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Computer-aided early diagnosis of Alzheimer's disease (AD) and its prodromal form mild cognitive impairment (MCI) based on structure Magnetic Resonance Imaging (sMRI) has provided a cost-effective and objective way for early prevention and…

Image and Video Processing · Electrical Eng. & Systems 2021-11-16 Xin Zhang , Liangxiu Han , Wenyong Zhu , Liang Sun , Daoqiang Zhang

We introduce a wide and deep neural network for prediction of progression from patients with mild cognitive impairment to Alzheimer's disease. Information from anatomical shape and tabular clinical data (demographics, biomarkers) are fused…

Machine Learning · Computer Science 2020-04-01 Sebastian Pölsterl , Ignacio Sarasua , Benjamín Gutiérrez-Becker , Christian Wachinger

Deep learning (DL) has been used in the automatic diagnosis of Mild Cognitive Impairment (MCI) and Alzheimer's Disease (AD) with brain imaging data. However, previous methods have not fully exploited the relation between brain image and…

Computer Vision and Pattern Recognition · Computer Science 2023-10-24 Luoyao Kang , Haifan Gong , Xiang Wan , Haofeng Li

State-of-the-art deep learning models are often trained with a large amount of costly labeled training data. However, requiring exhaustive manual annotations may degrade the model's generalizability in the limited-label regime.…

Computer Vision and Pattern Recognition · Computer Science 2022-08-25 Yanbei Chen , Massimiliano Mancini , Xiatian Zhu , Zeynep Akata

Alzheimer's disease (AD) is an irreversible neurodegenerative disorder that progressively destroys memory and other cognitive domains of the brain. While effective therapeutic management of AD is still in development, it seems reasonable to…

Image and Video Processing · Electrical Eng. & Systems 2020-11-10 Oleg Michailovich , Rinat Mukhometzianov

Existing studies on disease diagnostic models focus either on diagnostic model learning for performance improvement or on the visual explanation of a trained diagnostic model. We propose a novel learn-explain-reinforce (LEAR) framework that…

Computer Vision and Pattern Recognition · Computer Science 2021-08-24 Kwanseok Oh , Jee Seok Yoon , Heung-Il Suk

In this tutorial, we explore Variational Autoencoders (VAEs), an essential framework for unsupervised learning, particularly suited for high-dimensional datasets such as neuroimaging. By integrating deep learning with Bayesian inference,…

Image and Video Processing · Electrical Eng. & Systems 2025-01-15 C. Vázquez-García , F. J. Martínez-Murcia , F. Segovia Román , Juan M. Górriz Sáez

Attribution methods are an easy to use tool for investigating and validating machine learning models. Multiple methods have been suggested in the literature and it is not yet clear which method is most suitable for a given task. In this…

Image and Video Processing · Electrical Eng. & Systems 2019-09-20 Fabian Eitel , Kerstin Ritter

Deep learning has demonstrated success in many applications; however, their use in healthcare has been limited due to the lack of transparency into how they generate predictions. Algorithms such as Recurrent Neural Networks (RNNs) when…

Machine Learning · Computer Science 2021-01-14 Long V. Ho , Melissa D. Aczon , David Ledbetter , Randall Wetzel

State-of-the-art, high capacity deep neural networks not only require large amounts of labelled training data, they are also highly susceptible to label errors in this data, typically resulting in large efforts and costs and therefore…

Machine Learning · Computer Science 2020-07-20 Christian Haase-Schütz , Rainer Stal , Heinz Hertlein , Bernhard Sick

In visual object classification, humans often justify their choices by comparing objects to prototypical examples within that class. We may therefore increase the interpretability of deep learning models by imbuing them with a similar style…

Computer Vision and Pattern Recognition · Computer Science 2023-10-26 Ayodeji Ijishakin , Ahmed Abdulaal , Adamos Hadjivasiliou , Sophie Martin , James Cole

In the field of medical imaging, the advent of deep learning, especially the application of convolutional neural networks (CNNs) has revolutionized the analysis and interpretation of medical images. Nevertheless, deep learning methods…

Computer Vision and Pattern Recognition · Computer Science 2025-04-28 Xin Li , Wenhui Zhu , Peijie Qiu , Oana M. Dumitrascu , Amal Youssef , Yalin Wang

Semi-supervised learning has made significant strides in the medical domain since it alleviates the heavy burden of collecting abundant pixel-wise annotated data for semantic segmentation tasks. Existing semi-supervised approaches enhance…

Computer Vision and Pattern Recognition · Computer Science 2021-12-03 Xu Zheng , Chong Fu , Haoyu Xie , Jialei Chen , Xingwei Wang , Chiu-Wing Sham

Alzheimer's disease (AD) is the most common long-term illness in elderly people. In recent years, deep learning has become popular in the area of medical imaging and has had a lot of success there. It has become the most effective way to…

Computer Vision and Pattern Recognition · Computer Science 2023-10-16 Mahin Khan Mahadi , Abdullah Abdullah , Jamal Uddin , Asif Newaz

Multi-modal learning integrating medical images and tabular data has significantly advanced clinical decision-making in recent years. Self-Supervised Learning (SSL) has emerged as a powerful paradigm for pretraining these models on…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Yibing Fu , Yunpeng Zhao , Zhitao Zeng , Cheng Chen , Yueming Jin

Despite the impressive advances achieved using deep learning for functional brain activity analysis, the heterogeneity of functional patterns and the scarcity of imaging data still pose challenges in tasks such as identifying neurological…

Image and Video Processing · Electrical Eng. & Systems 2025-05-30 Wenhui Cui , Haleh Akrami , Anand A. Joshi , Richard M. Leahy

Deep learning has achieved impressive performance across various medical imaging tasks. However, its inherent bias against specific groups hinders its clinical applicability in equitable healthcare systems. A recently discovered phenomenon,…

Computer Vision and Pattern Recognition · Computer Science 2024-11-01 Kaouther Mouheb , Marawan Elbatel , Stefan Klein , Esther E. Bron

Learning discriminative representations for unseen person images is critical for person Re-Identification (ReID). Most of current approaches learn deep representations in classification tasks, which essentially minimize the empirical…

Computer Vision and Pattern Recognition · Computer Science 2019-09-05 Hantao Yao , Shiliang Zhang , Yongdong Zhang , Jintao Li , Qi Tian

Alzheimer's disease (AD) confirmation often relies on positron emission tomography (PET) or cerebrospinal fluid (CSF) analysis, which are costly and invasive. Consequently, structural MRI biomarkers such as cortical thickness (CT) are…

Computer Vision and Pattern Recognition · Computer Science 2026-04-17 Geonwoo Baek , David H. Salat , Ikbeom Jang