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Related papers: Clustering Schemes on the Torus with Application t…

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RNA structure determination is essential for understanding its biological functions. However, the reconstruction process often faces challenges, such as atomic clashes, which can lead to inaccurate models. To address these challenges, we…

Biomolecules · Quantitative Biology 2026-03-04 Menghao Wu , Zhigang Yao

There are several cutting edge applications needing PCA methods for data on tori and we propose a novel torus-PCA method with important properties that can be generally applied. There are two existing general methods: tangent space PCA and…

Methodology · Statistics 2015-11-17 Benjamin Eltzner , Stephan Huckemann , Kanti V. Mardia

We study clustering on graphs with multiple edge types. Our main motivation is that similarities between objects can be measured in many different metrics. For instance similarity between two papers can be based on common authors, where…

Social and Information Networks · Computer Science 2011-09-09 Matthew Rocklin , Ali Pinar

Unsupervised clustering algorithms for vectors has been widely used in the area of machine learning. Many applications, including the biological data we studied in this paper, contain some boundary datapoints which show combination…

Machine Learning · Computer Science 2022-05-23 Yingcong Li , Chandra Sekhar Mukherjee , Jiapeng Zhang

The paper concerns clustering with respect to the shape and size of 2D contours that are boundaries of cross-sections of 3D objects of revolution. We propose a number of similarity measures based on combined disparate Procrustes analysis…

Computer Vision and Pattern Recognition · Computer Science 2021-11-15 Agnieszka Kaliszewska , Monika Syga

Spectral clustering is a fundamental technique in the field of data mining and information processing. Most existing spectral clustering algorithms integrate dimensionality reduction into the clustering process assisted by manifold learning…

Machine Learning · Computer Science 2014-11-25 Xiaojun Chang , Feiping Nie , Zhigang Ma , Yi Yang , Xiaofang Zhou

We consider a generalized version of the correlation clustering problem, defined as follows. Given a complete graph $G$ whose edges are labeled with $+$ or $-$, we wish to partition the graph into clusters while trying to avoid errors: $+$…

Data Structures and Algorithms · Computer Science 2016-05-25 Gregory J. Puleo , Olgica Milenkovic

There is a growing interest in characterizing circular data found in biological systems. Such data are wide ranging and varied, from signal phase in neural recordings to nucleotide sequences in round genomes. Traditional clustering…

Machine Learning · Computer Science 2023-09-19 Xiaoxiao Sun , Paul Sajda

Clustering of proteins is of interest in cancer cell biology. This article proposes a hierarchical Bayesian model for protein (variable) clustering hinging on correlation structure. Starting from a multivariate normal likelihood, we enforce…

Computation · Statistics 2022-02-09 Riddhi Pratim Ghosh , Arnab Kumar Maity , Mohsen Pourahmadi , Bani K. Mallick

Cancer is a number of related yet highly heterogeneous diseases. Correct identification of cancer subtypes is critical for clinical decisions. The advance in sequencing technologies has made it possible to study cancer based on abundant…

Applications · Statistics 2018-11-27 Xiaochun Chen , Honggang Wang , Donghui Yan

This paper presents a clustering approach that allows for rigorous statistical error control similar to a statistical test. We develop estimators for both the unknown number of clusters and the clusters themselves. The estimators depend on…

Statistics Theory · Mathematics 2017-07-13 Michael Vogt , Matthias Schmid

Mixed data comprises both numeric and categorical features, and mixed datasets occur frequently in many domains, such as health, finance, and marketing. Clustering is often applied to mixed datasets to find structures and to group similar…

Machine Learning · Computer Science 2019-03-20 Amir Ahmad , Shehroz S. Khan

Unsupervised clustering of curves according to their shapes is an important problem with broad scientific applications. The existing model-based clustering techniques either rely on simple probability models (e.g., Gaussian) that are not…

Machine Learning · Statistics 2015-04-03 Zhengwu Zhang , Debdeep Pati , Anuj Srivastava

Cluster analysis has proved to be an invaluable tool for the exploratory and unsupervised analysis of high dimensional datasets. Among methods for clustering, hierarchical approaches have enjoyed substantial popularity in genomics and other…

Methodology · Statistics 2014-11-20 Patrick K. Kimes , Yufeng Liu , D. Neil Hayes , J. S. Marron

RNA folding prediction remains challenging, but can be also studied using a topological mathematical approach. In the present paper, the mathematical method to compute the topological classification of RNA structures and based on matrix…

Biomolecules · Quantitative Biology 2025-08-11 Nicolò Cangiotti , Stefano Grasso

Time series data, spanning applications ranging from climatology to finance to healthcare, presents significant challenges in data mining due to its size and complexity. One open issue lies in time series clustering, which is crucial for…

Machine Learning · Computer Science 2023-07-07 Jorge Marco-Blanco , Rubén Cuevas

In cancer research, clustering techniques are widely used for exploratory analyses and dimensionality reduction, playing a critical role in the identification of novel cancer subtypes, often with direct implications for patient management.…

Clustering of molecules on biological membranes is a widely observed phenomenon. In some cases, such as the clustering of Ras proteins on the membranes of mammalian cells, proper cell signaling is critically dependent on the maintenance of…

Molecular Networks · Quantitative Biology 2019-08-28 Martijn Wehrens , Pieter Rein ten Wolde , Andrew Mugler

Generative approaches to clustering provide information on geometric properties of clusters, whereas discriminative approaches provide boundaries between clusters. Ideas from both approaches are incorporated to present a fully unsupervised,…

Machine Learning · Statistics 2026-04-28 Mackenzie R. Neal , Paul D. McNicholas , Arthur White

In many applications of shape analysis, lengths between some landmarks are constrained. For instance, biomolecules often have some bond lengths and some bond angles constrained, and variation occurs only along unconstrained bonds and…

Methodology · Statistics 2025-02-25 Kanti V. Mardia , Benjamin Eltzner , Stephan F. Huckemann
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