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Deep learning models have driven significant progress in predicting protein function and interactions at the protein level. While these advancements have been invaluable for many biological applications such as enzyme engineering and…

Machine Learning · Computer Science 2025-05-20 Yang Tan , Wenrui Gou , Bozitao Zhong , Liang Hong , Huiqun Yu , Bingxin Zhou

Identifying protein functional sites (PFSs) and protein-ligand interactions (PLIs) are critically important in understanding the protein function and the involved biochemical reactions. As large amount of unknown proteins are quickly…

Biomolecules · Quantitative Biology 2017-01-30 Dengming Ming , Min Han , Xiongbo An

This study presents a novel method for improving rice disease classification using 8 different convolutional neural network (CNN) algorithms, which will further the field of precision agriculture. Tkinter-based application that offers…

Computer Vision and Pattern Recognition · Computer Science 2024-10-04 Biplov Paneru , Bishwash Paneru , Krishna Bikram Shah

Significant advances have been made towards building accurate automatic segmentation systems for a variety of biomedical applications using machine learning. However, the performance of these systems often degrades when they are applied on…

Predicting the responses of a cell under perturbations may bring important benefits to drug discovery and personalized therapeutics. In this work, we propose a novel graph variational Bayesian causal inference framework to predict a cell's…

Multivariate time series (MTS) forecasting is an essential problem in many fields. Accurate forecasting results can effectively help decision-making. To date, many MTS forecasting methods have been proposed and widely applied. However,…

Machine Learning · Computer Science 2021-12-16 Ziheng Duan , Haoyan Xu , Yida Huang , Jie Feng , Yueyang Wang

Accurate computational identification of promoters remains a challenge as these key DNA regulatory regions have variable structures composed of functional motifs that provide gene specific initiation of transcription. In this paper we…

Genomics · Quantitative Biology 2016-10-04 Victor Solovyev , Ramzan Umarov

Constituency parsing and nested named entity recognition (NER) are similar tasks since they both aim to predict a collection of nested and non-crossing spans. In this work, we cast nested NER to constituency parsing and propose a novel…

Computation and Language · Computer Science 2022-03-10 Songlin Yang , Kewei Tu

Unlike widely used Named Entity Recognition (NER) data sets in generic domains, biomedical NER data sets often contain mentions consisting of discontinuous spans. Conventional sequence tagging techniques encode Markov assumptions that are…

Computation and Language · Computer Science 2020-04-29 Xiang Dai , Sarvnaz Karimi , Ben Hachey , Cecile Paris

Dynamic prediction of causal effects under different treatment regimes conditional on an individual's characteristics and longitudinal history is an essential problem in precision medicine. This is challenging in practice because outcomes…

Methodology · Statistics 2023-03-07 Yizhen Xu , Jisoo Kim , Laura K. Hummers , Ami A. Shah , Scott Zeger

Irregularly measured time series are common in many of the applied settings in which time series modelling is a key statistical tool, including medicine. This provides challenges in model choice, often necessitating imputation or similar…

In many recommender systems, users and items are associated with attributes, and users show preferences to items. The attribute information describes users'(items') characteristics and has a wide range of applications, such as user…

Information Retrieval · Computer Science 2020-05-26 Le Wu , Yonghui Yang , Kun Zhang , Richang Hong , Yanjie Fu , Meng Wang

Dependency grammar induction is the task of learning dependency syntax without annotated training data. Traditional graph-based models with global inference achieve state-of-the-art results on this task but they require $O(n^3)$ run time.…

Computation and Language · Computer Science 2018-11-15 Bowen Li , Jianpeng Cheng , Yang Liu , Frank Keller

Unconstrained handwritten text recognition is a major step in most document analysis tasks. This is generally processed by deep recurrent neural networks and more specifically with the use of Long Short-Term Memory cells. The main drawbacks…

Computer Vision and Pattern Recognition · Computer Science 2020-12-10 Denis Coquenet , Clément Chatelain , Thierry Paquet

An invasive species of grass known as "buffelgrass" contributes to severe wildfires and biodiversity loss in the Southwest United States. We tackle the problem of predicting buffelgrass "green-ups" (i.e. readiness for herbicidal treatment).…

Computer Vision and Pattern Recognition · Computer Science 2023-10-03 Lucas Rosenblatt , Bin Han , Erin Posthumus , Theresa Crimmins , Bill Howe

Transition-based parsers implemented with Pointer Networks have become the new state of the art in dependency parsing, excelling in producing labelled syntactic trees and outperforming graph-based models in this task. In order to further…

Computation and Language · Computer Science 2020-05-29 Daniel Fernández-González , Carlos Gómez-Rodríguez

The characterization of drug-protein interactions is crucial in the high-throughput screening for drug discovery. The deep learning-based approaches have attracted attention because they can predict drug-protein interactions without…

Machine Learning · Computer Science 2020-12-22 QHwan Kim , Joon-Hyuk Ko , Sunghoon Kim , Nojun Park , Wonho Jhe

Real-time sequence identification is a core use-case of artificial neural networks (ANNs), ranging from recognizing temporal events to identifying verification codes. Existing methods apply recurrent neural networks, which suffer from…

The Session-Based Recommendation System aims to predict the user's next click based on their previous session sequence. The current studies generally learn user preferences according to the transitions of items in the user's session…

Information Retrieval · Computer Science 2023-10-06 Jinpeng Chen , Haiyang Li , Xudong Zhang , Fan Zhang , Senzhang Wang , Kaimin Wei , Jiaqi Ji

Gene regulatory networks (GRNs) control cellular function and decision making during tissue development and homeostasis. Mathematical tools based on dynamical systems theory are often used to model these networks, but the size and…

Molecular Networks · Quantitative Biology 2018-03-16 Edgar Herrera-Delgado , Ruben Perez-Carrasco , James Briscoe , Peter Sollich