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Lattice protein folding models are a cornerstone of computational biophysics. Although these models are a coarse grained representation, they provide useful insight into the energy landscape of natural proteins. Finding low-energy…

Quantum annealing is a type of analog computation that aims to use quantum mechanical fluctuations in search of optimal solutions of QUBO (quadratic unconstrained binary optimization) or, equivalently, Ising problems. Since NP-hard problems…

Quantum Physics · Physics 2023-04-14 Elijah Pelofske , Georg Hahn , Hristo N. Djidjev

The quest for real-time dynamic optimization solutions in the process industry represents a formidable computational challenge, particularly within the realm of applications like model-predictive control, where rapid and reliable…

Optimization and Control · Mathematics 2024-04-29 Dennis Michael Nenno , Adrian Caspari

Quantum annealing is a novel type of analog computation that aims to use quantum mechanical fluctuations to search for optimal solutions of Ising problems. Quantum annealing in the Transverse Ising model, implemented on D-Wave QPUs, are…

Quantum Physics · Physics 2025-03-14 Elijah Pelofske

Mixed-integer linear programming problems are extensively used in industry for a wide range of optimization tasks. However, as they get larger, they present computational challenges for classical solvers within practical time limits.…

Quantum Physics · Physics 2026-01-21 Sergio López-Baños , Elisabeth Lobe , Ontje Lünsdorf , Oriol Raventós

In this work, we explore graph partitioning (GP) using quantum annealing on the D-Wave 2X machine. Motivated by a recently proposed graph-based electronic structure theory applied to quantum molecular dynamics (QMD) simulations, graph…

Quantum Physics · Physics 2017-05-10 Hayato Ushijima-Mwesigwa , Christian F. A. Negre , Susan M. Mniszewski

Quantum computers use quantum resources to carry out computational tasks and may outperform classical computers in solving certain computational problems. Special-purpose quantum computers such as quantum annealers employ quantum adiabatic…

Other Statistics · Statistics 2021-01-19 Xinyu Song , Yazhen Wang , Shang Wu , Donggyu Kim

Quantum computing, along with quantum metrology and quantum communication, are disruptive technologies that promise, in the near future, to impact different sectors of academic research and industry. Among the computational challenges with…

Characterizing thermally activated transitions in high-dimensional rugged energy surfaces is a very challenging task for classical computers. Here, we develop a quantum annealing scheme to solve this problem. First, the task of finding the…

Quantum Physics · Physics 2021-01-18 Philipp Hauke , Giovanni Mattiotti , Pietro Faccioli

Quantum annealers, such as the device built by D-Wave Systems, Inc., offer a way to compute solutions of NP-hard problems that can be expressed in Ising or QUBO (quadratic unconstrained binary optimization) form. Although such solutions are…

Quantum Physics · Physics 2022-10-27 Aaron Barbosa , Elijah Pelofske , Georg Hahn , Hristo N. Djidjev

Quantum chemistry is regarded to be one of the first disciplines that will be revolutionized by quantum computing. Although universal quantum computers of practical scale may be years away, various approaches are currently being pursued to…

Quantum Physics · Physics 2021-01-29 Alexander Teplukhin , Brian K. Kendrick , Sergei Tretiak , Pavel A. Dub

The development of quantum-classical hybrid (QCH) algorithms is critical to achieve state-of-the-art computational models. A QCH variational autoencoder (QVAE) was introduced in Ref. [1] by some of the authors of this paper. QVAE consists…

We propose an experimental protocol for using cold atoms to create and probe quantum dimer models, thereby exploring the Pauling-Anderson vision of a macroscopic collection of resonating bonds. This process can allow the study of exotic…

Quantum Gases · Physics 2019-04-25 Bhuvanesh Sundar , Todd C. Rutkowski , Erich J. Mueller , Michael J. Lawler

In this paper, we review some features of quantum annealing and related topics from viewpoints of statistical physics, condensed matter physics, and computational physics. We can obtain a better solution of optimization problems in many…

Disordered Systems and Neural Networks · Physics 2017-08-23 Shu Tanaka , Ryo Tamura

Academic and industrial sectors have been engaged in a fierce competition to develop quantum technologies, fueled by the explosive advancements in quantum hardware. While universal quantum computers have been shown to support up to hundreds…

Quantum Physics · Physics 2024-07-04 Amedeo Bertuzzi , Davide Ferrari , Antonio Manzalini , Michele Amoretti

We leverage the idea of a statistical ensemble to improve the quality of quantum annealing based binary compressive sensing. Since executing quantum machine instructions on a quantum annealer can result in an excited state, rather than the…

Quantum Physics · Physics 2020-06-09 Ramin Ayanzadeh , Milton Halem , Tim Finin

Quantum annealing is a computational paradigm in which optimisation problems are mapped onto the energy landscape of an interacting quantum system and explored through its dynamical evolution. By continuously transforming a simple initial…

Quantum Physics · Physics 2026-05-11 Steven Abel , Andrei Constantin , Luca A. Nutricati

Boltzmann machine is a powerful machine learning model with many real-world applications, for example by constructing deep belief networks. Statistical inference on a Boltzmann machine can be carried out by sampling from its posterior…

Quantum Physics · Physics 2023-11-23 Mārtiņš Kālis , Andris Locāns , Rolands Šikovs , Hassan Naseri , Andris Ambainis

In our previous studies [1, 2], we confirmed that a quantum annealer can be used for importance sampling of gauge theories. In this paper, we extend the previous results to larger 2-dimensional and 4-dimensional lattices to generate…

High Energy Physics - Lattice · Physics 2025-04-03 Jangho Kim , Thomas Luu , Wolfgang Unger