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Individuals who suffer anterior cruciate ligament (ACL) injury are at higher risk of developing knee osteoarthritis (OA) and almost 50% display symptoms 10 to 20 years post injury. Anterior cruciate ligament reconstruction (ACLR) often does…

Computational Engineering, Finance, and Science · Computer Science 2015-08-19 Abhijit Chandra , Oliva Kar , Kuan-Chuen Wu , Michelle Hall , Jason Gillette

Clinical decision-making is a feedback system where risk estimates influence treatment, which in turn changes disease trajectories, and both shape clinicians' measurement practices. Static prediction often fails clinically: models trained…

Artificial Intelligence · Computer Science 2026-05-19 Pujun Feng , Xiaoyu Guo , Seyed Ehsan Saffari , Min Hun Lee , Siew-Kei Lam , Erik Cambria , Xibin Sun , Yangtao Zhou , Tong Yang , Xiaoyu Zhang , Tao Tan , Yue Sun , Bin Cui

The ability to predict the future trajectory of a patient is a key step toward the development of therapeutics for complex diseases such as Alzheimer's disease (AD). However, most machine learning approaches developed for prediction of…

Imaging features of knee articular cartilage have been shown to be potential imaging biomarkers for knee osteoarthritis. Despite recent methodological advancements in image analysis techniques like image segmentation, registration, and…

Image and Video Processing · Electrical Eng. & Systems 2024-09-12 Yongcheng Yao , Weitian Chen

Climate and weather prediction traditionally relies on complex numerical simulations of atmospheric physics. Deep learning approaches, such as transformers, have recently challenged the simulation paradigm with complex network forecasts.…

Artificial Intelligence · Computer Science 2024-04-17 Yogesh Verma , Markus Heinonen , Vikas Garg

Knee osteoarthritis (OA) is one of the most common musculoskeletal disorders and requires early-stage diagnosis. Nowadays, the deep convolutional neural networks have achieved greatly in the computer-aided diagnosis field. However, the…

Image and Video Processing · Electrical Eng. & Systems 2020-10-13 Jiayu Huo , Liping Si , Xi Ouyang , Kai Xuan , Weiwu Yao , Zhong Xue , Qian Wang , Dinggang Shen , Lichi Zhang

This research paper explores the classification of knee osteoarthritis (OA) severity levels using advanced computer vision models and augmentation techniques. The study investigates the effectiveness of data preprocessing, including…

Prediction of the future trajectory of a disease is an important challenge for personalized medicine and population health management. However, many complex chronic diseases exhibit large degrees of heterogeneity, and furthermore there is…

Machine Learning · Statistics 2016-08-17 Joseph Futoma , Mark Sendak , C. Blake Cameron , Katherine Heller

Knee osteoarthritis (KOA), a common form of arthritis that causes physical disability, has become increasingly prevalent in society. Employing computer-aided techniques to automatically assess the severity and progression of KOA can greatly…

Image and Video Processing · Electrical Eng. & Systems 2024-08-01 Wenhua Wu , Kun Hu , Wenxi Yue , Wei Li , Milena Simic , Changyang Li , Wei Xiang , Zhiyong Wang

Motion forecasts of road users (i.e., agents) vary in complexity depending on the number of agents, scene constraints, and interactions. In particular, the output space of joint trajectory distributions grows exponentially with the number…

Computer Vision and Pattern Recognition · Computer Science 2026-04-30 Royden Wagner , Omer Sahin Tas , Felix Hauser , Marlon Steiner , Dominik Strutz , Abhishek Vivekanandan , Jaime Villa , Yinzhe Shen , Carlos Fernandez , Christoph Stiller

Predicting the motion of multiple agents is necessary for planning in dynamic environments. This task is challenging for autonomous driving since agents (e.g. vehicles and pedestrians) and their associated behaviors may be diverse and…

Deep learning provides an excellent avenue for optimizing diagnosis and patient monitoring for clinical-based applications, which can critically enhance the response time to the onset of various conditions. For cardiovascular disease, one…

Machine Learning · Computer Science 2023-02-23 Ankur Samanta , Mark Karlov , Meghna Ravikumar , Christian McIntosh Clarke , Jayakumar Rajadas , Kaveh Hassani

Predicting pedestrian motion trajectories is crucial for path planning and motion control of autonomous vehicles. Accurately forecasting crowd trajectories is challenging due to the uncertain nature of human motions in different…

Computer Vision and Pattern Recognition · Computer Science 2024-01-11 Yu Liu , Yuexin Zhang , Kunming Li , Yongliang Qiao , Stewart Worrall , You-Fu Li , He Kong

The fast-growing techniques of measuring and fusing multi-modal biomedical signals enable advanced motor intent decoding schemes of lowerlimb exoskeletons, meeting the increasing demand for rehabilitative or assistive applications of…

Signal Processing · Electrical Eng. & Systems 2021-03-24 Chunzhi Yi , Feng Jiang , Shengping Zhang , Hao Guo , Chifu Yang , Zhen Ding , Baichun Wei , Xiangyuan Lan , Huiyu Zhou

Predicting disease trajectories from electronic health records (EHRs) is a complex task due to major challenges such as data non-stationarity, high granularity of medical codes, and integration of multimodal data. EHRs contain both…

Machine Learning · Computer Science 2025-02-26 Sifal Klioui , Sana Sellami , Youssef Trardi

Clinical data from electronic medical records, registries or trials provide a large source of information to apply machine learning methods in order to foster precision medicine, e.g. by finding new disease phenotypes or performing…

Machine Learning · Computer Science 2020-08-17 Maria Hügle , Gabriel Kalweit , Thomas Huegle , Joschka Boedecker

Trajectory prediction is crucial for autonomous driving, enabling vehicles to navigate safely by anticipating the movements of surrounding road users. However, current deep learning models often lack trustworthiness as their predictions can…

Background:Subject-specific finite element analysis accurately characterizes knee joint mechanics but is computationally expensive. Deep surrogate models provide a rapid alternative, yet their generalization across subjects under limited…

Quantitative Methods · Quantitative Biology 2026-01-14 Zhengye Pan , Jianwei Zuo , Jiajia Luo

Deep neural networks have been widely studied for predicting a medical condition, such as total knee replacement (TKR). It has shown that data of different modalities, such as imaging data, clinical variables and demographic information,…

Computer Vision and Pattern Recognition · Computer Science 2023-03-27 Xinwen Liu , Jing Wang , S. Kevin Zhou , Craig Engstrom , Shekhar S. Chandra

Predicting lower limb motion intent is vital for controlling exoskeleton robots and prosthetic limbs. Surface electromyography (sEMG) attracts increasing attention in recent years as it enables ahead-of-time prediction of motion intentions…