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Recent works leveraging Graph Neural Networks to approach graph matching tasks have shown promising results. Recent progress in learning discrete distributions poses new opportunities for learning graph matching models. In this work, we…

Machine Learning · Computer Science 2021-09-14 Linfeng Liu , Michael C. Hughes , Soha Hassoun , Li-Ping Liu

Network topology inference is a cornerstone problem in statistical analyses of complex systems. In this context, the fresh look advocated here permeates benefits from convex optimization and graph signal processing, to identify the…

Social and Information Networks · Computer Science 2016-04-12 Santiago Segarra , Antonio G. Marques , Gonzalo Mateos , Alejandro Ribeiro

We address the problem of identifying a graph structure from the observation of signals defined on its nodes. Fundamentally, the unknown graph encodes direct relationships between signal elements, which we aim to recover from observable…

Social and Information Networks · Computer Science 2016-08-11 Santiago Segarra , Antonio G. Marques , Gonzalo Mateos , Alejandro Ribeiro

Graph generative models have broad applications in biology, chemistry and social science. However, modelling and understanding the generative process of graphs is challenging due to the discrete and high-dimensional nature of graphs, as…

Machine Learning · Computer Science 2022-12-06 Han Huang , Leilei Sun , Bowen Du , Yanjie Fu , Weifeng Lv

We consider the following problem closely related to graph isomorphism. In a simplified version, the task is to compute the automorphism group of a given set family (or a hypergraph), that is, the group of all automorphisms of the given…

Discrete Mathematics · Computer Science 2022-06-29 Deniz Ağaoğlu Çağırıcı , Petr Hliněný

Symmetry breaking for graphs and other combinatorial objects is notoriously hard. On the one hand, complete symmetry breaks are exponential in size. On the other hand, current, state-of-the-art, partial symmetry breaks are often considered…

Logic in Computer Science · Computer Science 2026-04-01 Michael Codish , Mikoláš Janota

Graph pattern matching, which aims to discover structural patterns in graphs, is considered one of the most fundamental graph mining problems in many real applications. Despite previous efforts, existing systems face two main challenges.…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-09-30 Tianhui Shi , Mingshu Zhai , Yi Xu , Jidong Zhai

Anomaly detection in dynamic graphs presents a significant challenge due to the temporal evolution of graph structures and attributes. The conventional approaches that tackle this problem typically employ an unsupervised learning framework,…

Machine Learning · Computer Science 2024-08-16 Jie Liu , Xuequn Shang , Xiaolin Han , Kai Zheng , Hongzhi Yin

Motivation: Exploring drug-protein interactions (DPIs) work as a pivotal step in drug discovery. The fast expansion of available biological data enables computational methods effectively assist in experimental methods. Among them, deep…

Machine Learning · Computer Science 2021-02-01 Yifan Wu , Min Gao , Min Zeng , Feiyang Chen , Min Li , Jie Zhang

Identifying brain regions that exhibit altered functional connectivity across cognitive or emotional states is a key problem in neuroscience. Existing methods, such as edge-wise testing, seed-based psychophysiological interaction (PPI)…

Methodology · Statistics 2026-02-12 Shira Yoffe , Ziv Ben-Zion , Guy Gurevitch , Talma Hendler , Malka Gorfine , Ariel Jaffe

Graph topology identification (GTI) is a central challenge in networked systems, where the underlying structure is often hidden, yet nodal data are available. Conventional solutions to address these challenges rely on probabilistic models…

Signal Processing · Electrical Eng. & Systems 2026-02-18 Yongsheng Han , Raj Thilak Rajan , Geert Leus

Stepwise inference protocols, such as scratchpads and chain-of-thought, help language models solve complex problems by decomposing them into a sequence of simpler subproblems. Despite the significant gain in performance achieved via these…

Machine Learning · Computer Science 2024-02-13 Mikail Khona , Maya Okawa , Jan Hula , Rahul Ramesh , Kento Nishi , Robert Dick , Ekdeep Singh Lubana , Hidenori Tanaka

Data imputation is an effective way to handle missing data, which is common in practical applications. In this study, we propose and test a novel data imputation process that achieve two important goals: (1) preserve the row-wise…

Machine Learning · Computer Science 2023-09-13 Katrina Chen , Xiuqin Liang , Zheng Ma , Zhibin Zhang

We devise a novel inference algorithm to effectively solve the cancer progression model reconstruction problem. Our empirical analysis of the accuracy and convergence rate of our algorithm, CAncer PRogression Inference (CAPRI), shows that…

In a reconfiguration problem, we are given two feasible solutions of a combinatorial problem and our goal is to determine whether it is possible to reconfigure one into the other, with the steps dictated by specific reconfiguration rules.…

Data Structures and Algorithms · Computer Science 2025-01-27 Tatsuhiro Suga , Akira Suzuki , Yuma Tamura , Xiao Zhou

Comorbidity, the co-occurrence of multiple medical conditions in a single patient, profoundly impacts disease management and outcomes. Understanding these complex interconnections is crucial, especially in contexts where comorbidities…

Machine Learning · Computer Science 2025-10-13 Xihan Qin , Li Liao

Entropy metrics (for example, permutation entropy) are nonlinear measures of irregularity in time series (one-dimensional data). Some of these entropy metrics can be generalised to data on periodic structures such as a grid or lattice…

Combinatorics · Mathematics 2021-10-22 John Stewart Fabila-Carrasco , Chao Tan , Javier Escudero

Reconstructing transcriptional regulatory networks is an important task in functional genomics. Data obtained from experiments that perturb genes by knockouts or RNA interference contain useful information for addressing this reconstruction…

Machine Learning · Statistics 2015-06-18 Ali Shojaie , Alexandra Jauhiainen , Michael Kallitsis , George Michailidis

This paper presents a new graph isomorphism invariant, called $\mathfrak{w}$-labeling, that can be used to design a polynomial-time algorithm for solving the graph isomorphism problem for various graph classes. For example, all…

Data Structures and Algorithms · Computer Science 2023-01-24 Alpár Jüttner , Péter Madarasi

Predicting how genetic perturbations change cellular state is a core problem for building controllable models of gene regulation. Perturbations targeting the same gene can produce different transcriptional responses depending on their…

Genomics · Quantitative Biology 2026-02-12 Boyang Fu , George Dasoulas , Sameer Gabbita , Xiang Lin , Shanghua Gao , Xiaorui Su , Soumya Ghosh , Marinka Zitnik