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In this paper we focus on comparative diagnostic trials which are frequently employed to compare two markers with continuous or ordinal results. We derive explicit expressions for the optimal sampling ratio based on a common variance…

Applications · Statistics 2012-06-19 Ting Dong , Liansheng Larry Tang , William F. Rosenberger

Multiple diagnostic tests are frequently used to determine the presence of a disease condition in patients. In this paper, we use bivariate copulas to examine the properties of receiver operating characteristic (ROC) curves formed when two…

In analysis of binary outcomes, the receiver operator characteristic (ROC) curve is heavily used to show the performance of a model or algorithm. The ROC curve is informative about the performance over a series of thresholds and can be…

Computation · Statistics 2020-08-10 John Muschelli

Prior to clinical applications, it is critical that risk prediction models are evaluated in independent studies that did not contribute to model development. While prospective cohort studies provide a natural setting for model validation,…

Methodology · Statistics 2017-10-13 Parichoy Pal Choudhury , Anil K. Chaturvedi , Nilanjan Chatterjee

We present a novel analytical framework to characterize the distribution of the conditional receiver operating characteristic (ROC) in radar systems operating within a realization of a Poisson field of interferers and clutters. While…

Information Theory · Computer Science 2025-05-28 Gourab Ghatak

Functional markers become a more frequent tool in medical diagnosis. In this paper, we aim to define an index allowing to discriminate between populations when the observations are functional data belonging to a Hilbert space. We discuss…

Methodology · Statistics 2025-02-03 Ana M. Bianco , Graciela Boente , Juan Carlos Pardo-Fernández

Receiver operating characteristic (ROC) curves are widely used as a measure of accuracy of diagnostic tests and can be summarized using the area under the ROC curve (AUC). Often, it is useful to construct a confidence intervals for the AUC,…

Applications · Statistics 2018-04-18 Hunyong Cho , Gregory J. Matthews , Ofer Harel

Accurate diagnosis of disease is of great importance in clinical practice and medical research. The receiver operating characteristic (ROC) surface is a popular tool for evaluating the discriminatory ability of continuous diagnostic test…

Methodology · Statistics 2018-05-22 Vanda Inacio de Carvalho , Miguel de Carvalho , Adam Branscum

Receiver Operating Characteristic (ROC) curves are plots of true positive rate versus false positive rate which are useful for evaluating binary classification models, but difficult to use for learning since the Area Under the Curve (AUC)…

Machine Learning · Statistics 2021-07-06 Jonathan Hillman , Toby Dylan Hocking

Optimal performance is critical for decision-making tasks from medicine to autonomous driving, however common performance measures may be too general or too specific. For binary classifiers, diagnostic tests or prognosis at a timepoint,…

Objectives: This study provides an effective model selection method based on the empirical likelihood approach for constructing summary receiver operating characteristic (sROC) curves from meta-analyses of diagnostic studies. Methods: We…

Methodology · Statistics 2018-03-13 ShengLi Tzeng , Chun-Shu Chen , Yu-Fen Li , Jin-Hua Chen

We have carried out a pilot study on a standard collection of electrocardiograms from patients who suffer from congestive heart failure, and subjects without cardiac pathology, using receiver-operating-characteristic (ROC) analysis. The…

chao-dyn · Physics 2007-05-23 Stefan Thurner , Markus C. Feurstein , Malvin C. Teich

The proper use of model evaluation metrics is important for model evaluation and model selection in binary classification tasks. This study investigates how consistent different metrics are at evaluating models across data of different…

Machine Learning · Statistics 2024-12-17 Jing Li

In this review, we present an overview of the main aspects related to the statistical evaluation of medical tests for diagnosis and prognosis. Measures of diagnostic performance for binary tests, such as sensitivity, specificity, and…

Methodology · Statistics 2020-07-16 Vanda Inacio , Maria Xose Rodriguez-Alvarez , Pilar Gayoso-Diz

To detect differences between the mean curves of two samples in longitudinal study or functional data analysis, we usually need to partition the temporal or spatial domain into several pre-determined sub-areas. In this paper we apply the…

Methodology · Statistics 2015-05-01 Peirong Xu , Youngjo Lee , Jian Qing Shi

Verification bias is a well known problem when the predictive ability of a diagnostic test has to be evaluated. In this paper, we discuss how to assess the accuracy of continuous-scale diagnostic tests in the presence of verification bias,…

Methodology · Statistics 2016-04-19 Khanh To Duc , Monica Chiogna , Gianfranco Adimari

Receiver Operating Characteristic (ROC) curves are plots of true positive rate versus false positive rate which are used to evaluate binary classification algorithms. Because the Area Under the Curve (AUC) is a constant function of the…

Machine Learning · Computer Science 2023-02-23 Kyle R. Rust , Toby D. Hocking

Hypothesis testing procedures are developed to assess linear operator constraints in function-on-scalar regression when incomplete functional responses are observed. The approach enables statistical inferences about the shape and other…

Methodology · Statistics 2022-12-06 Yeonjoo Park , Kyunghee Han , Douglas G. Simpson

We propose a method for maximizing a partial area under a receiver operating characteristic (ROC) curve (pAUC) for binary classification tasks. In binary classification tasks, accuracy is the most commonly used as a measure of classifier…

Machine Learning · Statistics 2018-06-14 Naonori Ueda , Akinori Fujino

Area Under the Receiver Operating Characteristic Curve (AUC-ROC) is a popular evaluation metric for binary classifiers. In this paper, we discuss techniques to segment the AUC-ROC along human-interpretable dimensions. AUC-ROC is not an…

Machine Learning · Computer Science 2022-05-25 Arya Tafvizi , Besim Avci , Mukund Sundararajan