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Clinical diagnosis of the eye is performed over multifarious data modalities including scalar clinical labels, vectorized biomarkers, two-dimensional fundus images, and three-dimensional Optical Coherence Tomography (OCT) scans. Clinical…

Image and Video Processing · Electrical Eng. & Systems 2022-09-23 Mohit Prabhushankar , Kiran Kokilepersaud , Yash-yee Logan , Stephanie Trejo Corona , Ghassan AlRegib , Charles Wykoff

The rising prevalence of vision-threatening retinal diseases poses a significant burden on the global healthcare systems. Deep learning (DL) offers a promising solution for automatic disease screening but demands substantial data.…

Image and Video Processing · Electrical Eng. & Systems 2024-11-18 Ruoyu Chen , Weiyi Zhang , Bowen Liu , Xiaolan Chen , Pusheng Xu , Shunming Liu , Mingguang He , Danli Shi

Retinal imaging has emerged as a powerful, non-invasive modality for detecting and quantifying biomarkers of systemic diseases-ranging from diabetes and hypertension to Alzheimer's disease and cardiovascular disorders but current insights…

Image and Video Processing · Electrical Eng. & Systems 2025-05-28 Tariq M Khan , Toufique Ahmed Soomro , Imran Razzak

In the real world, medical datasets often exhibit a long-tailed data distribution (i.e., a few classes occupy the majority of the data, while most classes have only a limited number of samples), which results in a challenging long-tailed…

Computer Vision and Pattern Recognition · Computer Science 2023-03-22 Lie Ju , Zhen Yu , Lin Wang , Xin Zhao , Xin Wang , Paul Bonnington , Zongyuan Ge

Despite the excitement behind biomedical artificial intelligence (AI), access to high-quality, diverse, and large-scale data - the foundation for modern AI systems - is still a bottleneck to unlocking its full potential. To address this…

The advancement of general medical Multimodal Large Language Models (MLLMs) has shown great potential for building conversational assistants to support clinical diagnosis. However, their adaptation to highly specialized domains such as…

Computer Vision and Pattern Recognition · Computer Science 2026-05-28 Xuanzhao Dong , Wenhui Zhu , Xiwen Chen , Hao Wang , Xin Li , Yujian Xiong , Jiajun Cheng , Jingjing Wang , Xiaobing Yu , Haiyu Wu , Shao Tang , Zhipeng Wang , Langechuan Liu , Shan Lin , Oana Dumitrascu , Yalin Wang

The visual analysis of retinal data contributes to the understanding of a wide range of eye diseases. For the evaluation of cross-sectional studies, ophthalmologists rely on workflows and toolsets established in their work environment. That…

Human-Computer Interaction · Computer Science 2023-01-06 Martin Röhlig , Lars Nonnemann , Hans-Jörg Schulz , Oliver Stachs , Heidrun Schumann

Large multimodal language models (LMMs) have achieved significant success in general domains. However, due to the significant differences between medical images and text and general web content, the performance of LMMs in medical scenarios…

Computer Vision and Pattern Recognition · Computer Science 2023-06-23 Weihao Gao , Zhuo Deng , Zhiyuan Niu , Fuju Rong , Chucheng Chen , Zheng Gong , Wenze Zhang , Daimin Xiao , Fang Li , Zhenjie Cao , Zhaoyi Ma , Wenbin Wei , Lan Ma

We introduce Long-VITA, a simple yet effective large multi-modal model for long-context visual-language understanding tasks. It is adept at concurrently processing and analyzing modalities of image, video, and text over 4K frames or 1M…

Computer Vision and Pattern Recognition · Computer Science 2025-10-29 Yunhang Shen , Chaoyou Fu , Shaoqi Dong , Xiong Wang , Yi-Fan Zhang , Peixian Chen , Mengdan Zhang , Haoyu Cao , Ke Li , Shaohui Lin , Xiawu Zheng , Yan Zhang , Yiyi Zhou , Ran He , Caifeng Shan , Rongrong Ji , Xing Sun

