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Cellular Agent-Based Models are commonly employed to describe a variety biological systems. Over the course of the past years, many modeling tools have emerged which solve particular research questions. In this short opinion piece, we argue…

Cell Behavior · Quantitative Biology 2025-11-18 Jonas Pleyer

Fully leveraging the capabilities of AI agents in software development requires a rethinking of the software ecosystem itself. To this end, this paper outlines the creation of an Agentic Infused Software Ecosystem (AISE), that rests on…

Software Engineering · Computer Science 2026-02-25 Mark Marron

Agent-based modeling (ABM) is a well-established paradigm for simulating complex systems via interactions between constituent entities. Machine learning (ML) refers to approaches whereby statistical algorithms 'learn' from data on their…

Quantitative Methods · Quantitative Biology 2022-11-10 Nikita Sivakumar , Cameron Mura , Shayn M. Peirce

Data is a valuable asset, and sharing it as a product across organizations is key to building comprehensive and useful insights in fields such as science and industry. Before sharing, data often requires transformation to comply with…

Social and Information Networks · Computer Science 2025-03-18 Sepideh Masoudi

As the amount of scientific data continues to grow at ever faster rates, the research community is increasingly in need of flexible computational infrastructure that can support the entirety of the data science lifecycle, including…

Computers and Society · Computer Science 2016-04-12 Robert L. Grossman , Allison Heath , Mark Murphy , Maria Patterson , Walt Wells

Recent advances in large language models (LLMs) have opened new avenues for applying multi-agent systems in very large-scale simulations. However, there remain several challenges when conducting multi-agent simulations with existing…

Multiagent Systems · Computer Science 2024-10-29 Xuchen Pan , Dawei Gao , Yuexiang Xie , Yushuo Chen , Zhewei Wei , Yaliang Li , Bolin Ding , Ji-Rong Wen , Jingren Zhou

Despite the extensive use of the agent technology in the Supply Chain Management field, its integration with Advanced Planning and Scheduling (APS) tools still represents a promising field with several open research questions. Specifically,…

Multiagent Systems · Computer Science 2011-07-19 Luis Antonio de Santa-Eulalia , Sophie D'Amours , Jean-Marc Frayret

Formal modelling of Multi-Agent Systems (MAS) is a challenging task due to high complexity, interaction, parallelism and continuous change of roles and organisation between agents. In this paper we record our research experience on formal…

Multiagent Systems · Computer Science 2010-08-20 Petros Kefalas , Ioanna Stamatopoulou

Data is a precious resource in today's society, and is generated at an unprecedented and constantly growing pace. The need to store, analyze, and make data promptly available to a multitude of users introduces formidable challenges in…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-06-08 Alessandro Margara , Gianpaolo Cugola , Nicolò Felicioni , Stefano Cilloni

Agent-based modeling and simulation has evolved as a powerful tool for modeling complex systems, offering insights into emergent behaviors and interactions among diverse agents. Integrating large language models into agent-based modeling…

Artificial Intelligence · Computer Science 2023-12-20 Chen Gao , Xiaochong Lan , Nian Li , Yuan Yuan , Jingtao Ding , Zhilun Zhou , Fengli Xu , Yong Li

Data is becoming an important central point for making design decisions for most software. Game development is not an exception. As data-driven methods and systems start to populate these environments, a good question is: can we make models…

Human-Computer Interaction · Computer Science 2021-10-13 Jichen Zhu , Magy Seif El-Nasr

Astronomy produces extremely large data sets from ground-based telescopes, space missions, and simulation. The volume and complexity of these rich data sets require new approaches and advanced tools to understand the information contained…

Instrumentation and Methods for Astrophysics · Physics 2014-02-25 Demitri Muna , Eric Huff

To observe how individual behavior shapes a larger community's actions, agent-based modeling and simulation (ABMS) has been widely adopted by researchers in social sciences, economics, and epidemiology. While simulations can be run on…

Social and Information Networks · Computer Science 2025-07-16 Ann Nedime Nese Rende , Tolga Yilmaz , Özgür Ulusoy

Powerful machine learning (ML) models are now readily available online, which creates exciting possibilities for users who lack the deep technical expertise or substantial computing resources needed to develop them. On the other hand, this…

Machine Learning · Computer Science 2025-05-30 Sarah Meiklejohn , Hayden Blauzvern , Mihai Maruseac , Spencer Schrock , Laurent Simon , Ilia Shumailov

Multiscale models provide a unique tool for studying complex processes that study events occurring at different scales across space and time. In the context of biological systems, such models can simulate mechanisms happening at the…

Quantitative Methods · Quantitative Biology 2024-06-27 Marco Ruscone , Andrea Checcoli , Randy Heiland , Emmanuel Barillot , Paul Macklin , Laurence Calzone , Vincent Noël

LLM-based agents are rapidly proliferating, yet the infrastructure for discovering, evaluating, and governing them remains fragmented compared to mature ecosystems like software package registries (e.g., npm) and model hubs (e.g., Hugging…

The current economic crisis has provoked an active response from the interdisciplinary scientific community. As a result many papers suggesting what can be improved in understanding of the complex socio-economics systems were published.…

Physics and Society · Physics 2018-10-17 Aleksejus Kononovicius , Valentas Daniunas

A consistent theme in software experimentation at Microsoft has been solving problems of experimentation at scale for a diverse set of products. Running experiments at scale (i.e., many experiments on many users) has become state of the art…

Applications · Statistics 2019-12-03 Craig Boucher , Ulf Knoblich , Daniel Miller , Sasha Patotski , Amin Saied , Venky Venkateshaiah

Mechanistic simulators are an indispensable tool for epidemiology to explore the behavior of complex, dynamic infections under varying conditions and navigate uncertain environments. Agent-based models (ABMs) are an increasingly popular…

Agent based modelling is a simulation method in which autonomous agents interact with their environment and one another, given a predefined set of rules. It is an integral method for modelling and simulating complex systems, such as…

Multiagent Systems · Computer Science 2022-01-10 George Datseris , Ali R. Vahdati , Timothy C. DuBois