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The interpretability of deep neural networks has become a subject of great interest within the medical and healthcare domain. This attention stems from concerns regarding transparency, legal and ethical considerations, and the medical…

Image and Video Processing · Electrical Eng. & Systems 2023-11-20 Mahbub Ul Alam , Jaakko Hollmén , Jón Rúnar Baldvinsson , Rahim Rahmani

We propose a novel approach that integrates machine learning into compartmental disease modeling to predict the progression of COVID-19. Our model is explainable by design as it explicitly shows how different compartments evolve and it uses…

Since the onset of the COVID-19 pandemic in 2020, millions of people have succumbed to this deadly virus. Many attempts have been made to devise an automated method of testing that could detect the virus. Various researchers around the…

Image and Video Processing · Electrical Eng. & Systems 2021-11-11 Samyak Prajapati , Japman Singh Monga , Shaanya Singh , Amrit Raj , Yuvraj Singh Champawat , Chandra Prakash

Lung diseases such as COVID-19, tuberculosis (TB), and pneumonia continue to be serious global health concerns that affect millions of people worldwide. In medical practice, chest X-ray examinations have emerged as the norm for diagnosing…

Image and Video Processing · Electrical Eng. & Systems 2023-10-11 Aditya Kulkarni , Guruprasad Parasnis , Harish Balasubramanian , Vansh Jain , Anmol Chokshi , Reena Sonkusare

This paper applies eXplainable Artificial Intelligence (XAI) methods to investigate the socioeconomic disparities in COVID patient mortality. An Extreme Gradient Boosting (XGBoost) prediction model is built based on a de-identified Austin…

Machine Learning · Computer Science 2023-02-24 Li Shi , Redoan Rahman , Esther Melamed , Jacek Gwizdka , Justin F. Rousseau , Ying Ding

The development of AI-based methods to analyze radiology reports could lead to significant advances in medical diagnosis, from improving diagnostic accuracy to enhancing efficiency and reducing workload. However, the lack of…

Computation and Language · Computer Science 2025-08-14 Yuyan Ge , Kwan Ho Ryan Chan , Pablo Messina , René Vidal

Attribution methods explain neural network predictions by identifying influential input features, but their evaluation suffers from threshold selection bias that can reverse method rankings and undermine conclusions. Current protocols…

Machine Learning · Computer Science 2025-09-04 Serra Aksoy

Explainability is a key requirement for computer-aided diagnosis systems in clinical decision-making. Multiple instance learning with attention pooling provides instance-level explainability, however for many clinical applications a deeper,…

Image and Video Processing · Electrical Eng. & Systems 2023-03-16 Ario Sadafi , Oleksandra Adonkina , Ashkan Khakzar , Peter Lienemann , Rudolf Matthias Hehr , Daniel Rueckert , Nassir Navab , Carsten Marr

A major prerequisite for the application of machine learning models in clinical decision making is trust and interpretability. Current explainability studies in the neuroimaging community have mostly focused on explaining individual…

Computer Vision and Pattern Recognition · Computer Science 2022-03-25 Fabian Eitel , Anna Melkonyan , Kerstin Ritter

Graph Neural Networks (GNNs) have gained considerable traction for their capability to effectively process topological data, yet their interpretability remains a critical concern. Current interpretation methods are dominated by post-hoc…

Machine Learning · Computer Science 2024-02-08 Jiahua Rao , Jiancong Xie , Hanjing Lin , Shuangjia Zheng , Zhen Wang , Yuedong Yang

Machine learning, particularly convolutional neural networks (CNNs), has shown promise in medical image analysis, especially for thoracic disease detection using chest X-ray images. In this study, we evaluate various CNN architectures,…

Computer Vision and Pattern Recognition · Computer Science 2025-02-18 Tejas Mirthipati

The success of machine learning methods for computer vision tasks has driven a surge in computer assisted prediction for medicine and biology. Based on a data-driven relationship between input image and pathological classification, these…

Computer Vision and Pattern Recognition · Computer Science 2020-10-02 Dimitrios Lenis , David Major , Maria Wimmer , Astrid Berg , Gert Sluiter , Katja Bühler

Current standard protocols used in the clinic for diagnosing COVID-19 include molecular or antigen tests, generally complemented by a plain chest X-Ray. The combined analysis aims to reduce the significant number of false negatives of these…

Image and Video Processing · Electrical Eng. & Systems 2020-12-01 Julian D. Arias-Londoño , Jorge A. Gomez-Garcia , Laureano Moro-Velazquez , Juan I. Godino-Llorente

Graph neural networks (GNNs) are increasingly used to model biological systems, yet the reliability of post-hoc explanation methods for recovering meaningful molecular mechanisms remains unclear. Here, we systematically evaluate four widely…

Molecular Networks · Quantitative Biology 2026-05-22 Kyle Higgins , Ivan Laponogov , Dennis Veselkov , Kirill Veselkov

Pretrained transformers achieve the state of the art across tasks in natural language processing, motivating researchers to investigate their inner mechanisms. One common direction is to understand what features are important for…

Computation and Language · Computer Science 2021-08-06 Zhiying Jiang , Raphael Tang , Ji Xin , Jimmy Lin

Interpretability in Graph Convolutional Networks (GCNs) has been explored to some extent in computer vision in general, yet, in the medical domain, it requires further examination. Moreover, most of the interpretability approaches for GCNs,…

Computer Vision and Pattern Recognition · Computer Science 2021-03-30 Anees Kazi , Soroush Farghadani , Nassir Navab

Chest X-rays (X-ray images) have been proven to be effective for the diagnosis of chest diseases, including Pneumonia, Lung Opacity, and COVID-19. However, relying on traditional medical methods for diagnosis from X-ray images is prone to…

Image and Video Processing · Electrical Eng. & Systems 2025-10-01 Omar Hesham Khater , Abdullahi Sani Shuaib , Sami Ul Haq , Abdul Jabbar Siddiqui

Importance: An artificial intelligence (AI)-based model to predict COVID-19 likelihood from chest x-ray (CXR) findings can serve as an important adjunct to accelerate immediate clinical decision making and improve clinical decision making.…

Chest imaging plays an essential role in diagnosing and predicting patients with COVID-19 with evidence of worsening respiratory status. Many deep learning-based approaches for pneumonia recognition have been developed to enable…

Image and Video Processing · Electrical Eng. & Systems 2024-01-17 Shengchao Chen , Sufen Ren , Guanjun Wang , Mengxing Huang , Chenyang Xue

Attribution maps are one of the most established tools to explain the functioning of computer vision models. They assign importance scores to input features, indicating how relevant each feature is for the prediction of a deep neural…

Computer Vision and Pattern Recognition · Computer Science 2024-12-10 Robin Hesse , Simone Schaub-Meyer , Stefan Roth