Related papers: High-Sensitivity Iodine Imaging by Combining Spect…
Spectral computed tomography based on a photon-counting detector (PCD) attracts more and more attentions since it has the capability to provide more accurate identification and quantitative analysis for biomedical materials. The limited…
Dual-energy computed tomography (DECT) has been widely used to obtain quantitative elemental composition of imaged subjects for personalized and precise medical diagnosis. Compared with existing high-end DECT leveraging advanced X-ray…
Hybrid spectral CT integrates energy integrating detectors (EID) and photon counting detectors (PCD) into a single system, combining the large field-of-view advantage of EID with the high energy and spatial resolution of PCD. This…
In this work, we perform direct material reconstruction from spectral CT data using a model based iterative reconstruction (MBIR) approach. Material concentrations are measured in volume fractions, whose total is constrained by a maximum of…
Dual-energy computed tomography (DECT) has been widely used to obtain quantitative elemental composition of imaged subjects for personalized and precise medical diagnosis. Compared with DECT leveraging advanced X-ray source and/or detector…
Purpose: Photon-counting computed tomography (PCCT) shows promise for medical imaging in regards to material separation and imaging of multiple contrast agents. However, many PCCT setups are under development and are not optimized for…
Spectral and grating-based differential phase-contrast X-ray imaging are two emerging technologies that offer additional information compared with conventional attenuation-based X-ray imaging. In the case of spectral imaging,…
Multispectral computed tomography (CT) enables advanced material characterization by acquiring energy-resolved projection data. However, since the incoming X-ray flux is be distributed across multiple narrow energy bins, the photon count…
In this work, we introduce a new deep learning approach based on diffusion posterior sampling (DPS) to perform material decomposition from spectral CT measurements. This approach combines sophisticated prior knowledge from unsupervised…
Purpose: Deformable image registration (DIR) is critical in adaptive radiation therapy (ART) to account for anatomical changes. Conventional intensity-based DIR methods often fail when image intensities differ. This study evaluates a hybrid…
Optical Coherence Tomography (OCT) is an emerging technique in the field of biomedical imaging, with applications in ophthalmology, dermatology, coronary imaging etc. OCT images usually suffer from a granular pattern, called speckle noise,…
Spectral computed tomography (CT) has attracted much attention in radiation dose reduction, metal artifacts removal, tissue quantification and material discrimination. The x-ray energy spectrum is divided into several bins, each…
Background: Dual-energy CT (DECT) and material decomposition play vital roles in quantitative medical imaging. However, the decomposition process may suffer from significant noise amplification, leading to severely degraded image…
Purpose: Spectral imaging is a method in medical x-ray imaging to extract information about the object constituents by the material-specific energy dependence of x-ray attenuation. The authors have investigated a photon-counting spectral…
Purpose: Fast kV-switching (FKS) and dual-layer flat-panel detector (DL-FPD) technologies have been actively studied as promising dual-energy solutions for FPD-based cone-beam computed tomography (CBCT). However, CBCT spectral imaging is…
Dual spectral computed tomography (DSCT) can achieve energy- and material-selective images, and has a superior distinguishability of some materials than conventional single spectral computed tomography (SSCT). However, the decomposition…
The intensity levels allowed by safety standards (ANSI or ICNIRP) limit the amount of light that can be used in a clinical setting to image highly scattering or absorptive tissues with Optical Coherence Tomography (OCT). To achieve…
Background: Daily or weekly cone-beam computed tomography (CBCT) scans are commonly used for accurate patient positioning during the image-guided radiotherapy (IGRT) process, making it an ideal option for adaptive radiotherapy (ART)…
Dual-energy computed tomography (DECT) has been widely used in many applications that need material decomposition. Image-domain methods directly decompose material images from high- and low-energy attenuation images, and thus, are…
Photon counting CT (PCCT) has been a research focus in the last two decades. Recent studies and advancements have demonstrated that systems using semiconductor-based photon counting detectors (PCDs) have the potential to provide better…