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Detecting and rejecting unknown out-of-distribution (OOD) samples is critical for deployed neural networks to void unreliable predictions. In real-world scenarios, however, the efficacy of existing OOD detection methods is often impeded by…

Computer Vision and Pattern Recognition · Computer Science 2024-11-01 Kai Liu , Zhihang Fu , Sheng Jin , Chao Chen , Ze Chen , Rongxin Jiang , Fan Zhou , Yaowu Chen , Jieping Ye

More than 10.7% of people aged 65 and older are affected by Alzheimer's disease. Early diagnosis and treatment are crucial as most Alzheimer's patients are unaware of having it until the effects become detrimental. AI has been known to use…

Image and Video Processing · Electrical Eng. & Systems 2023-09-19 Audrey Paleczny , Shubham Parab , Maxwell Zhang

The ability to detect unfamiliar or unexpected images is essential for safe deployment of computer vision systems. In the context of classification, the task of detecting images outside of a model's training domain is known as…

Computer Vision and Pattern Recognition · Computer Science 2024-04-03 Galadrielle Humblot-Renaux , Sergio Escalera , Thomas B. Moeslund

Machine learning models deployed on medical imaging tasks must be equipped with out-of-distribution detection capabilities in order to avoid erroneous predictions. It is unsure whether out-of-distribution detection models reliant on deep…

Computer Vision and Pattern Recognition · Computer Science 2022-06-28 Sebastian G. Popescu , David J. Sharp , James H. Cole , Konstantinos Kamnitsas , Ben Glocker

Out-of-distribution detection is an important capability that has long eluded vanilla neural networks. Deep Neural networks (DNNs) tend to generate over-confident predictions when presented with inputs that are significantly…

Machine Learning · Computer Science 2022-02-24 Sumedh A Sontakke , Buvaneswari Ramanan , Laurent Itti , Thomas Woo

To detect distribution shifts and improve model safety, many out-of-distribution (OOD) detection methods rely on the predictive uncertainty or features of supervised models trained on in-distribution data. In this paper, we critically…

Machine Learning · Computer Science 2025-07-03 Yucen Lily Li , Daohan Lu , Polina Kirichenko , Shikai Qiu , Tim G. J. Rudner , C. Bayan Bruss , Andrew Gordon Wilson

Detecting out-of-distribution examples is important for safety-critical machine learning applications such as detecting novel biological phenomena and self-driving cars. However, existing research mainly focuses on simple small-scale…

Computer Vision and Pattern Recognition · Computer Science 2022-05-17 Dan Hendrycks , Steven Basart , Mantas Mazeika , Andy Zou , Joe Kwon , Mohammadreza Mostajabi , Jacob Steinhardt , Dawn Song

Machine learning methods must be trusted to make appropriate decisions in real-world environments, even when faced with out-of-distribution (OOD) samples. Many current approaches simply aim to detect OOD examples and alert the user when an…

Machine Learning · Computer Science 2022-09-13 Randolph Linderman , Jingyang Zhang , Nathan Inkawhich , Hai Li , Yiran Chen

Deep neural networks suffer from the overconfidence issue in the open world, meaning that classifiers could yield confident, incorrect predictions for out-of-distribution (OOD) samples. Thus, it is an urgent and challenging task to detect…

Computer Vision and Pattern Recognition · Computer Science 2022-04-12 Qiuyu Zhu , Guohui Zheng , Yingying Yan

Out-of-distribution recognition forms an important and well-studied problem in deep learning, with the goal to filter out samples that do not belong to the distribution on which a network has been trained. The conclusion of this paper is…

Machine Learning · Computer Science 2025-06-13 Tejaswi Kasarla , Max van Spengler , Pascal Mettes

The recent achievements of Deep Learning rely on the test data being similar in distribution to the training data. In an ideal case, Deep Learning models would achieve Out-of-Distribution (OoD) Generalization, i.e. reliably make predictions…

Image and Video Processing · Electrical Eng. & Systems 2021-09-07 Antoine Sanner , Camila Gonzalez , Anirban Mukhopadhyay

Deep neural networks have achieved great success in classification tasks during the last years. However, one major problem to the path towards artificial intelligence is the inability of neural networks to accurately detect samples from…

Machine Learning · Computer Science 2021-03-16 Aristotelis-Angelos Papadopoulos , Mohammad Reza Rajati , Nazim Shaikh , Jiamian Wang

Despite their success, Machine Learning (ML) models do not generalize effectively to data not originating from the training distribution. To reliably employ ML models in real-world healthcare systems and avoid inaccurate predictions on…

Machine Learning · Computer Science 2023-09-29 Mohammad Azizmalayeri , Ameen Abu-Hanna , Giovanni Ciná

Out-of-distribution (OOD) detection is essential for ensuring the reliability of deep learning models in medical imaging applications. This work is motivated by the observation that class activation maps (CAMs) for in-distribution (ID) data…

Computer Vision and Pattern Recognition · Computer Science 2025-05-14 Yu-Jen Chen , Xueyang Li , Yiyu Shi , Tsung-Yi Ho

Out-of-distribution (OOD) detection is essential for building reliable AI systems, as models that produce outputs for invalid inputs cannot be trusted. Although deep learning (DL) is often assumed to outperform traditional machine learning…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Jihyeon Baek , Seunghoon Lee , Gitaek Kwon , Doohyun Park

To classify in-distribution samples, deep neural networks explore strongly label-related information and discard weakly label-related information according to the information bottleneck. Out-of-distribution samples drawn from distributions…

Machine Learning · Computer Science 2023-08-29 Zhilin Zhao , Longbing Cao

Deep neural networks are known to achieve superior results in classification tasks. However, it has been recently shown that they are incapable to detect examples that are generated by a distribution which is different than the one they…

Machine Learning · Computer Science 2019-12-09 Aristotelis-Angelos Papadopoulos , Nazim Shaikh , Mohammad Reza Rajati

Avoiding out-of-distribution (OOD) data is critical for training supervised machine learning models in the medical imaging domain. Furthermore, obtaining labeled medical data is difficult and expensive since it requires expert annotators…

Computer Vision and Pattern Recognition · Computer Science 2022-10-05 Suraj Kothawade , Akshit Srivastava , Venkat Iyer , Ganesh Ramakrishnan , Rishabh Iyer

Deep Learning models perform unreliably when the data comes from a distribution different from the training one. In critical applications such as medical imaging, out-of-distribution (OOD) detection methods help to identify such data…

Image and Video Processing · Electrical Eng. & Systems 2023-06-26 Anton Vasiliuk , Daria Frolova , Mikhail Belyaev , Boris Shirokikh

When deployed for risk-sensitive tasks, deep neural networks must be able to detect instances with labels from outside the distribution for which they were trained. In this paper we present a novel framework to benchmark the ability of…

Machine Learning · Computer Science 2023-02-24 Ido Galil , Mohammed Dabbah , Ran El-Yaniv