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We study the cosmological information of weak lensing (WL) peaks, focusing on two other statistics besides their abundance: the stacked tangential-shear profiles and the peak-peak correlation function. We use a large ensemble of simulated…

Cosmology and Nongalactic Astrophysics · Physics 2015-06-12 Laura Marian , Robert E. Smith , Stefan Hilbert , Peter Schneider

Topological phylogenetic trees can be assigned edge weights in several natural ways, highlighting different aspects of the tree. Here the rooted triple and quartet metrizations are introduced, and applied to formulate novel fast methods of…

Populations and Evolution · Quantitative Biology 2019-05-15 John A. Rhodes

Coalescent processes, including mutation, are derived from Moran type population models admitting large offspring numbers. Including mutation in the coalescent process allows for quantifying the turnover of alleles by computing the…

Populations and Evolution · Quantitative Biology 2012-12-11 Bjarki Eldon

We consider Beta$(2-\alpha, \alpha)$-coalescents with parameter range $1 <\alpha<2$ starting from $n$ leaves. The length $\ell^{(n)}_r$ of order $r$ in the $n$-Beta$(2-\alpha, \alpha)$-coalescent tree is defined as the sum of the lengths of…

Probability · Mathematics 2022-11-30 Matthias Birkner , Iulia Dahmer , Christina S. Diehl , Götz Kersting

We study the role of phylogenetic trees on correlations in mutation processes. Generally, correlations decay exponentially with the generation number. We find that two distinct regimes of behavior exist. For mutation rates smaller than a…

Statistical Mechanics · Physics 2009-10-31 E. Ben-Naim , A. S. Lapedes

Phylogenetic comparative methods are well established tools for using inter-species variation to analyse phenotypic evolution and adaptation. They are generally hampered, however, by predominantly univariate approaches and failure to…

Populations and Evolution · Quantitative Biology 2024-12-13 Krzysztof Bartoszek

We consider large uniform random trees where we fix for each vertex its degree and height. We prove, under natural conditions of convergence for the profile, that those trees properly renormalized converge. To this end, we study the paths…

Probability · Mathematics 2026-03-06 Arthur Blanc-Renaudie , Emmanuel Kammerer

High-dimensional phenotypes hold promise for richer findings in association studies, but testing of several phenotype traits aggravates the grand challenge of association studies, that of multiple testing. Several methods have recently been…

Methodology · Statistics 2013-05-14 Pekka Marttinen , Jussi Gillberg , Aki Havulinna , Jukka Corander , Samuel Kaski

Computational inference of dated evolutionary histories relies upon various hypotheses about RNA, DNA, and protein sequence mutation rates. Using mutation rates to infer these dated histories is referred to as molecular clock assumption.…

Populations and Evolution · Quantitative Biology 2021-01-11 Lena Collienne , Kieran Elmes , Mareike Fischer , David Bryant , Alex Gavryushkin

Estimating phylogenetic trees is an important problem in evolutionary biology, environmental policy and medicine. Although trees are estimated, their uncertainties are discarded by mathematicians working in tree space. Here we explicitly…

Methodology · Statistics 2017-10-16 Amy D. Willis , Rayna C. Bell

Estimating the phylogeny of the genus Homo is entering a new phase of vastly improved data and methodology. There is increasing evidence of 6 to 10 competing species/lineages at any point in the last half million years, making the…

Populations and Evolution · Quantitative Biology 2017-01-02 Peter J. Waddell

Hierarchical autocorrelation in the error term of linear models arises when sampling units are related to each other according to a tree. The residual covariance is parametrized using the tree-distance between sampling units. When…

Statistics Theory · Mathematics 2013-08-09 Lam Si Tung Ho , Cécile Ané

Human aging is a process controlled by both genetics and environment. Many studies have been conducted to identify a subset of genes related to aging from the human genome. Biologists implicitly categorize age-related genes into genes that…

Genomics · Quantitative Biology 2023-11-17 Salman Mohamadi , Donald A. Adjeroh

The reconstruction of a species phylogeny from genomic data faces two significant hurdles: 1) the trees describing the evolution of each individual gene--i.e., the gene trees--may differ from the species phylogeny and 2) the molecular…

Machine Learning · Computer Science 2017-07-17 Gautam Dasarathy , Elchanan Mossel , Robert Nowak , Sebastien Roch

Take a continuous-time Galton-Watson tree. If the system survives until a large time $T$, then choose $k$ particles uniformly from those alive. What does the ancestral tree drawn out by these $k$ particles look like? Some special cases are…

Probability · Mathematics 2019-02-14 Simon C. Harris , Samuel G. G. Johnston , Matthew I. Roberts

The correlation among the gene genealogies at different loci is crucial in biology, yet challenging to understand because such correlation depends on many factors including genetic linkage, recombination, natural selection and population…

Probability · Mathematics 2023-10-20 David Kogan , Dimitrios Diamantidis , John Wakeley , Wai-Tong Louis Fan

The reconstruction of a species tree from genomic data faces a double hurdle. First, the (gene) tree describing the evolution of each gene may differ from the species tree, for instance, due to incomplete lineage sorting. Second, the…

Populations and Evolution · Quantitative Biology 2021-12-07 Sebastien Roch , Mike Steel

Mounting evidence suggests that natural populations can harbor extensive fitness diversity with numerous genomic loci under selection. It is also known that genealogical trees for populations under selection are quantifiably different from…

Populations and Evolution · Quantitative Biology 2013-01-04 Adel Dayarian , Boris I Shraiman

We introduce a new model of correlated randomly growing graphs and study the fundamental questions of detecting correlation and estimating aspects of the correlated structure. The model is simple and starts with any model of randomly…

Probability · Mathematics 2020-04-29 Miklos Z. Racz , Anirudh Sridhar

Bayesian inference is now a leading technique for reconstructing phylogenetic trees from aligned sequence data. In this short note, we formally show that the maximum posterior tree topology provides a statistically consistent estimate of a…

Populations and Evolution · Quantitative Biology 2013-07-12 Mike Steel