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Related papers: MEG: Generating Molecular Counterfactual Explanati…

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Counterfactual Explanation (CE) techniques have garnered attention as a means to provide insights to the users engaging with AI systems. While extensively researched in domains such as medical imaging and autonomous vehicles, Graph…

Machine Learning · Computer Science 2024-01-12 Mario Alfonso Prado-Romero , Bardh Prenkaj , Giovanni Stilo

Financial cybercrime prevention is an increasing issue with many organisations and governments. As deep learning models have progressed to identify illicit activity on various financial and social networks, the explainability behind the…

Machine Learning · Computer Science 2023-10-24 Jack Nicholls , Aditya Kuppa , Nhien-An Le-Khac

The task here is to predict the toxicological activity of chemical compounds based on the Tox21 dataset, a benchmark in computational toxicology. After a domain-specific overview of chemical toxicity, we discuss current computational…

Machine Learning · Computer Science 2025-10-28 Eduard Popescu , Adrian Groza , Andreea Cernat

Artificial intelligence (AI) systems utilizing deep neural networks (DNNs) and machine learning (ML) algorithms are widely used for solving important problems in bioinformatics, biomedical informatics, and precision medicine. However,…

Quantitative Methods · Quantitative Biology 2023-02-24 Md. Rezaul Karim , Tanhim Islam , Oya Beyan , Christoph Lange , Michael Cochez , Dietrich Rebholz-Schuhmann , Stefan Decker

An increasing ubiquity of machine learning (ML) motivates research on algorithms to explain ML models and their predictions -- so-called eXplainable Artificial Intelligence (XAI). Despite many survey papers and discussions, the goals and…

Machine Learning · Computer Science 2024-07-16 Moritz Renftle , Holger Trittenbach , Michael Poznic , Reinhard Heil

Designing new molecules with a set of predefined properties is a core problem in modern drug discovery and development. There is a growing need for de-novo design methods that would address this problem. We present MolecularRNN, the graph…

Machine Learning · Computer Science 2019-06-03 Mariya Popova , Mykhailo Shvets , Junier Oliva , Olexandr Isayev

Graph Neural Networks (GNNs) have become a building block in graph data processing, with wide applications in critical domains. The growing needs to deploy GNNs in high-stakes applications necessitate explainability for users in the…

Drug Discovery is a fundamental and ever-evolving field of research. The design of new candidate molecules requires large amounts of time and money, and computational methods are being increasingly employed to cut these costs. Machine…

Machine Learning · Statistics 2021-05-28 Pietro Bongini , Monica Bianchini , Franco Scarselli

Knowledge graphs (KGs) are powerful tools for modelling complex, multi-relational data and supporting hypothesis generation, particularly in applications like drug repurposing. However, for predictive methods to gain acceptance as credible…

Artificial Intelligence · Computer Science 2026-02-06 Susana Nunes , Samy Badreddine , Catia Pesquita

Meta-learning is a field that aims at discovering how different machine learning algorithms perform on a wide range of predictive tasks. Such knowledge speeds up the hyperparameter tuning or feature engineering. With the use of surrogate…

Machine Learning · Statistics 2021-07-13 Katarzyna Woźnica , Przemysław Biecek

Graph neural networks (GNNs) find applications in various domains such as computational biology, natural language processing, and computer security. Owing to their popularity, there is an increasing need to explain GNN predictions since…

Machine Learning · Computer Science 2022-11-14 Mert Kosan , Zexi Huang , Sourav Medya , Sayan Ranu , Ambuj Singh

As the field of healthcare increasingly adopts artificial intelligence, it becomes important to understand which types of explanations increase transparency and empower users to develop confidence and trust in the predictions made by…

Artificial Intelligence · Computer Science 2025-05-16 Felix Liedeker , Olivia Sanchez-Graillet , Moana Seidler , Christian Brandt , Jörg Wellmer , Philipp Cimiano

Explainable AI(XAI)is a domain focused on providing interpretability and explainability of a decision-making process. In the domain of law, in addition to system and data transparency, it also requires the (legal-) decision-model…

Human-Computer Interaction · Computer Science 2020-12-18 Lukasz Gorski , Shashishekar Ramakrishna , Jedrzej M. Nowosielski

How to produce expressive molecular representations is a fundamental challenge in AI-driven drug discovery. Graph neural network (GNN) has emerged as a powerful technique for modeling molecular data. However, previous supervised approaches…

Machine Learning · Computer Science 2020-12-22 Pengyong Li , Jun Wang , Yixuan Qiao , Hao Chen , Yihuan Yu , Xiaojun Yao , Peng Gao , Guotong Xie , Sen Song

There is a disconnect between explanatory artificial intelligence (XAI) methods and the types of explanations that are useful for and demanded by society (policy makers, government officials, etc.) Questions that experts in artificial…

Artificial Intelligence · Computer Science 2019-01-23 Leilani H. Gilpin , Cecilia Testart , Nathaniel Fruchter , Julius Adebayo

Sensor-based Human Activity Recognition (HAR) in smart home environments is crucial for several applications, especially in the healthcare domain. The majority of the existing approaches leverage deep learning models. While these approaches…

Artificial Intelligence · Computer Science 2026-01-06 Michele Fiori , Davide Mor , Gabriele Civitarese , Claudio Bettini

Research into 6G networks has been initiated to support a variety of critical artificial intelligence (AI) assisted applications such as autonomous driving. In such applications, AI-based decisions should be performed in a real-time manner.…

Artificial Intelligence · Computer Science 2023-12-07 Abdul Karim Gizzini , Yahia Medjahdi , Ali J. Ghandour , Laurent Clavier

Explainable AI (XAI) methods focus on explaining what a neural network has learned - in other words, identifying the features that are the most influential to the prediction. In this paper, we call them "distinguishing features". However,…

Computer Vision and Pattern Recognition · Computer Science 2021-04-19 Kaili Wang , Jose Oramas , Tinne Tuytelaars

Deep Learning has become a very valuable tool in different fields, and no one doubts the learning capacity of these models. Nevertheless, since Deep Learning models are often seen as black boxes due to their lack of interpretability, there…

Machine Learning · Computer Science 2021-04-23 Jokin Labaien , Ekhi Zugasti , Xabier De Carlos

Graph Neural Networks (GNNs) perform well in community detection and molecule classification. Counterfactual Explanations (CE) provide counter-examples to overcome the transparency limitations of black-box models. Due to the growing…

Machine Learning · Computer Science 2024-06-12 Mario Alfonso Prado-Romero , Bardh Prenkaj , Giovanni Stilo , Fosca Giannotti
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