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Numerical simulations of the behavior of the osteonal structure are more and more acute and an important parameter is the pressure of the bony fluid. Haversian and Volkmann canals contain blood vessels that transport oxygen and nutrients…

Medical Physics · Physics 2010-05-28 Walid Miladi , Mihaela Racila

Background: Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia, affecting over 1% of the population. It is usually triggered by irregular electrical impulses that cause the atria to contract irregularly and…

Hepatic fibrosis causes an increase in liver stiffness, a parameter measured by elastography and widely used as a diagnosis method. The concomitant presence of portal vein thrombosis (PVT) implies a change in hepatic portal inflow that…

We report computational results of blood flow through a model of the human aortic arch and a vessel of actual diameter and length. On the top of the aortic arch the branching of the %%three arteries are included: the subclavian and jugular.…

Fluid Dynamics · Physics 2008-11-11 Renat A. Sultanov , Dennis Guster

Around the third week after gestation in embryonic development, the human heart consists only of a valvless tube, unlike a fully developed adult heart, which is multi-chambered. At this stage in development, the heart valves have not formed…

Tissues and Organs · Quantitative Biology 2018-09-19 Nicholas A. Battista , Andrea N. Lane , Laura A. Miller

Blood pressure regulation is commonly addressed in terms of local mechanisms such as vascular resistance, compliance and neurohumoral control. However, the human vasculature encompasses multiple quasi-closed flow loops under both…

Medical Physics · Physics 2026-02-11 Arturo Tozzi

Analysing the haemodynamics of flow in carotid artery disease serves as a means to better understand the development and progression of associated complex diseases. Carotid artery disease can predispose people to major adverse…

Arterial biomechanical indicators have long been recognized as fundamental contributors to the physiology and pathology of cardiovascular systems. Probing the multiple biomechanical parameters of arteries simultaneously at different time…

It has been shown that geometrical, structural properties vary along the length of the aortic arch. There is a scarcity of studies focus on the variation in the vessel wall thickness of aortic arch. The central premise of this study is that…

Tissues and Organs · Quantitative Biology 2018-06-21 Xiaochang Leng , Xingjian Liu , Will Toress , Tarek Shazly

With the development of additive manufacturing, 3D printing technology has become more common nowadays. We designed and 3D printed a cost-effective liquid fluid pressure measurement device that can convert liquid pressure to air pressure.…

Medical Physics · Physics 2019-10-25 Yuqi Jin , Akansha Rao , William Brinkman , Tae-Youl Choi

Numerical simulations of pulsatile blood flow in an aortic coarctation require the use of turbulence modeling. This paper considers three models from the class of large eddy simulation (LES) models (Smagorinsky, Vreman,…

Computational Engineering, Finance, and Science · Computer Science 2022-09-02 Sarah Katz , Alfonso Caiazzo , Baptiste Moreau , Ulrich Wilbrandt , Jan Brüning , Leonid Goubergrits , Volker John

Non-stationarity is the rule in the atmospheric boundary layer (ABL). Under such conditions, the flow may experience departures from equilibrium with the underlying surface stress, misalignment of shear stresses and strain rates, and…

Fluid Dynamics · Physics 2023-07-27 Weiyi Li , Marco G. Giometto

Using analytical expressions for the pressure and velocity waveforms in tapered vessels, we construct a linear 1D model for wave propagation in stenotic vessels in the frequency domain. We demonstrate that using only two parameters to…

Fluid Dynamics · Physics 2019-07-24 George Papadakis , Jean Raspaud

Mathematical models are widely recognized as a valuable tool for cardiovascular diagnosis and the study of circulatory diseases, especially to obtain data that require otherwise invasive measurements. To correctly simulate body…

Bicuspid valves with crescent-shaped leaflets are found in lymphatic vessels and veins, where their primary function is to prevent reflux and ensure unidirectional flow toward the heart. These valves are passive, and their functionality…

Fluid Dynamics · Physics 2026-04-14 B. Kaoui , A. Bou Orm , P. Navet , J. Baish , L. L. Munn

The aim of this Letter is to characterize the flow regimes of suspensions of finite-size rigid particles in a viscous fluid at finite inertia. We explore the system behavior as function of the particle volume fraction and the Reynolds…

Fluid Dynamics · Physics 2015-06-18 Iman Lashgari , Francesco Picano , Wim-Paul Breugem , Luca Brandt

Disruptions in the normal rhythmic functioning of the heart, termed as arrhythmia, often result from qualitative changes in the excitation dynamics of the organ. The transitions between different types of arrhythmia are accompanied by…

Tissues and Organs · Quantitative Biology 2016-01-21 Pavithraa Seenivasan , Soumya Easwaran , S. Sridhar , Sitabhra Sinha

We analyse mathematical models in order to understand how microstructural features of vascular networks may affect blood-flow dynamics, and to identify particular characteristics that promote the onset of self-sustained oscillations. By…

Quantitative Methods · Quantitative Biology 2022-06-23 Yaron Ben-Ami , George W. Atkinson , Joe M. Pitt-Francis , Philip K. Maini , Helen M. Byrne

Coronary heart disease (CHD) remains a leading cause of mortality worldwide. This study introduces a novel approach that integrates patient-specific Multi-slice CT scans into CAD models, using a one-dimensional numerical framework to assess…

Medical Physics · Physics 2025-05-21 Priyanshu Ghosh , Sayan Karmakar , Disha Mondal , Oeshee Roy , Supratim Saha

Cardiovascular diseases are a leading cause of death globally. Among them, some are linked to stenosis, which is an abnormal narrowing of blood vessels, as well as other factors. Smart drug delivery systems based on micro- and nanoparticles…

Fluid Dynamics · Physics 2025-11-18 R. Dapena-García , V. Pérez-Muñuzuri