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Related papers: Toward Building Science Discovery Machines

200 papers

The current structure-centric paradigm in artificial intelligence (AI)-driven materials discovery, despite delivering thousands of candidate structures, is stalling at a critical barrier: the synthesizability gap. We argue that closing this…

Materials Science · Physics 2026-05-04 Guillaume Lambard

Despite the success of neural networks at solving concrete physics problems, their use as a general-purpose tool for scientific discovery is still in its infancy. Here, we approach this problem by modelling a neural network architecture…

Quantum Physics · Physics 2020-01-24 Raban Iten , Tony Metger , Henrik Wilming , Lidia del Rio , Renato Renner

This position paper argues that machine learning for scientific discovery should shift from inductive pattern recognition to axiom-based reasoning. We propose a game design framework in which scientific inquiry is recast as a rule-evolving…

Computational Engineering, Finance, and Science · Computer Science 2025-09-09 Pingchuan Ma , Benjamin Tod Jones , Tsun-Hsuan Wang , Minghao Guo , Michal Piotr Lipiec , Chuang Gan , Wojciech Matusik

Artificial intelligence systems for scientific discovery have demonstrated remarkable potential, yet existing approaches remain largely proprietary and operate in batch-processing modes requiring hours per research cycle, precluding…

Artificial Intelligence · Computer Science 2026-01-28 Lukas Weidener , Marko Brkić , Mihailo Jovanović , Ritvik Singh , Chiara Baccin , Emre Ulgac , Alex Dobrin , Aakaash Meduri

Even though superconductivity has been studied intensively for more than a century, the vast majority of superconductivity research today is carried out in nearly the same manner as decades ago. That is, each study tends to focus on only a…

Artificial intelligence (AI) has been increasingly applied in scientific activities for decades; however, it is still far from an insightful and trustworthy collaborator in the scientific process. Most existing AI methods are either too…

Artificial Intelligence · Computer Science 2022-02-08 Morad Behandish , John Maxwell , Johan de Kleer

We envision "AI scientists" as systems capable of skeptical learning and reasoning that empower biomedical research through collaborative agents that integrate AI models and biomedical tools with experimental platforms. Rather than taking…

AI research agents can now generate research ideas, design experiments, run code, and draft papers, raising the possibility of large-scale AI-assisted scientific discovery. Many current agent frameworks explicitly encourage the generation…

Computation and Language · Computer Science 2026-05-28 Yixuan Tang , Yi Yang

The last two decades have seen tremendous advances in Artificial Intelligence. The exponential growth in terms of computation capabilities has given us hope of developing humans like robots. The question is: are we there yet? Maybe not.…

Artificial Intelligence · Computer Science 2022-02-02 Madhav Agarwal , Siddhant Bansal

We analyze the challenges of benchmarking scientific (multi)-agentic systems, including the difficulty of distinguishing reasoning from retrieval, the risks of data/model contamination, the lack of reliable ground truth for novel research…

Computers and Society · Computer Science 2026-04-07 Marcin Abram

A close partnership between people and partially autonomous machines has enabled decades of space exploration. But to further expand our horizons, our systems must become more capable. Increasing the nature and degree of autonomy - allowing…

Scientific understanding is a fundamental goal of science, allowing us to explain the world. There is currently no good way to measure the scientific understanding of agents, whether these be humans or Artificial Intelligence systems.…

Artificial Intelligence · Computer Science 2024-05-07 Kristian Gonzalez Barman , Sascha Caron , Tom Claassen , Henk de Regt

Since its beginnings in the 1940s, automated reasoning by computers has become a tool of ever growing importance in scientific research. So far, the rules underlying automated reasoning have mainly been formulated by humans, in the form of…

Computers and Society · Computer Science 2025-10-20 Konrad Hinsen

Artificial intelligence (AI) is reshaping education, scientific training, and materials discovery. In materials science, AI models increasingly support property prediction, experiment prioritization, and hypothesis generation; however, the…

Physics Education · Physics 2026-05-12 Dongming Mei , Katherine Moore , Ben Sayler

Accelerated material discovery increasingly relies on artificial intelligence and machine learning, collectively termed "AI/ML". A key challenge in using AI is ensuring that human scientists trust the models are valid and reliable.…

Materials Science · Physics 2025-12-02 Benhour Amirian , Ashley S. Dale , Sergei Kalinin , Jason Hattrick-Simpers

A fascinating hypothesis is that human and animal intelligence could be explained by a few principles (rather than an encyclopedic list of heuristics). If that hypothesis was correct, we could more easily both understand our own…

Machine Learning · Computer Science 2022-08-02 Anirudh Goyal , Yoshua Bengio

This article explores the transformative impact of artificial intelligence (AI) on scientific research. It highlights ten ways in which AI is revolutionizing the work of scientists, including powerful referencing tools, improved…

General Literature · Computer Science 2023-07-21 César França

The emergence of large language models (LLMs) is propelling automated scientific discovery to the next level, with LLM-based Artificial Intelligence (AI) Scientist systems now taking the lead in scientific research. Several influential…

Artificial Intelligence · Computer Science 2025-08-04 Qiujie Xie , Yixuan Weng , Minjun Zhu , Fuchen Shen , Shulin Huang , Zhen Lin , Jiahui Zhou , Zilan Mao , Zijie Yang , Linyi Yang , Jian Wu , Yue Zhang

Scientific research is being reshaped by AI systems that move beyond isolated assistance toward longer-horizon workflows spanning literature grounding, hypothesis generation, experimentation, validation, reporting, and revision. This shift…

An activity fundamental to science is building mathematical models. These models are used to both predict the results of future experiments and gain insight into the structure of the system under study. We present an algorithm that…

Data Analysis, Statistics and Probability · Physics 2015-06-04 D. J. A. Hills , A. M. Grütter , J. J. Hudson