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This paper proposes a new approach for solving ill-posed nonlinear inverse problems. For ease of explanation of the proposed approach, we use the example of lung electrical impedance tomography (EIT), which is known to be a nonlinear and…

Numerical Analysis · Mathematics 2019-08-01 Jin Keun Seo , Kang Cheol Kim , Ariungerel Jargal , Kyounghun Lee , Bastian Harrach

Electrical Impedance Tomography (EIT) is a powerful imaging technique with diverse applications, e.g., medical diagnosis, industrial monitoring, and environmental studies. The EIT inverse problem is about inferring the internal conductivity…

Machine Learning · Computer Science 2023-10-31 Derick Nganyu Tanyu , Jianfeng Ning , Andreas Hauptmann , Bangti Jin , Peter Maass

Biomedical photoacoustic tomography, which can provide high resolution 3D soft tissue images based on the optical absorption, has advanced to the stage at which translation from the laboratory to clinical settings is becoming possible. The…

Image and Video Processing · Electrical Eng. & Systems 2020-11-20 Andreas Hauptmann , Ben Cox

Photoacoustic tomography (PAT) is a medical imaging modality that can provide high-resolution tissue images based on the optical absorption. Classical reconstruction methods for quantifying the absorption coefficients rely on sufficient…

Image and Video Processing · Electrical Eng. & Systems 2026-04-24 Anssi Manninen , Janek Gröhl , Felix Lucka , Andreas Hauptmann

Tomographic image reconstruction is relevant for many medical imaging modalities including X-ray, ultrasound (US) computed tomography (CT) and photoacoustics, for which the access to full angular range tomographic projections might be not…

Image and Video Processing · Electrical Eng. & Systems 2019-06-14 Valery Vishnevskiy , Richard Rau , Orcun Goksel

In this paper, we present a novel reconstruction method for diffuse optical spectroscopic imaging with a commonly used tissue model of optical absorption and scattering. It is based on linearization and group sparsity, which allows…

Numerical Analysis · Mathematics 2019-03-06 Habib Ammari , Bangti Jin , Wenlong Zhang

This paper aims to solve numerically the two-dimensional inverse medium scattering problem with far-field data. This is a challenging task due to the severe ill-posedness and strong nonlinearity of the inverse problem. As already known, it…

Numerical Analysis · Mathematics 2025-09-25 Kai Li , Bo Zhang , Haiwen Zhang

This paper presents a neural network approach for solving two-dimensional optical tomography (OT) problems based on the radiative transfer equation. The mathematical problem of OT is to recover the optical properties of an object based on…

Computational Physics · Physics 2019-10-14 Yuwei Fan , Lexing Ying

This work has been submitted to the IEEE for possible publication. Copyright may be transferred without notice, after which this version may no longer be accessible. Computational imaging, especially non-line-of-sight (NLOS) imaging, the…

Computer Vision and Pattern Recognition · Computer Science 2026-04-01 Lianfang Wang , Kuilin Qin , Xueying Liu , Huibin Chang , Yong Wang , Yuping Duan

Limited-Angle Computed Tomography (LACT) is a non-destructive evaluation technique used in a variety of applications ranging from security to medicine. The limited angle coverage in LACT is often a dominant source of severe artifacts in the…

Image and Video Processing · Electrical Eng. & Systems 2022-11-23 Jiaming Liu , Rushil Anirudh , Jayaraman J. Thiagarajan , Stewart He , K. Aditya Mohan , Ulugbek S. Kamilov , Hyojin Kim

Diffusion models have achieved excellent success in solving inverse problems due to their ability to learn strong image priors, but existing approaches require a large training dataset of images that should come from the same distribution…

Computer Vision and Pattern Recognition · Computer Science 2024-10-16 Jason Hu , Bowen Song , Jeffrey A. Fessler , Liyue Shen

Electrical impedance tomography (EIT) is an imaging modality in which the conductivity distribution inside a target is reconstructed based on voltage measurements from the surface of the target. Reconstructing the conductivity distribution…

Mathematical Physics · Physics 2012-07-05 Antti Lipponen , Aku Seppänen , Jari Kaipio

Optical diffraction tomography relies on solving an inverse scattering problem governed by the wave equation. Classical reconstruction algorithms are based on linear approximations of the forward model (Born or Rytov), which limits their…

Computational Engineering, Finance, and Science · Computer Science 2017-09-01 Emmanuel Soubies , Thanh-An Pham , Michael Unser

Diffusion models have been demonstrated as powerful deep learning tools for image generation in CT reconstruction and restoration. Recently, diffusion posterior sampling, where a score-based diffusion prior is combined with a likelihood…

Medical Physics · Physics 2024-09-02 Shudong Li , Xiao Jiang , Matthew Tivnan , Grace J. Gang , Yuan Shen , J. Webster Stayman

This paper describes the mathematical structure of the ill-posed nonlinear inverse problem of low-dose dental cone-beam computed tomography (CBCT) and explains the advantages of a deep learning-based approach to the reconstruction of…

Image and Video Processing · Electrical Eng. & Systems 2023-03-06 Hyoung Suk Park , Chang Min Hyun , Jin Keun Seo

We propose a method to reconstruct the optical absorption of a highly-scattering medium probed by diffuse light. The method consists of learning the optical detection system and then using this result to reconstruct the absorption. Our…

Optics · Physics 2025-10-08 Zijian Wang , Andreas Hauptmann , Lu Lu , John C. Schotland

We develop a novel deep learning technique, termed Deep Orthogonal Decomposition (DOD), for dimensionality reduction and reduced order modeling of parameter dependent partial differential equations. The approach consists in the construction…

Numerical Analysis · Mathematics 2024-05-15 Nicola Rares Franco , Andrea Manzoni , Paolo Zunino , Jan S. Hesthaven

Computed Tomography (CT) is widely used in healthcare for detailed imaging. However, Low-dose CT, despite reducing radiation exposure, often results in images with compromised quality due to increased noise. Traditional methods, including…

Image and Video Processing · Electrical Eng. & Systems 2024-09-17 Herman Verinaz-Jadan , Su Yan

Applying standard algorithms to sparse data problems in photoacoustic tomography (PAT) yields low-quality images containing severe under-sampling artifacts. To some extent, these artifacts can be reduced by iterative image reconstruction…

Numerical Analysis · Mathematics 2024-12-20 Stephan Antholzer , Johannes Schwab , Robert Nuster , Markus Haltmeier

Diffusion models have emerged as powerful priors for solving inverse problems in computed tomography (CT). In certain applications, such as neutron CT, it can be expensive to collect large amounts of measurements even for a single scan,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Timofey Efimov , Singanallur Venkatakrishnan , Maliha Hossain , Haley Duba-Sullivan , Amirkoushyar Ziabari