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The performance of deep neural networks typically increases with the number of training images. However, not all images have the same importance towards improved performance and robustness. In fetal brain MRI, abnormalities exacerbate the…

Dealing with atypical traffic scenarios remains a challenging task in autonomous driving. However, most anomaly detection approaches cannot be trained on raw sensor data but require exposure to outlier data and powerful semantic…

Computer Vision and Pattern Recognition · Computer Science 2024-10-02 Daniel Bogdoll , Noël Ollick , Tim Joseph , Svetlana Pavlitska , J. Marius Zöllner

Obtaining labels for medical (image) data requires scarce and expensive experts. Moreover, due to ambiguous symptoms, single images rarely suffice to correctly diagnose a medical condition. Instead, it often requires to take additional…

Image and Video Processing · Electrical Eng. & Systems 2020-11-05 Diana Davletshina , Valentyn Melnychuk , Viet Tran , Hitansh Singla , Max Berrendorf , Evgeniy Faerman , Michael Fromm , Matthias Schubert

Quantification of anatomical shape changes currently relies on scalar global indexes which are largely insensitive to regional or asymmetric modifications. Accurate assessment of pathology-driven anatomical remodeling is a crucial step for…

Statistical analysis of magnetic resonance imaging (MRI) can help radiologists to detect pathologies that are otherwise likely to be missed. Deep learning (DL) has shown promise in modeling complex spatial data for brain anomaly detection.…

Computer Vision and Pattern Recognition · Computer Science 2020-11-26 Victor Saase , Holger Wenz , Thomas Ganslandt , Christoph Groden , Máté E. Maros

As digital medical imaging becomes more prevalent and archives increase in size, representation learning exposes an interesting opportunity for enhanced medical decision support systems. On the other hand, medical imaging data is often…

Computer Vision and Pattern Recognition · Computer Science 2018-07-25 Eduardo Pinho , Carlos Costa

Detection of various lesions in brain MRI is clinically critical, but challenging due to the diversity of lesions and variability in imaging conditions. Current unsupervised learning methods detect anomalies mainly through reconstructing…

Computer Vision and Pattern Recognition · Computer Science 2025-12-29 Tao Yang , Xiuying Wang , Hao Liu , Guanzhong Gong , Lian-Ming Wu , Yu-Ping Wang , Lisheng Wang

In medical imaging, obtaining large amounts of labeled data is often a hurdle, because annotations and pathologies are scarce. Anomaly detection is a method that is capable of detecting unseen abnormal data while only being trained on…

Computer Vision and Pattern Recognition · Computer Science 2022-06-09 Djennifer K. Madzia-Madzou , Hugo J. Kuijf

The application of supervised models to clinical screening tasks is challenging due to the need for annotated data for each considered pathology. Unsupervised Anomaly Detection (UAD) is an alternative approach that aims to identify any…

Image and Video Processing · Electrical Eng. & Systems 2025-01-24 Finn Behrendt , Debayan Bhattacharya , Robin Mieling , Lennart Maack , Julia Krüger , Roland Opfer , Alexander Schlaefer

Inspired by recent findings that generative diffusion models learn semantically meaningful representations, we use them to discover the intrinsic hierarchical structure in biomedical 3D images using unsupervised segmentation. We show that…

Computer Vision and Pattern Recognition · Computer Science 2023-10-11 Nurislam Tursynbek , Marc Niethammer

Using deep learning techniques, anomalies in the paranasal sinus system can be detected automatically in MRI images and can be further analyzed and classified based on their volume, shape and other parameters like local contrast. However…

Unsupervised anomaly detection in medical imaging aims to detect and localize arbitrary anomalies without requiring annotated anomalous data during training. Often, this is achieved by learning a data distribution of normal samples and…

Computer Vision and Pattern Recognition · Computer Science 2023-01-06 Carsten T. Lüth , David Zimmerer , Gregor Koehler , Paul F. Jaeger , Fabian Isensee , Jens Petersen , Klaus H. Maier-Hein

Medical segmentation is performed to determine the bounds of regions of interest (ROI) prior to surgery. By allowing the study of growth, structure, and behaviour of the ROI in the planning phase, critical information can be obtained,…

Image and Video Processing · Electrical Eng. & Systems 2020-10-06 Bao Nguyen , Adam Feldman , Sarath Bethapudi , Andrew Jennings , Chris G. Willcocks

With the rising demands for robust structural health monitoring procedures for aerospace structures, the scope of intelligent algorithms and learning techniques is expanding. Supervised algorithms have shown promising results in the field…

Signal Processing · Electrical Eng. & Systems 2023-08-11 Mahindra Rautela , Amin Maghareh , Shirley Dyke , S. Gopalakrishnan

Anomaly detection and classification in medical imaging are critical for early diagnosis but remain challenging due to limited annotated data, class imbalance, and the high cost of expert labeling. Emerging vision foundation models such as…

Image and Video Processing · Electrical Eng. & Systems 2025-09-17 Fazle Rafsani , Jay Shah , Catherine D. Chong , Todd J. Schwedt , Teresa Wu

Unsupervised anomaly detection methods offer a promising and flexible alternative to supervised approaches, holding the potential to revolutionize medical scan analysis and enhance diagnostic performance. In the current landscape, it is…

Image and Video Processing · Electrical Eng. & Systems 2023-08-29 Cosmin I. Bercea , Esther Puyol-Antón , Benedikt Wiestler , Daniel Rueckert , Julia A. Schnabel , Andrew P. King

Anomaly detection for Magnetic Resonance Images (MRIs) can be solved with unsupervised methods by learning the distribution of healthy images and identifying anomalies as outliers. In presence of an additional dataset of unlabelled data…

Machine Learning · Computer Science 2020-07-27 Alexandra-Ioana Albu , Alina Enescu , Luigi Malagò

3D medical image segmentation is a challenging task with crucial implications for disease diagnosis and treatment planning. Recent advances in deep learning have significantly enhanced fully supervised medical image segmentation. However,…

Image and Video Processing · Electrical Eng. & Systems 2025-06-23 Runmin Jiang , Zhaoxin Fan , Junhao Wu , Lenghan Zhu , Xin Huang , Tianyang Wang , Heng Huang , Min Xu

Unsupervised anomaly detection in brain images is crucial for identifying injuries and pathologies without access to labels. However, the accurate localization of anomalies in medical images remains challenging due to the inherent…

Computer Vision and Pattern Recognition · Computer Science 2025-07-25 Farzad Beizaee , Gregory Lodygensky , Christian Desrosiers , Jose Dolz

Unsupervised anomaly detection (UAD) aims to detect anomalies without labeled data, a necessity in many machine learning applications where anomalous samples are rare or not available. Most state-of-the-art methods fall into two categories:…

Machine Learning · Computer Science 2025-07-30 Nicolas Pinon , Carole Lartizien