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Identification and quantification of nuclei in colorectal cancer haematoxylin \& eosin (H\&E) stained histology images is crucial to prognosis and patient management. In computational pathology these tasks are referred to as nuclear…

Quantitative Methods · Quantitative Biology 2022-03-08 Muhammad Dawood , Raja Muhammad Saad Bashir , Srijay Deshpande , Manahil Raza , Adam Shephard

Motivated by applications in community detection and dense subgraph discovery, we consider new clustering objectives in hypergraphs and bipartite graphs. These objectives are parameterized by one or more resolution parameters in order to…

Data Structures and Algorithms · Computer Science 2020-06-22 Nate Veldt , Anthony Wirth , David F. Gleich

Many geometric estimation problems take the form of synchronization over the special Euclidean group: estimate the values of a set of poses given noisy measurements of a subset of their pairwise relative transforms. This problem is…

Robotics · Computer Science 2017-02-13 David M. Rosen , Luca Carlone , Afonso S. Bandeira , John J. Leonard

In this paper, a new information theoretic framework for graph matching is introduced. Using this framework, the graph isomorphism and seeded graph matching problems are studied. The maximum degree algorithm for graph isomorphism is…

Information Theory · Computer Science 2017-11-29 F. Shirani , S. Garg , E. Erkip

Automation-assisted cervical screening via Pap smear or liquid-based cytology (LBC) is a highly effective cell imaging based cancer detection tool, where cells are partitioned into "abnormal" and "normal" categories. However, the success of…

Computer Vision and Pattern Recognition · Computer Science 2018-01-29 Ling Zhang , Le Lu , Isabella Nogues , Ronald M. Summers , Shaoxiong Liu , Jianhua Yao

This paper provides a new similarity detection algorithm. Given an input set of multi-dimensional data points, where each data point is assumed to be multi-dimensional, and an additional reference data point for similarity finding, the…

Artificial Intelligence · Computer Science 2017-07-12 Yariv Aizenbud , Amir Averbuch , Gil Shabat , Guy Ziv

We present an exact algorithm for computing all common subgraphs with the maximum number of vertices across multiple graphs. Our approach is further extended to handle the connected Maximum Common Subgraph (MCS), identifying the largest…

Data Structures and Algorithms · Computer Science 2025-04-03 Johannes B. S. Petersen , Akbar Davoodi , Thomas Gärtner , Marc Hellmuth , Daniel Merkle

We propose a simple, powerful, and flexible machine learning framework for (i) reducing the search space of computationally difficult enumeration variants of subset problems and (ii) augmenting existing state-of-the-art solvers with…

Machine Learning · Computer Science 2019-02-25 Juho Lauri , Sourav Dutta

Automatic cell detection in histology images is a challenging task due to varying size, shape and features of cells and stain variations across a large cohort. Conventional deep learning methods regress the probability of each pixel…

Computer Vision and Pattern Recognition · Computer Science 2018-06-20 Shan E Ahmed Raza , Khalid AbdulJabbar , Mariam Jamal-Hanjani , Selvaraju Veeriah , John Le Quesne , Charles Swanton , Yinyin Yuan

This work uses visual knowledge discovery in parallel coordinates to advance methods of interpretable machine learning. The graphic data representation in parallel coordinates made the concepts of hypercubes and hyperblocks (HBs) simple to…

Machine Learning · Computer Science 2023-11-28 Dustin Hayes , Boris Kovalerchuk

We propose a theoretical framework of multi-way similarity to model real-valued data into hypergraphs for clustering via spectral embedding. For graph cut based spectral clustering, it is common to model real-valued data into graph by…

Machine Learning · Computer Science 2022-08-17 Shota Saito

Learning faithful graph representations as sets of vertex embeddings has become a fundamental intermediary step in a wide range of machine learning applications. The quality of the embeddings is usually determined by how well the geometry…

Machine Learning · Computer Science 2021-05-13 Federico López , Beatrice Pozzetti , Steve Trettel , Anna Wienhard

This paper aims for set-to-hypergraph prediction, where the goal is to infer the set of relations for a given set of entities. This is a common abstraction for applications in particle physics, biological systems, and combinatorial…

Machine Learning · Computer Science 2023-01-18 David W. Zhang , Gertjan J. Burghouts , Cees G. M. Snoek

One of the biggest challenges in biology is to understand how activity at the cellular level of neurons, as a result of their mutual interactions, leads to the observed behavior of an organism responding to a variety of environmental…

Neurons and Cognition · Quantitative Biology 2010-03-09 Raj Kumar Pan , Nivedita Chatterjee , Sitabhra Sinha

Caenorhabditis elegans (C. elegans) illustrated remarkable behavioral plasticities including complex non-associative and associative learning representations. Understanding the principles of such mechanisms presumably leads to constructive…

Neurons and Cognition · Quantitative Biology 2017-03-28 Ramin M. Hasani , Magdalena Fuchs , Victoria Beneder , Radu Grosu

Nuclear segmentation is an important step for profiling aberrant regions of histology sections. However, segmentation is a complex problem as a result of variations in nuclear geometry (e.g., size, shape), nuclear type (e.g., epithelial,…

Computer Vision and Pattern Recognition · Computer Science 2018-02-16 Mina Khoshdeli , Bahram Parvin

The presented algorithms for segmentation and tracking follow a 3-step approach where we detect, track and finally segment nuclei. In the preprocessing phase, we detect centroids of the cell nuclei using a convolutional neural network (CNN)…

Computer Vision and Pattern Recognition · Computer Science 2019-04-16 Dennis Eschweiler , Johannes Stegmaier

Many important geometric estimation problems take the form of synchronization over the special Euclidean group: estimate the values of a set of poses given a set of relative measurements between them. This problem is typically formulated as…

Robotics · Computer Science 2017-02-07 David M. Rosen , Luca Carlone , Afonso S. Bandeira , John J. Leonard

Problems in scientific computing, such as distributing large sparse matrix operations, have analogous formulations as hypergraph partitioning problems. A hypergraph is a generalization of a traditional graph wherein "hyperedges" may connect…

Data Structures and Algorithms · Computer Science 2022-06-16 Justin Sybrandt , Ruslan Shaydulin , Ilya Safro

The nematode Caenorhabditis elegans is a well-known model organism used to investigate fundamental questions in biology. Motility assays of this small roundworm are designed to study the relationships between genes and behavior. Commonly,…

Computer Vision and Pattern Recognition · Computer Science 2015-05-19 Raphael Sznitman , Manaswi Gupta , Gregory D. Hager , Paulo E. Arratia , Josue Sznitman
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