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Eukaryotic cell motility is crucial during development, wound healing, the immune response, and cancer metastasis. Some eukaryotic cells can swim, but cells more commonly adhere to and crawl along the extracellular matrix. We study the…

Cell Behavior · Quantitative Biology 2019-09-02 Melissa H. Mai , Brian A. Camley

By taking into account the hydrodynamic interactions in a one dimensional array of model cilia attached to a no-slip cylinderical surface, we investigate their synchronized motion. We show, how does the emergence of metachronal waves depend…

Biological Physics · Physics 2017-05-31 Aref Ghorbani , Ali Najafi

Bacterial colonies are a well-known example of living active matter, exhibiting collective behaviors such as nematic alignment and collective motion that play an important role in the spread of microbial infections. While the underlying…

The emerging field of self-driven active particles in fluid environments has recently created significant interest in the biophysics and bioengineering communities owing to their promising future biomedical and technological applications.…

Navigation of microorganisms is controlled by internal processes ultimately sensitive to mechanical or chemical signaling encountered along the path. In many natural environments, such as porous soils or physiological ducts, motile species…

The propulsion of many eukaryotic cells is generated by flagella, flexible slender filaments that are actively oscillating in space and time. The dynamics of these biological appendages have inspired the design of many types of artificial…

Soft Condensed Matter · Physics 2025-04-15 Mariia Dvoriashyna , Eric Lauga

Dynamic organization of the cytoskeletal filaments and rod-like proteins in the cell membrane and other biological interfaces occurs in many cellular processes. Previous modeling studies have considered the dynamics of a single rod on fluid…

Fluid Dynamics · Physics 2022-06-17 Wenzheng Shi , Moslem Moradi , Ehssan Nazockdast

Motile cilia are a striking example of functional cellular organelle, conserved across all the eukaryotic species. Motile cilia allow swimming of cells and small organisms and transport of liquids across epithelial tissues. Whilst the…

Tissues and Organs · Quantitative Biology 2020-01-13 Pietro Cicuta

The motility of microorganisms is influenced greatly by their hydrodynamic interactions with the fluidic environment they inhabit. We show by direct experimental observation of the bi-flagellated alga Chlamydomonas reinhardtii that fluid…

Biological Physics · Physics 2015-11-03 Boyang Qin , Arvind Gopinath , Jing Yang , Jerry P Gollub , Paulo E Arratia

The ability of cells to sense and respond to the mechanical properties of their environments is fundamental to a range of cellular behaviours, with substrate stiffness increasingly being found to be a key signalling factor. Although active…

Cell Behavior · Quantitative Biology 2019-09-04 Carina M. Dunlop

We investigate the synchronization properties of the two-dimensional periodic flow over a circular cylinder using the principles of phase-reduction theory. The influence of harmonic external forcings on the wake dynamics, and the possible…

Fluid Dynamics · Physics 2020-10-28 Mohammad Amin Khodkar , Kunihiko Taira

We study synchronization dynamics in networks of coupled oscillators with bimodal distribution of natural frequencies. This setup can be interpreted as a simple model of frequency synchronization dynamics among generators and loads working…

Physics and Society · Physics 2012-07-03 Sergi Lozano , Lubos Buzna , Albert Díaz-Guilera

Cytoplasmic streaming, the persistent flow of fluid inside a cell, induces intracellular transport, which plays a key role in fundamental biological processes. In meiosis II mouse oocytes (developing egg cells) awaiting fertilisation, the…

Biological Physics · Physics 2024-10-18 Weida Liao , Eric Lauga

The locomotion of microorganisms and spermatozoa in complex viscoelastic fluids is of critical importance in many biological processes such as fertilization, infection, and biofilm formation. Depending on their propulsion mechanisms,…

Soft Condensed Matter · Physics 2021-09-14 Gaojin Li , Eric Lauga , Arezoo M. Ardekani

Mechanical oscillations are important for many cellular processes, e.g. the beating of cilia and flagella or the sensation of sound by hair cells. These dynamic states originate from spontaneous oscillations of molecular motors. A…

Biological Physics · Physics 2009-01-29 Stefan Gunther , Karsten Kruse

There is evidence that ice age cycles are paced by astronomical forcing, suggesting some kind of synchronisation phenomenon. Here, we identify the type of such synchronisation and explore systematically its uniqueness and robustness using a…

Dynamical Systems · Mathematics 2013-11-15 B. De Saedeleer , M. Crucifix , S. Wieczorek

Modeling the dynamics of colloidal rods remains a central challenge in soft-matter physics due to the anisotropic and long-ranged nature of their interactions. Hydrodynamic interactions in rods suspensions are often assumed to be screened…

Soft Condensed Matter · Physics 2026-05-19 Lucas H. P. Cunha , Paul F. Salipante , Peter D. Olmsted , Steven D. Hudson

Synchronization is central to many complex systems in engineering physics (e.g., the power-grid, Josephson junction circuits, and electro-chemical oscillators) and biology (e.g., neuronal, circadian, and cardiac rhythms). Despite these…

Adaptation and Self-Organizing Systems · Physics 2017-01-13 Dane Taylor , Per Sebastian Skardal , Jie Sun

Coherent angular rotation of epithelial cells is thought to contribute to many vital physiological processes including tissue morphogenesis and glandular formation. However, factors regulating this motion, and the implications of this…

Cell Behavior · Quantitative Biology 2016-05-10 S. S. Soumya , Animesh Gupta , Andrea Cugno , Luca Deseri , Kaushik Dayal , Dibyendu Das , Shamik Sen , Mandar M. Inamdar

Periodically forced, oscillatory fluid flows have been the focus of intense research for decades due to their richness as a nonlinear dynamical system and their relevance to applications in transportation, aeronautics, and energy…

Fluid Dynamics · Physics 2020-02-03 Benjamin Herrmann , Philipp Oswald , Richard Semaan , Steven L. Brunton