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In neurosciences, the brain processes information via the firing patterns of connected neurons operating across a spectrum of frequencies. To better understand the effects of these frequencies in the neuron dynamics, we have simulated a…
The resistive or non-resistive nature of the extracellular space in the brain is still debated, and is an important issue for correctly modeling extracellular potentials. Here, we first show theoretically that if the medium is resistive,…
Neural synchronization is believed to be critical for many brain functions. It frequently exhibits temporal variability, but it is not known if this variability has a specific temporal patterning. This study explores these…
The brain may be thought of as a many-body architecture with a spatio-temporal dynamics described by neuronal structures. The oscillatory nature of brain activity allows these structures (nodes) to be described as a set of coupled…
Background: Direct electrical stimulation of the brain through intracranial electrodes is currently used to probe the epileptic brain as part of pre-surgical evaluation, and it is also being considered for therapeutic treatments through…
Mobility is severely impacted in patients with Parkinson's disease (PD), especially when they experience involuntary stopping from the freezing of gait (FOG). Understanding the neurophysiological difference between "voluntary stopping" and…
With the rapid development of wearable device technologies, accelerometers can record minute-by-minute physical activity for consecutive days, which provides important insight into a dynamic association between the intensity of physical…
The influence of fatiguing stimuli applied to the quadriceps femoris on the tremor of the index finger on sixteen healthy subjects has been investigated, by measuring the acceleration and the electromyography activity of the extensor…
Biological oscillators coordinate individual cellular components so that they function coherently and collectively. They are typically composed of multiple feedback loops, and period mismatch is unavoidable in biological implementations. We…
Slow oscillations are electrical potential oscillations with a spectral peak frequency of $\sim$0.8 Hz, and hallmark the electroencephalogram during slow-wave sleep. Recent studies have indicated a causal contribution of slow oscillations…
Interpreting the environmental, behavioural and psychological data from in-home sensory observations and measurements can provide valuable insights into the health and well-being of individuals. Presents of neuropsychiatric and…
Autism Spectrum Disorder (ASD) is a neurodevelopmental condition associated with difficulties with social interactions, communication, and restricted or repetitive behaviors. To characterize ASD, investigators often use functional…
The neuromagnetic activity (magnetoencephalogram, MEG) from healthy human brain and from an epileptic patient against chromatic flickering stimuli has been earlier analyzed on the basis of a memory functions formalism (MFF). Information…
Alterations in functional brain connectivity characterize neurodegenerative disorders such as Alzheimer's disease (AD) and frontotemporal dementia (FTD). As a non-invasive and cost-effective technique, electroencephalography (EEG) is…
Time irreversibility (temporal asymmetry) is one of fundamental properties that characterize the nonlinearity of complex dynamical processes, and our brain is a typical complex dynamical system manifested with nonlinearity. Two…
Recent analyses combining advanced theoretical techniques and high-quality data from thousands of simultaneously recorded neurons provide strong support for the hypothesis that neural dynamics operate near the edge of instability across…
Electroencephalography (EEG) is a vital tool to measure and record brain activity in neuroscience and clinical applications, yet its potential is constrained by signal heterogeneity, low signal-to-noise ratios, and limited labeled datasets.…
We study the two-scale asymptotics for a charged beam under the action of a rapidly oscillating external electric field. After proving the convergence to the correct asymptotic state, we develop a numerical method for solving the limit…
The prospects of assessing neural complexity (NC) by $q$-statistics of the systemic organization of different types and levels of brain activity were studied. In 70 adult subjects, NC was assessed via the parameter $q$ of $q$-statistics,…
Fatigue is a broad, multifactorial concept that includes the subjective perception of reduced physical and mental energy levels. It is also one of the key factors that strongly affect patients' health-related quality of life. To date, most…