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The past decade marked a drastic increase in the usage of electronic cigarettes (e-cigs). The adverse health impact of secondhand exposure due to exhaled e-cig particles has raised significant concerns, demanding further research on the…

Applied Physics · Physics 2022-02-18 Ege Cetintas , Yi Luo , Charlene Nguyen , Yuening Guo , Liqiao Li , Yifang Zhu , Aydogan Ozcan

Exposure to bio-aerosols such as mold spores and pollen can lead to adverse health effects. There is a need for a portable and cost-effective device for long-term monitoring and quantification of various bio-aerosols. To address this need,…

Applied Physics · Physics 2022-11-23 Yi Luo , Yijie Zhang , Tairan Liu , Alan Yu , Yichen Wu , Aydogan Ozcan

We demonstrate the use of holographic video microscopy to detect individual subvisible particles dispersed in biopharmaceutical formulations and to differentiate them based on material characteristics measured from their holograms. The…

We introduce the holographic air-quality monitor (HAM) system, uniquely tailored for monitoring large particulate matter (PM) over 10 um in diameter, i.e., particles critical for disease transmission and public health but overlooked by most…

Instrumentation and Detectors · Physics 2024-09-09 Nicholas Bravo-Frank , Lei Feng , Jiarong Hong

Some microalgae store large amounts of neutral lipids inside lipid droplets. Since these lipids can be used to produce biodiesel in a sustainable way, research is developing on fast non-destructive methods to quantify and monitor the amount…

Biological Physics · Physics 2024-03-14 Catherine Yourassowsky , Renaud Theunissen , JÉrÔme Dohet-Eraly , Frank Dubois

To evaluate shear viscosity of ethylene glycol oligomers (EGO)/water binary mixture by means of coarse-grained molecular dynamics (CG-MD) simulations, we proposed the self-diffusion-coefficient-based parameterization of non-bonded…

Mathematical Physics · Physics 2012-08-07 Tamio Yamazaki

Efficient monitoring of airborne particulate matter (PM), especially particles with aerodynamic diameter less than 2.5 um (PM2.5), is crucial for improving public health. Reliable information on the concentration, size distribution and…

Applied Physics · Physics 2020-01-08 Abhinav Sharma , Shangran Xie , Richard Zeltner , Philip St. J. Russell

Differential dynamic microscopy (DDM) typically relies on movies containing hundreds or thousands of frames to accurately quantify motion in soft matter systems. Using movies much shorter in duration produces noisier and less accurate…

Soft Condensed Matter · Physics 2024-11-05 Gildardo Martinez , Justin Siu , Steven Dang , Dylan Gage , Emma Kao , Juan Carlos Avila , Ruilin You , Ryan McGorty

Confocal microscopy of fluorescent labeled particles has been used to study the dynamical and structural properties of colloidal and granular matter in real space. Localization algorithms allow for a fully automatized determination of the…

Soft Condensed Matter · Physics 2011-12-08 Marcel Roth , Michael Franzmann , Maria D'Acunzi , Max Kreiter , Günter K. Auernhammer

The nonlinear features of the relationships between concentrations of aerosol and volatile organic compounds (VOC) and oxides of nitrogen (NOx) in urban environments are derived directly from data of long-term routine measurements of NOx,…

Atmospheric and Oceanic Physics · Physics 2020-11-04 Igor B. Konovalov

Microscopic analysis of micro particles in situ in diverse water environments is necessary for monitoring water quality and localizing contamination sources. Conventional sensors such as optical microscopes and fluorometers often require…

Robotics · Computer Science 2019-11-26 Kevin Mallery , Dario Canelon , Jiarong Hong , Nikolaos Papanikolopoulos

We developed a digital inline holography (DIH) system integrated with deep learning algorithms for real-time detection of particulate matter (PM) and bacterial contamination in peritoneal dialysis (PD) fluids. The system comprises a…

Optics · Physics 2024-11-05 Nicholas Bravo-Frank , Nicolas Mesyngier , Lei Feng , Jiarong Hong

Aerosol particles play an important role in the climate system by absorbing and scattering radiation and influencing cloud properties. They are also one of the biggest sources of uncertainty for climate modeling. Many climate models do not…

Machine Learning · Computer Science 2022-07-26 Paula Harder , Duncan Watson-Parris , Philip Stier , Dominik Strassel , Nicolas R. Gauger , Janis Keuper

Volatile Organic Compounds (VOCs) are organic molecules that have low boiling points and therefore easily evaporate into the air. They pose significant risks to human health, making their accurate detection the crux of efforts to monitor…

EMG-based gesture recognition shows promise for human-machine interaction. Systems are often afflicted by signal and electrode variability which degrades performance over time. We present an end-to-end system combating this variability…

Aerosol particles play an important role in the climate system by absorbing and scattering radiation and influencing cloud properties. They are also one of the biggest sources of uncertainty for climate modeling. Many climate models do not…

Machine Learning · Computer Science 2021-09-30 Paula Harder , Duncan Watson-Parris , Dominik Strassel , Nicolas Gauger , Philip Stier , Janis Keuper

The transport of bio-particles in viscous flows exhibits a rich variety of dynamical behaviour, such as morphological transitions, complex orientation dynamics or deformations. Characterising such complex behaviour under well controlled…

Despite its potential for label-free particle diagnostics, holographic microscopy is limited by specialized processing methods that struggle to generalize across diverse settings. We introduce a deep learning architecture leveraging human…

Optics · Physics 2024-11-26 Shyam Kumar , Jiarong Hong

Aggregation-based assays, using micro- and nano-particles have been widely accepted as an efficient and cost-effective bio-sensing tool, particularly in microbiology, where particle clustering events are used as a metric to infer the…

Instrumentation and Detectors · Physics 2018-12-31 Yichen Wu , Aniruddha Ray , Qingshan Wei , Alborz Feizi , Xin Tong , Eva Chen , Yi Luo , Aydogan Ozcan

Particle size measurement based on digital holography with conventional algorithms are usually time-consuming and susceptible to noises associated with hologram quality and particle complexity, limiting its usage in a broad range of…

Applied Physics · Physics 2020-01-01 Siyao Shao , Kevin Mallery , Jiarong Hong
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