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Deep learning has led to a paradigm shift in artificial intelligence, including web, text and image search, speech recognition, as well as bioinformatics, with growing impact in chemical physics. Machine learning in general and deep…

One challenge of physics is to explain how collective properties arise from microscopic interactions. Indeed, interactions form the building blocks of almost all physical theories and are described by polynomial terms in the action. The…

Disordered Systems and Neural Networks · Physics 2023-05-03 Claudia Merger , Alexandre René , Kirsten Fischer , Peter Bouss , Sandra Nestler , David Dahmen , Carsten Honerkamp , Moritz Helias

Learning from data has led to paradigm shifts in a multitude of disciplines, including web, text, and image search, speech recognition, as well as bioinformatics. Can machine learning enable similar breakthroughs in understanding quantum…

The graph neural network (GNN) has been a powerful deep-learning tool in chemistry domain, due to its close connection with molecular graphs. Most GNN models collect and update atom and molecule features from the fed atom (and, in some…

Chemical Physics · Physics 2022-03-18 Yeji Kim , Yoonho Jeong , Jihoo Kim , Eok Kyun Lee , Won June Kim , Insung S. Choi

The task here is to predict the toxicological activity of chemical compounds based on the Tox21 dataset, a benchmark in computational toxicology. After a domain-specific overview of chemical toxicity, we discuss current computational…

Machine Learning · Computer Science 2025-10-28 Eduard Popescu , Adrian Groza , Andreea Cernat

Theoretical understanding of deep learning is one of the most important tasks facing the statistics and machine learning communities. While deep neural networks (DNNs) originated as engineering methods and models of biological networks in…

Machine Learning · Statistics 2018-06-04 Adam S. Charles

Recently, deep neural network (DNN)-based drug-target interaction (DTI) models were highlighted for their high accuracy with affordable computational costs. Yet, the models' insufficient generalization remains a challenging problem in the…

Biomolecules · Quantitative Biology 2021-12-14 Seokhyun Moon , Wonho Zhung , Soojung Yang , Jaechang Lim , Woo Youn Kim

Explainable ML for molecular toxicity prediction is a promising approach for efficient drug development and chemical safety. A predictive ML model of toxicity can reduce experimental cost and time while mitigating ethical concerns by…

Quantitative Methods · Quantitative Biology 2022-04-15 Bhanushee Sharma , Vijil Chenthamarakshan , Amit Dhurandhar , Shiranee Pereira , James A. Hendler , Jonathan S. Dordick , Payel Das

With access to large datasets, deep neural networks (DNN) have achieved human-level accuracy in image and speech recognition tasks. However, in chemistry, data is inherently small and fragmented. In this work, we develop an approach of…

Machine Learning · Statistics 2018-08-16 Garrett B. Goh , Charles Siegel , Abhinav Vishnu , Nathan O. Hodas

Progress in the application of machine learning techniques to the prediction of solid-state and molecular materials properties has been greatly facilitated by the development state-of-the-art feature representations and novel deep learning…

Materials Science · Physics 2022-03-21 David E. Sommer , Scott T. Dunham

Sentiment analysis is known as one of the most crucial tasks in the field of natural language processing and Convolutional Neural Network (CNN) is one of those prominent models that is commonly used for this aim. Although convolutional…

Computation and Language · Computer Science 2021-02-24 Hossein Sadr , Mozhdeh Nazari Solimandarabi , Mir Mohsen Pedram , Mohammad Teshnehlab

Machine-learning models in chemistry - when based on descriptors of atoms embedded within molecules - face essential challenges in transferring the quality of predictions of local electronic structures and their associated properties across…

Chemical Physics · Physics 2024-09-27 Frederik Ø. Kjeldal , Janus J. Eriksen

Predicting and enhancing inherent properties based on molecular structures is paramount to design tasks in medicine, materials science, and environmental management. Most of the current machine learning and deep learning approaches have…

Machine Learning · Computer Science 2024-04-08 Zachary R. Fox , Ayana Ghosh

With the rise of deep neural networks for quantum chemistry applications, there is a pressing need for architectures that, beyond delivering accurate predictions of chemical properties, are readily interpretable by researchers. Here, we…

Computational Physics · Physics 2018-06-28 Kristof T. Schütt , Michael Gastegger , Alexandre Tkatchenko , Klaus-Robert Müller

Data in tabular format is frequently occurring in real-world applications. Graph Neural Networks (GNNs) have recently been extended to effectively handle such data, allowing feature interactions to be captured through representation…

Machine Learning · Computer Science 2024-08-14 Amr Alkhatib , Sofiane Ennadir , Henrik Boström , Michalis Vazirgiannis

Improving diesel engine efficiency, reducing emissions, and enabling robust health monitoring have been critical research topics in engine modelling. While recent advancements in the use of neural networks for system monitoring have shown…

Machine Learning · Computer Science 2026-03-17 Kamaljyoti Nath , Varun Kumar , Daniel J. Smith , George Em Karniadakis

In this paper, we present an experiment on using deep learning and transfer learning techniques for emotion analysis in tweets and suggest a method to interpret our deep learning models. The proposed approach for emotion analysis combines a…

Computation and Language · Computer Science 2020-12-14 Yasas Senarath , Uthayasanker Thayasivam

Understanding and predicting the emergence of novel materials is a fundamental challenge in condensed matter physics, materials science and technology. With the rapid growth of materials databases in both size and reliability, the challenge…

Materials Science · Physics 2025-02-14 Jacopo Moi , Davide Spallarossa , Stefano Bonetti , Raffaella Burioni , Guido Caldarelli

Humans are able to explain their reasoning. On the contrary, deep neural networks are not. This paper attempts to bridge this gap by introducing a new way to design interpretable neural networks for classification, inspired by physiological…

Machine Learning · Statistics 2017-11-20 Shane Barratt

It is a critical challenge to simultaneously gain high interpretability and efficiency with the current schemes of deep machine learning (ML). Tensor network (TN), which is a well-established mathematical tool originating from quantum…

Quantum Physics · Physics 2023-11-21 Shi-Ju Ran , Gang Su
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