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Learning good representations involves capturing the diverse ways in which data samples relate. Contrastive loss - an objective matching related samples - underlies methods from self-supervised to multimodal learning. Contrastive losses,…

Computer Vision and Pattern Recognition · Computer Science 2024-09-13 Vlad Sobal , Mark Ibrahim , Randall Balestriero , Vivien Cabannes , Diane Bouchacourt , Pietro Astolfi , Kyunghyun Cho , Yann LeCun

Learning Electronic Health Records (EHRs) representation is a preeminent yet under-discovered research topic. It benefits various clinical decision support applications, e.g., medication outcome prediction or patient similarity search.…

Machine Learning · Computer Science 2024-02-22 Hao-Ren Yao , Nairen Cao , Katina Russell , Der-Chen Chang , Ophir Frieder , Jeremy Fineman

Clinical outcome prediction based on the Electronic Health Record (EHR) plays a crucial role in improving the quality of healthcare. Conventional deep sequential models fail to capture the rich temporal patterns encoded in the longand…

Machine Learning · Computer Science 2019-08-27 Luchen Liu , Haoran Li , Zhiting Hu , Haoran Shi , Zichang Wang , Jian Tang , Ming Zhang

The rapid growth of Electronic Health Records (EHRs), as well as the accompanied opportunities in Data-Driven Healthcare (DDH), has been attracting widespread interests and attentions. Recent progress in the design and applications of deep…

Machine Learning · Computer Science 2017-09-07 Zhengping Che , Yu Cheng , Shuangfei Zhai , Zhaonan Sun , Yan Liu

Contrastive representation learning (CRL) underpins many modern foundation models. Despite recent theoretical progress, existing analyses suffer from several key limitations: (i) the statistical consistency of CRL remains poorly understood;…

Machine Learning · Computer Science 2026-05-29 Yuanfan Li , Xiyuan Wei , Tianbao Yang , Yiming Ying

Datasets for biosignals, such as electroencephalogram (EEG) and electrocardiogram (ECG), often have noisy labels and have limited number of subjects (<100). To handle these challenges, we propose a self-supervised approach based on…

Machine Learning · Computer Science 2020-07-10 Joseph Y. Cheng , Hanlin Goh , Kaan Dogrusoz , Oncel Tuzel , Erdrin Azemi

An electrocardiogram (ECG) is a widely used, cost-effective tool for detecting electrical abnormalities in the heart. However, it cannot directly measure functional parameters, such as ventricular volumes and ejection fraction, which are…

Image and Video Processing · Electrical Eng. & Systems 2025-06-27 Alexander Selivanov , Philip Müller , Özgün Turgut , Nil Stolt-Ansó , Daniel Rückert

Learning representations unaffected by superficial characteristics is important to ensure that shifts in these characteristics at test time do not compromise downstream prediction performance. For instance, in healthcare applications, we…

Machine Learning · Computer Science 2025-07-28 Minghui Sun , Benjamin A. Goldstein , Matthew M. Engelhard

Contrastive learning predicts whether two images belong to the same category by training a model to make their feature representations as close or as far away as possible. In this paper, we rethink how to mine samples in contrastive…

Computer Vision and Pattern Recognition · Computer Science 2023-11-02 Hengkui Dong , Xianzhong Long , Yun Li

Evaluating the clinical similarities between pairwise patients is a fundamental problem in healthcare informatics. A proper patient similarity measure enables various downstream applications, such as cohort study and treatment comparative…

Machine Learning · Statistics 2019-02-12 Zihao Zhu , Changchang Yin , Buyue Qian , Yu Cheng , Jishang Wei , Fei Wang

Recently, various contrastive learning techniques have been developed to categorize time series data and exhibit promising performance. A general paradigm is to utilize appropriate augmentations and construct feasible positive samples such…

Machine Learning · Computer Science 2024-10-11 Qianying Ren , Dongsheng Luo , Dongjin Song

Stimulus-evoked EEG data has a notoriously low signal-to-noise ratio and high inter-subject variability. We propose a novel paradigm for the self-supervised extraction of stimulus-related brain response data: a model is trained to extract…

Neurons and Cognition · Quantitative Biology 2024-05-15 Bernd Accou , Hugo Van hamme , Tom Francart

Traditional supervised learning with deep neural networks requires a tremendous amount of labelled data to converge to a good solution. For 3D medical images, it is often impractical to build a large homogeneous annotated dataset for a…

Contrastive pretraining can substantially increase model generalisation and downstream performance. However, the quality of the learned representations is highly dependent on the data augmentation strategy applied to generate positive…

Computer Vision and Pattern Recognition · Computer Science 2025-06-17 Mélanie Roschewitz , Fabio De Sousa Ribeiro , Tian Xia , Galvin Khara , Ben Glocker

Analysis of longitudinal Electronic Health Record (EHR) data is an important goal for precision medicine. Difficulty in applying Machine Learning (ML) methods, either predictive or unsupervised, stems in part from the heterogeneity and…

Quantitative Methods · Quantitative Biology 2022-04-18 Alan D. Kaplan , Uttara Tipnis , Jean C. Beckham , Nathan A. Kimbrel , David W. Oslin , Benjamin H. McMahon

Large medical imaging datasets can be cheaply and quickly annotated with low-confidence, weak labels (e.g., radiological scores). Access to high-confidence labels, such as histology-based diagnoses, is rare and costly. Pretraining…

Computer Vision and Pattern Recognition · Computer Science 2023-09-20 Emma Sarfati , Alexandre Bône , Marc-Michel Rohé , Pietro Gori , Isabelle Bloch

Medical images and reports offer invaluable insights into patient health. The heterogeneity and complexity of these data hinder effective analysis. To bridge this gap, we investigate contrastive learning models for cross-domain retrieval,…

Computer Vision and Pattern Recognition · Computer Science 2025-01-17 Demetrio Deanda , Yuktha Priya Masupalli , Jeong Yang , Young Lee , Zechun Cao , Gongbo Liang

Unsupervised learning has been a long-standing goal of machine learning and is especially important for medical image analysis, where the learning can compensate for the scarcity of labeled datasets. A promising subclass of unsupervised…

Image and Video Processing · Electrical Eng. & Systems 2021-09-09 Ozan Ciga , Tony Xu , Anne L. Martel

Electrocardiogram (ECG) analysis is foundational for cardiovascular disease diagnosis, yet the performance of deep learning models is often constrained by limited access to annotated data. Self-supervised contrastive learning has emerged as…

Machine Learning · Computer Science 2025-08-22 Yi Yuan , Joseph Van Duyn , Runze Yan , Zhuoyi Huang , Sulaiman Vesal , Sergey Plis , Xiao Hu , Gloria Hyunjung Kwak , Ran Xiao , Alex Fedorov

The healthcare industry generates troves of unlabelled physiological data. This data can be exploited via contrastive learning, a self-supervised pre-training method that encourages representations of instances to be similar to one another.…

Machine Learning · Computer Science 2021-05-18 Dani Kiyasseh , Tingting Zhu , David A. Clifton