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Related papers: Enhanced diffusion and chemotaxis at the nanoscale

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Cells frequently employ extracellular vesicles, or exosomes, to signal across long distances and coordinate collective actions. Exosomes diffuse slowly, can be actively degraded, and contain stochastic amounts of molecular cargo. These…

Biological Physics · Physics 2025-10-15 Louis González , Andrew Mugler

Chemotaxis is a directed cell movement in response to external chemical stimuli. In this paper, we propose a simple model for the origin of chemotaxis - namely how a directed movement in response to an external chemical signal may occur…

Analysis of PDEs · Mathematics 2023-06-30 Yishu Gong , Alexander Kiselev

Theoretical analysis, which maps single molecule time trajectories of a molecular motor onto unicyclic Markov processes, allows us to evaluate the heat dissipated from the motor and to elucidate its dependence on the mean velocity and…

Subcellular Processes · Quantitative Biology 2017-04-05 Wonseok Hwang , Changbong Hyeon

In this paper, we derive a new chemotaxis model with degenerate diffusion and density-dependent chemotactic sensitivity, and we provide a more realistic description of cell migration process for its early and late stages. Different from the…

Analysis of PDEs · Mathematics 2023-07-19 Tianyuan Xu , Shanming Ji , Chunhua Jin , Ming Mei , Jingxue Yin

The use of bacteria has been attractive to cancer researchers as drug delivery vehicle because motile bacteria are able to penetrate in tumors. In particular, the combination of therapeutic bacteria and conventional chemotherapy leads to…

Tissues and Organs · Quantitative Biology 2020-01-06 Hiroaki Shirai , Kosuke Tsukada

Enhanced sampling algorithms have emerged as powerful methods to extend the utility of molecular dynamics simulations and allow the sampling of larger portions of the configuration space of complex systems in a given amount of simulation…

Statistical Mechanics · Physics 2022-12-19 Jérôme Hénin , Tony Lelièvre , Michael R. Shirts , Omar Valsson , Lucie Delemotte

We investigate the dynamics of nanoscale droplets in the vicinity of chemical steps which separate parts of a substrate with different wettabilities. Due to long-ranged dispersion forces, nanodroplets positioned on one side of the step…

Soft Condensed Matter · Physics 2009-09-29 A. Moosavi , M. Rauscher , S. Dietrich

Bubble formation in electrochemical system often hinders reaction efficiency by reducing active surface area and obstructing mass transfer, yet the mechanisms governing their nanoscale nucleation dynamics and impact remains unclear. In this…

Soft Condensed Matter · Physics 2025-09-26 Zhenlei Wanga , Yaxi Yua , Mengkai Qin , Hao Jiang , Zhenjiang Guo , Lu Bai , Limin Wang , Xiaochun Zhang , Xiangping Zhang , Yawei Liu

During batch growth on mixtures of two growth-limiting substrates, microbes consume the substrates either sequentially or simultaneously. These growth patterns are manifested in all types of bacteria and yeasts. The ubiquity of these growth…

Cell Behavior · Quantitative Biology 2008-01-09 Jason T. Noel , Atul Narang

Scaling analysis exploiting timescale separation has been one of the most important techniques in the quantitative analysis of nonlinear dynamical systems in mathematical and theoretical biology. In the case of enzyme catalyzed reactions,…

Quantitative Methods · Quantitative Biology 2023-03-21 Justin Eilertsen , Wylie Stroberg , Santiago Schnell

Durotaxis motion is a spectacular phenomenon manifesting itself by the autonomous motion of a nano-object between parts of a substrate with different stiffness. This motion usually takes place along a stiffness gradient from softer to…

Fluid Dynamics · Physics 2023-11-07 Russell Kajouri , Panagiotis E. Theodorakis , Jan Židek , Andrey Milchev

A spatio-temporal evolution of chemicals appearing in a reversible enzyme reaction and modelled by a four component reaction-diffusion system with the reaction terms obtained by the law of mass action is considered. The large time behaviour…

Analysis of PDEs · Mathematics 2016-10-25 Jan Elias

Coarsening of bicontinuous microstructures is observed in a variety of systems, such as nanoporous metals and mixtures that have undergone spinodal decomposition. To better understand the morphological evolution of these structures during…

Soft Condensed Matter · Physics 2020-10-28 W. Beck Andrews , Kate L. M. Elder , Peter W. Voorhees , Katsuyo Thornton

It has long been asserted that proteins like transcription factors may locate their target in DNA sequences at rates that surpass by several orders of magnitude the three-dimensional diffusion limit thank to facilitated diffusion, that is…

Biological Physics · Physics 2010-09-27 Ana-Maria Florescu , Marc Joyeux

The nonlinear diffusion in multicomponent liquids under chemical reactions influence has been studied. The theory is applied to the analysis of mass transfer in a solution of acetone-benzene. It has been shown, that the creation of…

Fluid Dynamics · Physics 2010-05-20 Vjacheslav V. Obukhovsky , Viktoriya V. Nikonova

Diffusion models are important in tissue engineering as they enable an understanding of molecular delivery to cells in tissue constructs. As three-dimensional (3D) tissue constructs become larger, more intricate, and more clinically…

Tissues and Organs · Quantitative Biology 2015-12-22 Richard J. McMurtrey

In this paper we examine boundary effects in a fractional chemotactic equation derived from a kinetic transport model describing cell movement in response to chemical gradients (chemotaxis). Specifically, we analyze reflecting boundary…

Analysis of PDEs · Mathematics 2025-06-05 Gissell Estrada-Rodriguez , Heiko Gimperlein

In this paper, we propose a kinetic model describing the collective motion by chemotaxis of two species in interaction emitting the same chemoattractant. Such model can be seen as a generalisation to several species of the Othmer-Dunbar-Alt…

Analysis of PDEs · Mathematics 2014-04-21 Luís Almeida , Casimir Emako , Nicolas Vauchelet

We revisit the theory of ion transport in parallel-plate channels and also discuss how the wettability of a solid and the mobility of adsorbed surface charges impact the transport of ions. It is shown that depending on the ratio of the…

Soft Condensed Matter · Physics 2021-09-29 Olga I. Vinogradova , Elena F. Silkina , Evgeny S. Asmolov

We study a chemotaxis-consumption mechanism, in which some chemical signal and cells density interact each other. In order to control the concentration of such a population, sources involving gradient nonlinearities, which introduce a…

Analysis of PDEs · Mathematics 2025-01-24 Daniel Acosta Soba , Alessandro Columbu , Giuseppe Viglialoro
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