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We develop a framework for post model selection inference, via marginal screening, in linear regression. At the core of this framework is a result that characterizes the exact distribution of linear functions of the response $y$,…

Methodology · Statistics 2014-03-03 Jason D Lee , Jonathan E Taylor

Subset selection for multiple linear regression aims to construct a regression model that minimizes errors by selecting a small number of explanatory variables. Once a model is built, various statistical tests and diagnostics are conducted…

Machine Learning · Statistics 2020-09-04 Seokhyun Chung , Young Woong Park , Taesu Cheong

Nonlinear Mixed effects models are hidden variables models that are widely used in many fields such as pharmacometrics. In such models, the distribution characteristics of hidden variables can be specified by including several parameters…

Methodology · Statistics 2021-10-19 Edouard Ollier

Forward regression is a crucial methodology for automatically identifying important predictors from a large pool of potential covariates. In contexts with moderate predictor correlation, forward selection techniques can achieve screening…

Methodology · Statistics 2024-08-23 Xuejun Jiang , Yue Ma , Haofeng Wang

This paper treats the problem of screening for variables with high correlations in high dimensional data in which there can be many fewer samples than variables. We focus on threshold-based correlation screening methods for three related…

Machine Learning · Statistics 2015-03-18 Alfred O. Hero , Bala Rajaratnam

Background: The availability of high throughput methods for measurement of mRNA concentrations makes the reliability of conclusions drawn from the data and global quality control of samples and hybridization important issues. We address…

Quantitative Methods · Quantitative Biology 2007-05-23 S. Bilke , T. Breslin , M. Sigvardsson

Randomization, as a key technique in clinical trials, can eliminate sources of bias and produce comparable treatment groups. In randomized experiments, the treatment effect is a parameter of general interest. Researchers have explored the…

Methodology · Statistics 2023-12-05 Fuyi Tu , Wei Ma , Hanzhong Liu

We consider the problem of estimation of a covariance matrix for Gaussian data in a high dimensional setting. Existing approaches include maximum likelihood estimation under a pre-specified sparsity pattern, l_1-penalized loglikelihood…

Methodology · Statistics 2024-10-04 Luca Cibinel , Alberto Roverato , Veronica Vinciotti

Covariance regression offers an effective way to model the large covariance matrix with the auxiliary similarity matrices. In this work, we propose a sparse covariance regression (SCR) approach to handle the potentially high-dimensional…

Methodology · Statistics 2024-10-17 Yuan Gao , Zhiyuan Zhang , Zhanrui Cai , Xuening Zhu , Tao Zou , Hansheng Wang

Tens of thousands of simultaneous hypothesis tests are routinely performed in genomic studies to identify differentially expressed genes. However, due to unmeasured confounders, many standard statistical approaches may be substantially…

Methodology · Statistics 2025-03-18 Jin-Hong Du , Larry Wasserman , Kathryn Roeder

Variable selection in high dimensional space has challenged many contemporary statistical problems from many frontiers of scientific disciplines. Recent technology advance has made it possible to collect a huge amount of covariate…

Machine Learning · Statistics 2010-05-20 Jianqing Fan , Yang Feng , Yichao Wu

We consider a method to jointly estimate sparse precision matrices and their underlying graph structures using dependent high-dimensional datasets. We present a penalized maximum likelihood estimator which encourages both sparsity and…

Applications · Statistics 2016-08-22 Adria Caballe , Natalia Bochkina , Claus Mayer

In large-scale biomedical research, it's common to gather ultra-high dimensional data that includes right-censored survival times. Feature screening has emerged as a crucial statistical technique for handling such data. In this paper, we…

Methodology · Statistics 2026-03-31 Shuya Chen , Heng Peng , Min Zhou

We propose an iterative variable selection method for the accelerated failure time model using high-dimensional survival data. Our method pioneers the use of the recently proposed structured screen-and-select framework for survival…

Methodology · Statistics 2025-03-04 Nilotpal Sanyal

In recent years, deep learning has been at the center of analytics due to its impressive empirical success in analyzing complex data objects. Despite this success, most of the existing tools behave like black-box machines, thus the…

Machine Learning · Statistics 2022-11-02 Arkaprabha Ganguli , David Todem , Tapabrata Maiti

As a computationally fast and working efficient tool, sure independence screening has received much attention in solving ultrahigh dimensional problems. This paper contributes two robust sure screening approaches that simultaneously take…

Methodology · Statistics 2021-07-27 Xiaochao Xia

The problem of detecting change points in the parameters of a linear regression model with errors and covariates exhibiting heteroscedasticity is considered. Asymptotic results for weighted functionals of the cumulative sum (CUSUM)…

Econometrics · Economics 2025-10-28 Lajos Horvath , Gregory Rice , Yuqian Zhao

In many problems involving generalized linear models, the covariates are subject to measurement error. When the number of covariates p exceeds the sample size n, regularized methods like the lasso or Dantzig selector are required. Several…

Methodology · Statistics 2018-01-23 Øystein Sørensen , Arnoldo Frigessi , Magne Thoresen

In recent years, a rich variety of regularization procedures have been proposed for high dimensional regression problems. However, tuning parameter choice and computational efficiency in ultra-high dimensional problems remain vexing issues.…

Computation · Statistics 2012-01-18 Hua Zhou , Artin Armagan , David B. Dunson

High-dimensional data are commonly seen in modern statistical applications, variable selection methods play indispensable roles in identifying the critical features for scientific discoveries. Traditional best subset selection methods are…

Methodology · Statistics 2022-12-29 Tianzhou Ma , Hongjie Ke , Zhao Ren
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