Omnidirectional image (ODI) data is captured with a field-of-view of 360x180, which is much wider than the pinhole cameras and captures richer surrounding environment details than the conventional perspective images. In recent years, the…

Computer Vision and Pattern Recognition · Computer Science 2025-02-18 Hao Ai , Zidong Cao , Lin Wang

Designing Artificial Intelligence (AI) solutions that can operate in real-world situations is a highly complex task. Deploying such solutions in the medical domain is even more challenging. The promise of using AI to improve patient care…

Human-Computer Interaction · Computer Science 2021-10-08 Sagi Schein , Greg Arutiunian , Vitaly Burshtein , Gal Sadeh , Michelle Townshend , Bruce Friedman , Shada Sadr-azodi

Modern medicine generates vast multimodal data across siloed systems, yet no existing model integrates the full breadth and temporal depth of the clinical record into a unified patient representation. We introduce Apollo, a multimodal…

Prior to the deep learning era, shape was commonly used to describe the objects. Nowadays, state-of-the-art (SOTA) algorithms in medical imaging are predominantly diverging from computer vision, where voxel grids, meshes, point clouds, and…

Computer Vision and Pattern Recognition · Computer Science 2025-06-06 Jianning Li , Zongwei Zhou , Jiancheng Yang , Antonio Pepe , Christina Gsaxner , Gijs Luijten , Chongyu Qu , Tiezheng Zhang , Xiaoxi Chen , Wenxuan Li , Marek Wodzinski , Paul Friedrich , Kangxian Xie , Yuan Jin , Narmada Ambigapathy , Enrico Nasca , Naida Solak , Gian Marco Melito , Viet Duc Vu , Afaque R. Memon , Christopher Schlachta , Sandrine De Ribaupierre , Rajnikant Patel , Roy Eagleson , Xiaojun Chen , Heinrich Mächler , Jan Stefan Kirschke , Ezequiel de la Rosa , Patrick Ferdinand Christ , Hongwei Bran Li , David G. Ellis , Michele R. Aizenberg , Sergios Gatidis , Thomas Küstner , Nadya Shusharina , Nicholas Heller , Vincent Andrearczyk , Adrien Depeursinge , Mathieu Hatt , Anjany Sekuboyina , Maximilian Löffler , Hans Liebl , Reuben Dorent , Tom Vercauteren , Jonathan Shapey , Aaron Kujawa , Stefan Cornelissen , Patrick Langenhuizen , Achraf Ben-Hamadou , Ahmed Rekik , Sergi Pujades , Edmond Boyer , Federico Bolelli , Costantino Grana , Luca Lumetti , Hamidreza Salehi , Jun Ma , Yao Zhang , Ramtin Gharleghi , Susann Beier , Arcot Sowmya , Eduardo A. Garza-Villarreal , Thania Balducci , Diego Angeles-Valdez , Roberto Souza , Leticia Rittner , Richard Frayne , Yuanfeng Ji , Vincenzo Ferrari , Soumick Chatterjee , Florian Dubost , Stefanie Schreiber , Hendrik Mattern , Oliver Speck , Daniel Haehn , Christoph John , Andreas Nürnberger , João Pedrosa , Carlos Ferreira , Guilherme Aresta , António Cunha , Aurélio Campilho , Yannick Suter , Jose Garcia , Alain Lalande , Vicky Vandenbossche , Aline Van Oevelen , Kate Duquesne , Hamza Mekhzoum , Jef Vandemeulebroucke , Emmanuel Audenaert , Claudia Krebs , Timo van Leeuwen , Evie Vereecke , Hauke Heidemeyer , Rainer Röhrig , Frank Hölzle , Vahid Badeli , Kathrin Krieger , Matthias Gunzer , Jianxu Chen , Timo van Meegdenburg , Amin Dada , Miriam Balzer , Jana Fragemann , Frederic Jonske , Moritz Rempe , Stanislav Malorodov , Fin H. Bahnsen , Constantin Seibold , Alexander Jaus , Zdravko Marinov , Paul F. Jaeger , Rainer Stiefelhagen , Ana Sofia Santos , Mariana Lindo , André Ferreira , Victor Alves , Michael Kamp , Amr Abourayya , Felix Nensa , Fabian Hörst , Alexander Brehmer , Lukas Heine , Yannik Hanusrichter , Martin Weßling , Marcel Dudda , Lars E. Podleska , Matthias A. Fink , Julius Keyl , Konstantinos Tserpes , Moon-Sung Kim , Shireen Elhabian , Hans Lamecker , Dženan Zukić , Beatriz Paniagua , Christian Wachinger , Martin Urschler , Luc Duong , Jakob Wasserthal , Peter F. Hoyer , Oliver Basu , Thomas Maal , Max J. H. Witjes , Gregor Schiele , Ti-chiun Chang , Seyed-Ahmad Ahmadi , Ping Luo , Bjoern Menze , Mauricio Reyes , Thomas M. Deserno , Christos Davatzikos , Behrus Puladi , Pascal Fua , Alan L. Yuille , Jens Kleesiek , Jan Egger

