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Current techniques in sequencing a genome allow a service provider (e.g. a sequencing company) to have full access to the genome information, and thus the privacy of individuals regarding their lifetime secret is violated. In this paper, we…

Genomics · Quantitative Biology 2018-11-28 Ali Gholami , Mohammad Ali Maddah-Ali , Seyed Abolfazl Motahari

Preserving the privacy and security of big data in the context of cloud computing, while maintaining a certain level of efficiency of its processing remains to be a subject, open for improvement. One of the most popular applications…

Cryptography and Security · Computer Science 2022-02-02 Ş. S. Mağara , C. Yıldırım , F. Yaman , B. Dilekoğlu , F. R. Tutaş , E. Öztürk , K. Kaya , Ö. Taştan , E. Savaş

DNA motif discovery is an important issue in gene research, which aims to identify transcription factor binding sites (i.e., motifs) in DNA sequences to reveal the mechanisms that regulate gene expression. However, the phenomenon of data…

Cryptography and Security · Computer Science 2023-04-05 Yao Chen , Wensheng Gan , Gengsen Huang , Yongdong Wu , Philip S. Yu

Graph embedding has become a powerful tool for learning latent representations of nodes in a graph. Despite its superior performance in various graph-based machine learning tasks, serious privacy concerns arise when the graph data contains…

Cryptography and Security · Computer Science 2024-08-06 Zening Li , Rong-Hua Li , Meihao Liao , Fusheng Jin , Guoren Wang

In this paper, we introduce ACE, a consent-embedded searchable encryption scheme. ACE enables dynamic consent management by supporting the physical deletion of associated data at the time of consent revocation. This ensures instant real…

Cryptography and Security · Computer Science 2023-07-25 Sara Jafarbeiki , Amin Sakzad , Ron Steinfeld , Shabnam Kasra Kermanshahi , Chandra Thapa , Yuki Kume

Deep learning is widely applied to modern problems through neural networks, but the growing computational and energy demands of these models have driven interest in more efficient approaches. Spiking Neural Networks (SNNs), the third…

Cryptography and Security · Computer Science 2025-11-18 Mahitha Pulivathi , Ana Fontes Rodrigues , Isibor Kennedy Ihianle , Andreas Oikonomou , Srinivas Boppu , Pedro Machado

Quantum homomorphic encryption (QHE) is an encryption method that allows quantum computation to be performed on one party's private data with the program provided by another party, without revealing much information about the data nor about…

Quantum Physics · Physics 2019-08-02 Li Yu

In this paper, we propose a new biometric verification and template protection system which we call the THRIVE system. The system includes novel enrollment and authentication protocols based on threshold homomorphic cryptosystem where the…

Cryptography and Security · Computer Science 2015-09-02 Cagatay Karabat , Mehmet Sabir Kiraz , Hakan Erdogan , Erkay Savas

While NLP models significantly impact our lives, there are rising concerns about privacy invasion. Although federated learning enhances privacy, attackers may recover private training data by exploiting model parameters and gradients.…

Artificial Intelligence · Computer Science 2024-10-23 Mengjiao Zhang , Jia Xu

Portable genome sequencing technology is revolutionizing genomic research by providing a faster, more flexible method of sequencing DNA and RNA [1, 2]. The unprecedented shift from bulky stand-alone benchtop equipment confined in a…

Cryptography and Security · Computer Science 2024-07-18 Carson Stillman , Jonathan E. Bravo , Christina Boucher , Sara Rampazzi

One way of investigating how genes affect human traits would be with a genome-wide association study (GWAS). Genetic markers, known as single-nucleotide polymorphism (SNP), are used in GWAS. This raises privacy and security concerns as…

Applications · Statistics 2019-08-02 Jun Jie Sim , Fook Mun Chan , Shibin Chen , Benjamin Hong Meng Tan , Khin Mi Mi Aung

The rapid advancement of Large Language Models (LLMs) has driven significant progress in Natural Language Interface to Database (NLIDB). However, the widespread adoption of LLMs has raised critical privacy and security concerns. During…

Computation and Language · Computer Science 2025-11-12 Ruiheng Liu , XiaoBing Chen , Jinyu Zhang , Qiongwen Zhang , Yu Zhang , Bailong Yang

Privacy-preserving genomic data sharing is prominent to increase the pace of genomic research, and hence to pave the way towards personalized genomic medicine. In this paper, we introduce ($\epsilon , T$)-dependent local differential…

Cryptography and Security · Computer Science 2021-02-16 Emre Yilmaz , Tianxi Ji , Erman Ayday , Pan Li

Searchable Symmetric Encryption (SSE) allows a data owner to securely outsource its encrypted data to a cloud server while maintaining the ability to search over it and retrieve matched documents. Most existing SSE schemes leak which…

Cryptography and Security · Computer Science 2021-02-22 Zhiwei Shang , Simon Oya , Andreas Peter , Florian Kerschbaum

We present RHODE, a novel system that enables privacy-preserving training of and prediction on Recurrent Neural Networks (RNNs) in a cross-silo federated learning setting by relying on multiparty homomorphic encryption. RHODE preserves the…

Cryptography and Security · Computer Science 2023-05-04 Sinem Sav , Abdulrahman Diaa , Apostolos Pyrgelis , Jean-Philippe Bossuat , Jean-Pierre Hubaux

Personalized privacy becomes critical in deep learning for Trustworthy AI. While Differentially Private Stochastic Gradient Descent (DP-SGD) is widely used in deep learning methods supporting privacy, it provides the same level of privacy…

Machine Learning · Computer Science 2023-05-25 Geon Heo , Junseok Seo , Steven Euijong Whang

Traditional approaches to vector similarity search over encrypted data rely on fully homomorphic encryption (FHE) to enable computation without decryption. However, the substantial computational overhead of FHE makes it impractical for…

Cryptography and Security · Computer Science 2025-02-21 Dongfang Zhao

Self-supervised pre-training methods have brought remarkable breakthroughs in the understanding of text, image, and speech. Recent developments in genomics has also adopted these pre-training methods for genome understanding. However, they…

Machine Learning · Computer Science 2022-04-15 Samuel Cahyawijaya , Tiezheng Yu , Zihan Liu , Tiffany T. W. Mak , Xiaopu Zhou , Nancy Y. Ip , Pascale Fung

In the post-genomic era, large-scale personal DNA sequences are produced and collected for genetic medical diagnoses and new drug discovery, which, however, simultaneously poses serious challenges to the protection of personal genomic…

Cryptography and Security · Computer Science 2017-08-10 Shibiao Wan , Man-Wai Mak , Sun-Yuan Kung

With the reduction of sequencing costs and the pervasiveness of computing devices, genomic data collection is continually growing. However, data collection is highly fragmented and the data is still siloed across different repositories.…

Cryptography and Security · Computer Science 2022-03-14 Leonard Dervishi , Xinyue Wang , Wentao Li , Anisa Halimi , Jaideep Vaidya , Xiaoqian Jiang , Erman Ayday