad , Himanshu Maheshwari , Shreyas Kottukkal , Radhika Mamidi

Structured sparsity has emerged as a popular model pruning technique, widely adopted in various architectures, including CNNs, Transformer models, and especially large language models (LLMs) in recent years. A promising direction to further…

Machine Learning · Computer Science 2026-02-02 Zekai Li , Ji Liu , Guanchen Li , Yixing Xu , Ziqiong Liu , Xuanwu Yin , Dong Li , Emad Barsoum

Semantic parsing is a key NLP task that maps natural language to structured meaning representations. As in many other NLP tasks, SOTA performance in semantic parsing is now attained by fine-tuning a large pretrained language model (PLM).…

Computation and Language · Computer Science 2022-03-08 Weiqi Sun , Haidar Khan , Nicolas Guenon des Mesnards , Melanie Rubino , Konstantine Arkoudas