Optoacoustic (OA) imaging is based on excitation of biological tissues with nanosecond-duration laser pulses followed by subsequent detection of ultrasound waves generated via light-absorption-mediated thermoelastic expansion. OA imaging…

Image and Video Processing · Electrical Eng. & Systems 2023-05-04 Firat Ozdemir , Berkan Lafci , Xosé Luís Deán-Ben , Daniel Razansky , Fernando Perez-Cruz

Artificial intelligence (AI) systems hold great promise to improve healthcare over the next decades. Specifically, AI systems leveraging multiple data sources and input modalities are poised to become a viable method to deliver more…

A patient undergoes multiple examinations in each hospital stay, where each provides different facets of the health status. These assessments include temporal data with varying sampling rates, discrete single-point measurements, therapeutic…

Computer Vision and Pattern Recognition · Computer Science 2025-01-31 Malte Tölle , Mohamad Scharaf , Samantha Fischer , Christoph Reich , Silav Zeid , Christoph Dieterich , Benjamin Meder , Norbert Frey , Philipp Wild , Sandy Engelhardt

An accurate computational model for image quality assessment (IQA) benefits many vision applications, such as image filtering, image processing, and image generation. Although the study of face images is an important subfield in computer…

Computer Vision and Pattern Recognition · Computer Science 2023-08-01 Shaolin Su , Hanhe Lin , Vlad Hosu , Oliver Wiedemann , Jinqiu Sun , Yu Zhu , Hantao Liu , Yanning Zhang , Dietmar Saupe

Medical patient data is always multimodal. Images, text, age, gender, histopathological data are only few examples for different modalities in this context. Processing and integrating this multimodal data with deep learning based methods is…

Artificial Intelligence · Computer Science 2025-09-11 Christian Gapp , Elias Tappeiner , Martin Welk , Rainer Schubert

With promising results of machine learning based models in computer vision, applications on medical imaging data have been increasing exponentially. However, generalizations to complex real-world clinical data is a persistent problem. Deep…

Computer Vision and Pattern Recognition · Computer Science 2020-07-27 Nooshin Mojab , Vahid Noroozi , Darvin Yi , Manoj Prabhakar Nallabothula , Abdullah Aleem , Phillip S. Yu , Joelle A. Hallak

Recently, iris recognition is regaining prominence in immersive applications such as extended reality as a means of seamless user identification. This application scenario introduces unique challenges compared to traditional iris…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Yuxi Mi , Qiuyang Yuan , Zhizhou Zhong , Xuan Zhao , Jiaogen Zhou , Fubao Zhu , Jihong Guan , Shuigeng Zhou