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Multimodal single-cell technologies enable the simultaneous collection of diverse data types from individual cells, enhancing our understanding of cellular states. However, the integration of these datatypes and modeling the…

Machine Learning · Computer Science 2023-11-22 Bhavya Mehta , Nirmit Deliwala , Madhav Chandane

A quantitative model of the mobility of functionalized particles at the interface is pivotal to understanding important systems in biology and nanotechnology. In this work, we investigate the emerging dynamics of particles anchored through…

Soft Condensed Matter · Physics 2024-06-19 Janna Lowensohn , Laurie Stevens , Daniel Goldstein , Bortolo Matteo Mognetti

Accurate measurements of kinetic rate constants for interacting biomolecules is crucial for understanding the mechanisms underlying intracellular signalling pathways. The magnitude of binding rates plays a very important molecular…

Quantitative Methods · Quantitative Biology 2013-12-02 Hugo B. Brandao , Hussain Sangji , Elvis Pandzic , Susanne Bechstedt , Gary J. Brouhard , Paul W. Wiseman

In solution, electrically like-charged particles can experience a strong and long-ranged attraction that leads to the formation of stable, slowly reorganizing clusters. The attractive force underpinning this spontaneous organization process…

Soft Condensed Matter · Physics 2026-01-14 Sida Wang , Angela Le , Rowan Walker-Gibbons , Madhavi Krishnan

Colloidal systems find important applications ranging from fabrication of photonic crystals to direct probing of phenomena typically encountered in atomic crystals and glasses. New applications - such as nanoantennas, plasmonic sensors, and…

Soft Condensed Matter · Physics 2016-12-30 Rahul P. Trivedi , Ivan I. Klevets , Bohdan Senyuk , Taewoo Lee , Ivan I. Smalyukh

The interplay of membrane proteins is vital for many biological processes, such as cellular transport, cell division, and signal transduction between nerve cells. Theoretical considerations have led to the idea that the membrane itself…

Soft Condensed Matter · Physics 2016-11-28 Casper van der Wel , Afshin Vahid , Anđela Šarić , Timon Idema , Doris Heinrich , Daniela J. Kraft

Soft particles display highly versatile properties with respect to hard colloids, even more so at fluid-fluid interfaces. In particular, microgels, consisting of a cross-linked polymer network, are able to deform and flatten upon adsorption…

The superimposed pilot transmission scheme offers substantial potential for improving spectral efficiency in MIMO-OFDM systems, but it presents significant challenges for receiver design due to pilot contamination and data interference. To…

Information Theory · Computer Science 2025-07-15 Xinjie Li , Xingyu Zhou , Yixiao Cao , Jing Zhang , Chao-Kai Wen , Xiao Li , Shi Jin

Strongly correlated systems containing d/f-electrons present a challenge to conventional density functional theory (DFT), such as the widely used local density approximation (LDA) or generalized gradient approximation (GGA). In this work,…

Strongly Correlated Electrons · Physics 2024-01-19 Bei-Lei Liu , Yue-Chao Wang , Yu Liu , Hai-Feng Liu , Hai-Feng Song

Protein-ligand binding is the process by which a small molecule (drug or inhibitor) attaches to a target protein. Binding affinity, which characterizes the strength of biomolecular interactions, is essential for tackling diverse challenges…

This study investigates the interplay between Strong Coupling (SC) attraction and hydration repulsion in nanoconfined water between like-charged phospholipid layers. It challenges the assumption that SC attraction requires multivalent…

Recent progress on saliency detection is substantial, benefiting mostly from the explosive development of Convolutional Neural Networks (CNNs). Semantic segmentation and saliency detection algorithms developed lately have been mostly based…

Computer Vision and Pattern Recognition · Computer Science 2018-03-19 Qibin Hou , Ming-Ming Cheng , Xiao-Wei Hu , Ali Borji , Zhuowen Tu , Philip Torr

Detecting and segmenting object instances is a common task in biomedical applications. Examples range from detecting lesions on functional magnetic resonance images, to the detection of tumours in histopathological images and extracting…

Computer Vision and Pattern Recognition · Computer Science 2021-04-12 Tim Prangemeier , Christoph Reich , Heinz Koeppl

Inferring biological relationships from cellular phenotypes in high-content microscopy screens provides significant opportunity and challenge in biological research. Prior results have shown that deep vision models can capture biological…

Deep convolutional neural networks have been widely applied in salient object detection and have achieved remarkable results in this field. However, existing models suffer from information distortion caused by interpolation during…

Computer Vision and Pattern Recognition · Computer Science 2023-12-01 Hewen Xiao , Jie Mei , Guangfu Ma , Weiren Wu

Surface lattice resonances (SLRs) in metasurfaces have become a transformative platform for subwavelength optical devices, leveraging their high quality (Q)-factors, pronounced local field enhancement, and extensive long-range interactions.…

Interactions between particles in quantum many-body systems play a crucial role in determining the electric, magnetic, optical, and thermal properties of the system. The recent progress in the laser-pulse technique has enabled the…

Strongly Correlated Electrons · Physics 2021-09-07 Nguyen Thanh Phuc , Pham Quang Trung

This paper presents a co-salient object detection method to find common salient regions in a set of images. We utilize deep saliency networks to transfer co-saliency prior knowledge and better capture high-level semantic information, and…

Computer Vision and Pattern Recognition · Computer Science 2018-10-17 Dong-ju Jeong , Insung Hwang , Nam Ik Cho

Binding of particles through weak (non-covalent) interactions plays a central role in multiple modern disciplines, from Cooper pairing of electrons in superconductivity to formation of supramolecules in biochemistry. Optical solitons, which…

Optics · Physics 2018-08-03 W. He , M. Pang , D. H. Yeh , J. Huang , C. R. Menyuk , P. St. J. Russell

We present a simple, modular graph-based convolutional neural network that takes structural information from protein-ligand complexes as input to generate models for activity and binding mode prediction. Complex structures are generated by…

Biomolecules · Quantitative Biology 2020-02-26 Joseph A. Morrone , Jeffrey K. Weber , Tien Huynh , Heng Luo , Wendy D. Cornell