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In recent years, code security has become increasingly important, especially with the rise of interconnected technologies. Detecting vulnerabilities early in the software development process has demonstrated numerous benefits. Consequently,…

Software Engineering · Computer Science 2024-07-22 José Gonçalves , Tiago Dias , Eva Maia , Isabel Praça

High-quality evaluation benchmarks are pivotal for deploying Large Language Models (LLMs) in Automated Code Review (ACR). However, existing benchmarks suffer from two critical limitations: first, the lack of multi-language support in…

Background: While the importance of gene-gene interactions in human diseases has been well recognized, identifying them has been a great challenge, especially through association studies with millions of genetic markers and thousands of…

Quantitative Methods · Quantitative Biology 2015-05-07 Changshuai Wei , Qing Lu

With the rise of large language models (LLMs), recent works have leveraged LLMs to improve the performance of click-through rate (CTR) prediction. However, we argue that a critical obstacle remains in deploying LLMs for practical use: the…

Information Retrieval · Computer Science 2024-03-29 Binzong Geng , Zhaoxin Huan , Xiaolu Zhang , Yong He , Liang Zhang , Fajie Yuan , Jun Zhou , Linjian Mo

Relative Lempel-Ziv (RLZ) is a popular algorithm for compressing databases of genomes from individuals of the same species when fast random access is desired. With Kuruppu et al.'s (SPIRE 2010) original implementation, a reference genome is…

Data Structures and Algorithms · Computer Science 2016-05-17 Anthony J. Cox , Andrea Farruggia , Travis Gagie , Simon J. Puglisi , Jouni Sirén

Large language models (LLMs) are increasingly used for generating parallel scientific codes, with a primary focus on generating functionally correct code. Recent work has focused on generating performant code, with an emphasis on its…

Artificial Intelligence · Computer Science 2026-05-12 Matthew T. Dearing , Yiheng Tao , Xingfu Wu , Zhiling Lan , Valerie Taylor

With the increasing affordability and accessibility of genome sequencing data, de novo genome assembly is an important first step to a wide variety of downstream studies and analyses. Therefore, bioinformatics tools that enable the…

Genomics · Quantitative Biology 2023-06-09 Lauren Coombe , René L. Warren , Johnathan Wong , Vladimir Nikolic , Inanc Birol

The security of code generated by large language models (LLMs) is a significant concern, as studies indicate that such code often contains vulnerabilities and lacks essential defensive programming constructs. This work focuses on examining…

Artificial Intelligence · Computer Science 2025-11-25 Muhammad Usman Shahid , Chuadhry Mujeeb Ahmed , Rajiv Ranjan

We present DASH, a C++ template library that offers distributed data structures and parallel algorithms and implements a compiler-free PGAS (partitioned global address space) approach. DASH offers many productivity and performance features…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-10-06 Karl Fürlinger , Tobias Fuchs , Roger Kowalewski

The tremdendous advances in high-throughput sequencing technologies have made population-scale sequencing as performed in the 1000 Genomes project and the Genome of the Netherlands project possible. Next-generation sequencing has allowed…

Genomics · Quantitative Biology 2013-03-15 Tobias Marschall , Alexander Schönhuth

Generative Large Language Models (LLMs) are a promising approach to structuring knowledge contained within the corpora of research literature produced by large-scale and long-running scientific collaborations. Within experimental particle…

High Energy Physics - Experiment · Physics 2025-09-09 James McGreivy , Blaise Delaney , Anja Beck , Mike Williams

The increasing complexity of modern software systems exacerbates the prevalence of security vulnerabilities, posing risks of severe breaches and substantial economic loss. Consequently, robust code vulnerability detection is essential for…

Cryptography and Security · Computer Science 2025-10-09 Zhiyuan Wei , Xiaoxuan Yang , Jing Sun , Zijian Zhang

Massively parallel sequencing techniques have revolutionized biological and medical sciences by providing unprecedented insight into the genomes of humans, animals, and microbes. Modern sequencing platforms generate enormous amounts of…

We present four main contributions to enhance the performance of Large Language Models (LLMs) in generating domain-specific code: (i) utilizing LLM-based data splitting and data renovation techniques to improve the semantic representation…

Computation and Language · Computer Science 2024-01-31 Yu-Chen Lin , Akhilesh Kumar , Norman Chang , Wenliang Zhang , Muhammad Zakir , Rucha Apte , Haiyang He , Chao Wang , Jyh-Shing Roger Jang

RNA sequencing (RNA-seq) enables characterization and quantification of individual transcriptomes as well as detection of patterns of allelic expression and alternative splicing. Current RNA-seq protocols depend on high-throughput…

Genomics · Quantitative Biology 2015-06-19 Hyunghoon Cho , Joe Davis , Xin Li , Kevin S. Smith , Alexis Battle , Stephen B. Montgomery

Deep regression networks are widely used to tackle the problem of predicting a continuous value for a given input. Task-specialized approaches for training regression networks have shown significant improvement over generic approaches, such…

Machine Learning · Computer Science 2023-03-07 Deval Shah , Tor M. Aamodt

Large Language Models (LLMs) are increasingly being leveraged for generating and translating scientific computer codes by both domain-experts and non-domain experts. Fortran has served as one of the go to programming languages in legacy…

Motivation: Data volumes generated by next-generation sequencing technolo- gies is now a major concern, both for storage and transmission. This triggered the need for more efficient methods than general purpose compression tools, such as…

Data Structures and Algorithms · Computer Science 2014-12-19 Gaëtan Benoit , Claire Lemaitre , Dominique Lavenier , Guillaume Rizk

Large Language Models (LLMs) often struggle with code generation tasks involving niche software libraries. Existing code generation techniques with only human-oriented documentation can fail -- even when the LLM has access to web search and…

Software Engineering · Computer Science 2025-05-09 Sandya Wijaya , Jacob Bolano , Alejandro Gomez Soteres , Shriyanshu Kode , Yue Huang , Anant Sahai

Building officials, particularly those in resource-constrained or rural jurisdictions, face labor-intensive, error-prone, and costly manual reviews of design documents as projects increase in size and complexity. The growing adoption of…

Software Engineering · Computer Science 2025-10-06 Hanlong Wan , Weili Xu , Michael Rosenberg , Jian Zhang , Aysha Siddika