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Objective: Gadolinium-based contrast agents (GBCAs) are commonly employed with T1w MRI to enhance lesion visualization but are restricted in patients at risk of nephrogenic systemic fibrosis and variations in GBCA administration can…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Zach Eidex , Mojtaba Safari , Jie Ding , Richard Qiu , Justin Roper , David Yu , Hui-Kuo Shu , Zhen Tian , Hui Mao , Xiaofeng Yang

This study leverages convolutional neural networks to enhance the temporal resolution of 3D angiography in intracranial aneurysms focusing on the reconstruction of volumetric contrast data from sparse and limited projections. Three…

The dose of X-ray radiation and the scanning time are crucial factors in computed tomography (CT) for clinical applications. In this work, we introduce a multi-source static CT imaging system designed to rapidly acquire sparse view and…

Medical Physics · Physics 2025-01-03 Ziju Shen , Haimiao Zhang , Bin Dong , Jun Qiu , Yunxiang Li , Zhili Cui

Computational imaging plays a pivotal role in determining hidden information from sparse measurements. A robust inverse solver is crucial to fully characterize the uncertainty induced by these measurements, as it allows for the estimation…

Computer Vision and Pattern Recognition · Computer Science 2023-11-17 Sirui Bi , Victor Fung , Jiaxin Zhang

The resurgence of deep neural networks has created an alternative pathway for low-dose computed tomography denoising by learning a nonlinear transformation function between low-dose CT (LDCT) and normal-dose CT (NDCT) image pairs. However,…

Image and Video Processing · Electrical Eng. & Systems 2022-11-04 Sutanu Bera , Prabir Kumar Biswas

Traditional model-based image reconstruction (MBIR) methods combine forward and noise models with simple object priors. Recent machine learning methods for image reconstruction typically involve supervised learning or unsupervised learning,…

Signal Processing · Electrical Eng. & Systems 2023-03-13 Siqi Ye , Zhipeng Li , Michael T. McCann , Yong Long , Saiprasad Ravishankar

Recent years have witnessed growing interest in machine learning-based models and techniques for low-dose X-ray CT (LDCT) imaging tasks. The methods can typically be categorized into supervised learning methods and unsupervised or…

Machine Learning · Computer Science 2019-10-29 Zhipeng Li , Siqi Ye , Yong Long , Saiprasad Ravishankar

Purpose: Cone-beam CT (CBCT) plays an important role in image guided radiation therapy (IGRT). However, the large radiation dose from serial CBCT scans in most IGRT procedures raises a clinical concern, especially for pediatric patients who…

Medical Physics · Physics 2015-05-18 Xun Jia , Yifei Lou , Ruijiang Li , William Y. Song , Steve B. Jiang

Computational fluid dynamics (CFD) can be used for evaluation of hemodynamics. However, its routine use is limited by labor-intensive manual segmentation, CFD mesh creation, and time-consuming simulation. This study aims to train a deep…

Computer Vision and Pattern Recognition · Computer Science 2025-02-18 Tina Yao , Endrit Pajaziti , Michael Quail , Silvia Schievano , Jennifer A Steeden , Vivek Muthurangu

Background: Perfusion computed tomography (CT) images the dynamics of a contrast agent through the body over time, and is one of the highest X-ray dose scans in medical imaging. Recently, a theoretically justified reconstruction algorithm…

Medical Physics · Physics 2026-02-04 Namhoon Kim , Ashwin Pananjady , Amir Pourmorteza , Sara Fridovich-Keil

Deep learning methods for accelerated MRI achieve state-of-the-art results but largely ignore additional speedups possible with noncartesian sampling trajectories. To address this gap, we created a generative diffusion model-based…

Artificial Intelligence · Computer Science 2024-10-02 Trevor J. Chan , Chamith S. Rajapakse

Background: Image reconstruction from highly undersampled 4D flow MRI data can be very time consuming and may result in significant underestimation of velocities depending on regularization, thereby limiting the applicability of the method.…

Medical Physics · Physics 2025-04-01 Luuk Jacobs , Marco Piccirelli , Valery Vishnevskiy , Sebastian Kozerke

Accelerated magnetic resonance imaging involves reconstructing fully sampled images from undersampled k-space measurements. Current state-of-the-art approaches have mainly focused on either end-to-end supervised training inspired by…

Image and Video Processing · Electrical Eng. & Systems 2025-02-25 Xinzhe Luo , Yingzhen Li , Chen Qin

Ultrasound computed tomography (USCT) is a promising technique that achieves superior medical imaging reconstruction resolution by fully leveraging waveform information, outperforming conventional ultrasound methods. Despite its advantages,…

Image and Video Processing · Electrical Eng. & Systems 2024-07-23 Yi Sheng , Hanchen Wang , Yipei Liu , Junhuan Yang , Weiwen Jiang , Youzuo Lin , Lei Yang

To correct for respiratory motion in PET imaging, an interpretable and unsupervised deep learning technique, FlowNet-PET, was constructed. The network was trained to predict the optical flow between two PET frames from different breathing…

Image and Video Processing · Electrical Eng. & Systems 2022-08-04 Teaghan O'Briain , Carlos Uribe , Kwang Moo Yi , Jonas Teuwen , Ioannis Sechopoulos , Magdalena Bazalova-Carter

Reconstructing 3D scenes from sparse viewpoints is a long-standing challenge with wide applications. Recent advances in feed-forward 3D Gaussian sparse-view reconstruction methods provide an efficient solution for real-time novel view…

Computer Vision and Pattern Recognition · Computer Science 2025-06-05 Yang Xiao , Guoan Xu , Qiang Wu , Wenjing Jia

Noise in low-dose computed tomography (LDCT) can obscure important diagnostic details. While deep learning offers powerful denoising, supervised methods require impractical paired data, and self-supervised alternatives often use opaque,…

Image and Video Processing · Electrical Eng. & Systems 2026-02-19 Yipeng Sun , Linda-Sophie Schneider , Siyuan Mei , Jinhua Wang , Ge Hu , Mingxuan Gu , Chengze Ye , Fabian Wagner , Lan Song , Siming Bayer , Andreas Maier

Score-based diffusion models have significantly advanced generative deep learning for image processing. Measurement conditioned models have also been applied to inverse problems such as CT reconstruction. However, the conventional approach,…

Medical Physics · Physics 2025-02-24 Matthew Tivnan , Dufan Wu , Quanzheng Li

Four-dimensional computed tomography (4DCT) has been widely used in cancer radiotherapy for accurate target delineation and motion measurement for tumors in thorax and upper abdomen areas. However, 4DCT simulation is associated with much…

Medical Physics · Physics 2015-05-19 Zhen Tian , Xun Jia , Steve B. Jiang

Photon counting spectral CT (PCCT) can produce reconstructed attenuation maps in different energy channels, reflecting energy properties of the scanned object. Due to the limited photon numbers and the non-ideal detector response of each…

Image and Video Processing · Electrical Eng. & Systems 2022-01-27 Chaoyang Zhang , Shaojie Chang , Ti Bai , Xi Chen
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