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The problem of computing an exact experimental design that is optimal for the least-squares estimation of the parameters of a regression model is considered. We show that this problem can be solved via mixed-integer linear programming…

Computation · Statistics 2024-06-18 Radoslav Harman , Samuel Rosa

A decision support system relies on frequent re-solving of similar problem instances. While the general structure remains the same in corresponding applications, the input parameters are updated on a regular basis. We propose a generative…

Optimization and Control · Mathematics 2021-02-04 Lovis Anderson , Mark Turner , Thorsten Koch

In this paper, we propose a new mixed-integer linear programming (MILP) model ontology and a novel constraint typology of MILP formulations. MILP is a commonly used mathematical programming technique for modelling and solving real-life…

Artificial Intelligence · Computer Science 2021-03-02 Bahadorreza Ofoghi , Vicky Mak , John Yearwood

Following the recent push for trustworthy AI, there has been an increasing interest in developing contrastive explanation techniques for optimisation, especially concerning the solution of specific decision-making processes formalised as…

Artificial Intelligence · Computer Science 2025-07-18 Roger Xavier Lera-Leri , Filippo Bistaffa , Athina Georgara , Juan Antonio Rodriguez-Aguilar

Mixed Integer Linear Programming (MILP) is a fundamental class of NP-hard problems that has garnered significant attention from both academia and industry. The Branch-and-Bound (B\&B) method is the dominant approach for solving MILPs and…

Machine Learning · Computer Science 2025-11-27 Tongkai Lu , Shuai Ma , Chongyang Tao

This applied research article explores the application of Mixed-Integer Linear Programming (MILP) to address line-balancing challenges in the garment industry, focusing on optimizing production processes under multiple constraints. By…

Optimization and Control · Mathematics 2025-04-10 Ray Wai Man Kong , Ding Ning , Theodore Ho Tin Kong

Optimal planning with respect to learned neural network (NN) models in continuous action and state spaces using mixed-integer linear programming (MILP) is a challenging task for branch-and-bound solvers due to the poor linear relaxation of…

Artificial Intelligence · Computer Science 2019-07-29 Buser Say , Scott Sanner , Sylvie Thiébaux

Designing faster algorithms for solving Mixed-Integer Linear Programming (MILP) problems is highly desired across numerous practical domains, as a vast array of complex real-world challenges can be effectively modeled as MILP formulations.…

Artificial Intelligence · Computer Science 2026-01-23 Ruizhi Liu , Liming Xu , Xulin Huang , Jingyan Sui , Shizhe Ding , Boyang Xia , Chungong Yu , Dongbo Bu

The alternating-current unit commitment problem provides a realistic representation of power system operations, which is a nonconvex mixed-integer nonlinear programming problem and hence is computationally intractable. A common relaxation…

Optimization and Control · Mathematics 2026-04-07 Yongzheng Dai

Over the past few decades, neuroscience experiments have become increasingly complex and naturalistic. Experimental design has in turn become more challenging, as experiments must conform to an ever-increasing diversity of design…

Neurons and Cognition · Quantitative Biology 2020-12-07 Storm Slivkoff , Jack L. Gallant

Discrete black-box optimization problems are challenging for model-based optimization (MBO) algorithms, such as Bayesian optimization, due to the size of the search space and the need to satisfy combinatorial constraints. In particular,…

Optimization and Control · Mathematics 2022-06-15 Theodore Papalexopoulos , Christian Tjandraatmadja , Ross Anderson , Juan Pablo Vielma , David Belanger

Mixed Integer Linear Programs (MILPs) are highly flexible and powerful tools for modeling and solving complex real-world combinatorial optimization problems. Recently, machine learning (ML)-guided approaches have demonstrated significant…

Artificial Intelligence · Computer Science 2025-06-13 Junyang Cai , Taoan Huang , Bistra Dilkina

Influence diagrams represent decision-making problems with interdependencies between random events, decisions, and consequences. Traditionally, they have been solved using algorithms that determine the expected utility-maximizing decision…

Optimization and Control · Mathematics 2026-01-14 Topias Terho , Fabricio Oliveira , Ahti Salo , Pedro Munari

This paper deals with a distributed Mixed-Integer Linear Programming (MILP) set-up arising in several control applications. Agents of a network aim to minimize the sum of local linear cost functions subject to both individual constraints…

Optimization and Control · Mathematics 2021-02-12 Andrea Camisa , Ivano Notarnicola , Giuseppe Notarstefano

In this paper we deal with a network of agents seeking to solve in a distributed way Mixed-Integer Linear Programs (MILPs) with a coupling constraint (modeling a limited shared resource) and local constraints. MILPs are NP-hard problems and…

Systems and Control · Computer Science 2020-10-28 Andrea Camisa , Ivano Notarnicola , Giuseppe Notarstefano

For clustering of an undirected graph, this paper presents an exact algorithm for the maximization of modularity density, a more complicated criterion to overcome drawbacks of the well-known modularity. The problem can be interpreted as the…

Social and Information Networks · Computer Science 2017-06-28 Keisuke Sato , Yoichi Izunaga

Leveraging machine learning (ML) to predict an initial solution for mixed-integer linear programming (MILP) has gained considerable popularity in recent years. These methods predict a solution and fix a subset of variables to reduce the…

Machine Learning · Computer Science 2025-03-04 Haoyang Liu , Jie Wang , Zijie Geng , Xijun Li , Yuxuan Zong , Fangzhou Zhu , Jianye Hao , Feng Wu

Mixed Integer Linear Programming (MILP) is a fundamental tool for modeling combinatorial optimization problems. Recently, a growing body of research has used machine learning to accelerate MILP solving. Despite the increasing popularity of…

Machine Learning · Computer Science 2024-10-29 Weimin Huang , Taoan Huang , Aaron M Ferber , Bistra Dilkina

Mixed-Integer Linear Programming (MILP) is widely used in fields such as scheduling, logistics, and planning. Enhancing the performance of MILP solvers, particularly learning-based solvers, requires substantial amounts of high-quality data.…

Optimization and Control · Mathematics 2025-05-20 Tianxing Yang , Huigen Ye , Hua Xu

Data-driven inverse optimization for mixed-integer linear programs (MILPs), which seeks to learn an objective function and constraints consistent with observed decisions, is important for building accurate mathematical models in a variety…

Optimization and Control · Mathematics 2026-02-17 Akira Kitaoka