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Maternal exposure to environmental chemicals during pregnancy can alter birth and children's health outcomes. Research seeks to identify critical windows, time periods when the exposures can change future health outcomes, and estimate the…

Methodology · Statistics 2022-04-14 Daniel Mork , Ander Wilson

Distributed lag models are useful in environmental epidemiology as they allow the user to investigate critical windows of exposure, defined as the time period during which exposure to a pollutant adversely affects health outcomes. Recent…

Methodology · Statistics 2021-08-02 Joseph Antonelli , Ander Wilson , Brent Coull

Exposures to environmental chemicals during gestation can alter health status later in life. Most studies of maternal exposure to chemicals during pregnancy have focused on a single chemical exposure observed at high temporal resolution.…

Children's health studies support an association between maternal environmental exposures and children's birth outcomes. A common goal is to identify critical windows of susceptibility--periods during gestation with increased association…

Fine particulate matter (PM2.5) measured at a given location is a mix of pollution generated locally and pollution traveling long distances in the atmosphere. Therefore, the identification of spatial scales associated with health effects…

Methodology · Statistics 2016-09-19 Joseph Antonelli , Joel Schwartz , Itai Kloog , Brent Coull

Recent studies of associations between environmental exposures and health outcomes have shifted toward estimating the effect of simultaneous exposure to multiple chemicals. Summary index methods, such as the weighted quantile sum and…

Applications · Statistics 2025-02-21 Jacob Englert , Howard Chang

Air and water pollution are major threats to public health, highlighting the need for reliable environmental monitoring. Low-cost multisensor systems are promising but suffer from limited selectivity, because their responses are influenced…

Applications · Statistics 2025-07-08 Marine Dumon , Berengere Lebental , Guillaume Perrin

Humans are routinely exposed to mixtures of chemical and other environmental factors, making the quantification of health effects associated with environmental mixtures a critical goal for establishing environmental policy sufficiently…

Evaluating the causal health effects of multivariate, continuous exposures, such as air pollution mixtures, is a critical public health challenge. A primary obstacle is the frequent violation of the positivity assumption, which renders the…

Methodology · Statistics 2026-05-05 Zhuochao Huang , Kejin Dong , Tuo Lin , Joseph Antonelli

Maternal exposure to air pollution during pregnancy has a substantial public health impact. Epidemiological evidence supports an association between maternal exposure to air pollution and low birth weight. A popular method to estimate this…

Estimating the joint effect of a multivariate, continuous exposure is crucial, particularly in environmental health where interest lies in simultaneously evaluating the impact of multiple environmental pollutants on health. We develop novel…

Exposure assessment is fundamental to air pollution cohort studies. The objective is to predict air pollution exposures for study subjects at locations without data in order to optimize our ability to learn about health effects of air…

Applications · Statistics 2024-06-05 Si Cheng , Magali N. Blanco , Lianne Sheppard , Ali Shojaie , Adam Szpiro

Exposure to environmental pollutants during the gestational period can significantly impact infant health outcomes, such as birth weight and neurological development. Identifying critical windows of susceptibility, which are specific…

Applications · Statistics 2024-08-19 Yisen Jin , Aaron J. Molstad , Ander Wilson , Joseph Antonelli

Pollutant exposure during gestation is a known and adverse factor for birth and health outcomes. However, the links between prenatal air pollution exposures and educational outcomes are less clear, in particular the critical windows of…

Methodology · Statistics 2022-10-11 Yunan Gao , Daniel R. Kowal

Humans are exposed to complex mixtures of environmental pollutants rather than single chemicals, necessitating methods to quantify the health effects of such mixtures. Research on environmental mixtures provides insights into realistic…

Methodology · Statistics 2026-04-09 Aaron Sonabend , Jiangshan Zhang , Edgar Castro , Joel Schwartz , Brent A. Coull , Junwei Lu

This manuscript presents a novel Bayesian varying coefficient quantile regression (BVCQR) model designed to assess the longitudinal effects of chemical exposure mixtures on children's neurodevelopment. Recognizing the complexity and…

Applications · Statistics 2024-04-22 Wei Jia , Roman Jandarov

Epidemiological research supports an association between maternal exposure to air pollution during pregnancy and adverse children's health outcomes. Advances in exposure assessment and statistics allow for estimation of both critical…

Laboratory experiments have shown that cardiovascular diseases are positively correlated to the concentration of ambient air pollutants, such as SO2, NO2, PM10, etc. It has also been repeatedly reported in many countries that increased…

Applications · Statistics 2013-08-08 Menghui Li , Dasheng Luo , Chenghua Cao , Xiaochuan Pan , Qixin Wang

Studies of the relationships between environmental exposures and adverse health outcomes often rely on a two-stage statistical modeling approach, where exposure is modeled/predicted in the first stage and used as input to a separately fit…

Methodology · Statistics 2022-04-01 Saskia Comess , Howard H. Chang , Joshua L. Warren

The analysis of environmental mixtures is of growing importance in environmental epidemiology, and one of the key goals in such analyses is to identify exposures and their interactions that are associated with adverse health outcomes.…

Methodology · Statistics 2021-03-22 Srijata Samanta , Joseph Antonelli
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