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Low-dose computed tomography (LDCT) reduces patient radiation exposure but introduces substantial noise that degrades image quality and hinders diagnostic accuracy. Existing denoising approaches often require many diffusion steps, limiting…

Medical Physics · Physics 2025-10-29 Qiang Li , Mojtaba Safari , Shansong Wang , Huiqiao Xie , Jie Ding , Tonghe Wang , Xiaofeng Yang

Purpose: Cone-beam CT (CBCT) plays an important role in image guided radiation therapy (IGRT). However, the large radiation dose from serial CBCT scans in most IGRT procedures raises a clinical concern, especially for pediatric patients who…

Medical Physics · Physics 2015-05-18 Xun Jia , Yifei Lou , Ruijiang Li , William Y. Song , Steve B. Jiang

Cone beam computed tomography (CBCT) is an emerging medical imaging technique to visualize the internal anatomical structures of patients. During a CBCT scan, several projection images of different angles or views are collectively utilized…

Image and Video Processing · Electrical Eng. & Systems 2024-01-18 Heejun Shin , Taehee Kim , Jongho Lee , Se Young Chun , Seungryung Cho , Dongmyung Shin

Digital breast tomosynthesis (DBT) exams should utilize the lowest possible radiation dose while maintaining sufficiently good image quality for accurate medical diagnosis. In this work, we propose a convolution neural network (CNN) to…

Image and Video Processing · Electrical Eng. & Systems 2022-03-23 Rodrigo de Barros Vimieiro , Chuang Niu , Hongming Shan , Lucas Rodrigues Borges , Ge Wang , Marcelo Andrade da Costa Vieira

Cone Beam Computed Tomography (CBCT) is widely used in medical imaging. However, the limited number and intensity of X-ray projections make reconstruction an ill-posed problem with severe artifacts. NeRF-based methods have achieved great…

Image and Video Processing · Electrical Eng. & Systems 2025-06-25 Zhuowei Xu , Han Li , Dai Sun , Zhicheng Li , Yujia Li , Qingpeng Kong , Zhiwei Cheng , Nassir Navab , S. Kevin Zhou

This study aimed to propose a denoising method for dynamic contrast-enhanced computed tomography (DCE-CT) perfusion studies using a three-dimensional deep image prior (DIP), and to investigate its usefulness in comparison with total…

Medical Physics · Physics 2023-04-04 Kenya Murase

X-ray photon-counting computed tomography (PCCT) for extremity allows multi-energy high-resolution (HR) imaging but its radiation dose can be further improved. Despite the great potential of deep learning techniques, their application in HR…

Cone-beam computed tomography (CBCT) typically requires hundreds of X-ray projections, which raises concerns about radiation exposure. While sparse-view reconstruction reduces the exposure by using fewer projections, it struggles to achieve…

Image and Video Processing · Electrical Eng. & Systems 2024-11-05 Meng-Xun Li , Jin-Gang Yu , Yuan Gao , Cui Huang , Gui-Song Xia

Recently, a number of approaches to low-dose computed tomography (CT) have been developed and deployed in commercialized CT scanners. Tube current reduction is perhaps the most actively explored technology with advanced image reconstruction…

Medical Physics · Physics 2018-09-05 Hoyeon Lee , Jongha Lee , Hyeongseok Kim , Byungchul Cho , Seungryong Cho

To reduce radiation exposure and improve the diagnostic efficacy of low-dose computed tomography (LDCT), numerous deep learning-based denoising methods have been developed to mitigate noise and artifacts. However, most of these approaches…

Image and Video Processing · Electrical Eng. & Systems 2025-08-12 Runze Wang , Zeli Chen , Zhiyun Song , Wei Fang , Jiajin Zhang , Danyang Tu , Yuxing Tang , Minfeng Xu , Xianghua Ye , Le Lu , Dakai Jin

Recently, deep learning (DL)-based methods for the generation of synthetic computed tomography (sCT) have received significant research attention as an alternative to classical ones. We present here a systematic review of these methods by…

Medical Physics · Physics 2021-08-30 Maria Francesca Spadea , Matteo Maspero , Paolo Zaffino , Joao Seco

Computed tomography (CT) is widely used in screening, diagnosis, and image-guided therapy for both clinical and research purposes. Since CT involves ionizing radiation, an overarching thrust of related technical research is development of…

Image and Video Processing · Electrical Eng. & Systems 2019-06-25 Chenyu You , Guang Li , Yi Zhang , Xiaoliu Zhang , Hongming Shan , Shenghong Ju , Zhen Zhao , Zhuiyang Zhang , Wenxiang Cong , Michael W. Vannier , Punam K. Saha , Ge Wang

Imaging of teeth is very important to doctors in the diagnosis and treatment of dental diseases. The main imaging modality currently used is Cone-Beam Computed Tomography (CBCT), which however suffers from ionizing radiation causing…

Medical Physics · Physics 2023-04-13 Yuting Shen , Yiyun Wang , Chengxiao Liu , Niansong Ye , Feng Gao , Lunguo Xia , Bing Fang , Fei Gao

The restoration of images affected by blur and noise has been widely studied and has broad potential for applications including in medical imaging modalities like computed tomography (CT). Although the blur and noise in CT images can be…

Medical Physics · Physics 2024-07-23 Yijie Yuan , Grace J. Gang , J. Webster Stayman

Diagnostic stroke imaging with C-arm cone-beam computed tomography (CBCT) enables reduction of time-to-therapy for endovascular procedures. However, the prolonged acquisition time compared to helical CT increases the likelihood of rigid…

Image and Video Processing · Electrical Eng. & Systems 2019-12-02 Alexander Preuhs , Michael Manhart , Philipp Roser , Bernhard Stimpel , Christopher Syben , Marios Psychogios , Markus Kowarschik , Andreas Maier

Low-dose computed tomography (LDCT) is the standard modality for lung cancer screening, known for its low radiation dose but high noise levels. While existing literature focuses on denoising LDCT images, comparative research on simulating…

Image and Video Processing · Electrical Eng. & Systems 2026-05-13 Jiaying Liu , Anna Corti , Valentina D. A. Corino , Luca Mainardi

Cone beam computed tomography (CBCT) images can be used for dose calculation in adaptive radiation therapy (ART). The main challenges are the large artefacts and inaccurate Hounsfield unit (HU) values. Currently, deformed planning CT images…

Medical Physics · Physics 2019-09-04 Xiao Liang , Liyuan Chen , Dan Nguyen , Zhiguo Zhou , Xuejun Gu , Ming Yang , Jing Wang , Steve Jiang

Low-dose CT (LDCT) reduces radiation exposure but introduces protocol-dependent noise and artifacts that vary across institutions. While federated learning enables collaborative training without centralizing patient data, existing methods…

Image and Video Processing · Electrical Eng. & Systems 2026-03-17 Anas Zafar , Muhammad Waqas , Amgad Muneer , Rukhmini Bandyopadhyay , Jia Wu

Cone Beam Computed Tomography (CBCT) finds diverse applications in medicine. Ensuring high image quality in CBCT scans is essential for accurate diagnosis and treatment delivery. Yet, the susceptibility of CBCT images to noise and artifacts…

Computer Vision and Pattern Recognition · Computer Science 2024-09-30 Yunkui Pang , Yilin Liu , Xu Chen , Pew-Thian Yap , Jun Lian

Cone-beam computed tomography (CBCT) is an imaging modality widely used in head and neck diagnostics due to its accessibility and lower radiation dose. However, its relatively long acquisition times make it susceptible to patient motion,…