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In this study, we present a novel molecular fingerprint generation method based on multiparameter persistent homology. This approach reveals the latent structures and relationships within molecular geometry, and detects topological features…

Biomolecules · Quantitative Biology 2023-11-21 Andac Demir , Bulent Kiziltan

We present a machine learning approach that leverages persistent homology to classify bacterial flagellar motors into two functional states: rotated and stalled. By embedding protein structural data into a topological framework, we extract…

Biomolecules · Quantitative Biology 2025-12-19 Zakaria Lamine , Abdelatif Hafid , Mohamed Rahouti

The object recognition is a complex problem in the image processing. Mathematical morphology is Shape oriented operations, that simplify image data, preserving their essential shape characteristics and eliminating irrelevancies. This paper…

Computer Vision and Pattern Recognition · Computer Science 2015-07-28 R. P. Prakash , Keerthana S. Prakash , V. P. Binu

Statistical analysis on object data presents many challenges. Basic summaries such as means and variances are difficult to compute. We apply ideas from topology to study object data. We present a framework for using persistence landscapes…

Methodology · Statistics 2019-12-12 Vic Patrangenaru , Peter Bubenik , Robert L. Paige , Daniel Osborne

An Important tool in the field topological data analysis is known as persistent Homology (PH) which is used to encode abstract representation of the homology of data at different resolutions in the form of persistence diagram (PD). In this…

Image and Video Processing · Electrical Eng. & Systems 2022-07-13 Aras Asaad , Dashti Ali , Taban Majeed , Rasber Rashid

Topology applied to real world data using persistent homology has started to find applications within machine learning, including deep learning. We present a differentiable topology layer that computes persistent homology based on level set…

Persistent homology is an important methodology in topological data analysis which adapts theory from algebraic topology to data settings. Computing persistent homology produces persistence diagrams, which have been successfully used in…

Machine Learning · Statistics 2026-01-13 Yueqi Cao , Anthea Monod

Topological data analysis (TDA) is an area of data science that focuses on using invariants from algebraic topology to provide multiscale shape descriptors for geometric data sets such as point clouds. One of the most important such…

Computational Geometry · Computer Science 2023-06-21 David Loiseaux , Mathieu Carrière , Andrew J. Blumberg

Persistent Homology (PH) has been successfully used to train networks to detect curvilinear structures and to improve the topological quality of their results. However, existing methods are very global and ignore the location of topological…

Computer Vision and Pattern Recognition · Computer Science 2022-12-27 Doruk Oner , Adélie Garin , Mateusz Koziński , Kathryn Hess , Pascal Fua

Multiparameter persistent homology is a generalization of classical persistent homology, a central and widely-used methodology from topological data analysis, which takes into account density estimation and is an effective tool for data…

Statistics Theory · Mathematics 2025-04-03 Inés García-Redondo , Anthea Monod , Qiquan Wang

Art is a deeply personal and expressive medium, where each artist brings their own style, technique, and cultural background into their work. Traditionally, identifying artistic styles has been the job of art historians or critics, relying…

Computer Vision and Pattern Recognition · Computer Science 2025-11-24 Reetikaa Reddy Munnangi , Barbara Giunti

High-quality training data is the foundation of machine learning and artificial intelligence, shaping how models learn and perform. Although much is known about what types of data are effective for training, the impact of the data's…

Machine Learning · Computer Science 2025-10-21 Yang Ba , Mohammad Sadeq Abolhasani , Rong Pan

Graph Signal Processing deals with the problem of analyzing and processing signals defined on graphs. In this paper, we introduce a novel filtering method for graph-based signals by employing ideas from topological data analysis. We begin…

Signal Processing · Electrical Eng. & Systems 2024-08-27 Matias de Jong van Lier , Sebastián Elías Graiff Zurita , Shizuo Kaji

In persistent homology analysis, interval modules play a central role in describing the birth and death of topological features across a filtration. In this work, we extend this setting, and propose the use of bipath persistent homology,…

Algebraic Topology · Mathematics 2024-04-04 Toshitaka Aoki , Emerson G. Escolar , Shunsuke Tada

Persistent homology (PH) is a method used in topological data analysis (TDA) to study qualitative features of data that persist across multiple scales. It is robust to perturbations of input data, independent of dimensions and coordinates,…

Algebraic Topology · Mathematics 2017-09-13 Nina Otter , Mason A. Porter , Ulrike Tillmann , Peter Grindrod , Heather A. Harrington

Persistent homology is a powerful mathematical tool that summarizes useful information about the shape of data allowing one to detect persistent topological features while one adjusts the resolution. However, the computation of such…

Quantum Physics · Physics 2022-03-01 Bernardo Ameneyro , Vasileios Maroulas , George Siopsis

In this paper we present a new approach to computing homology (with field coefficients) and persistent homology. We use concepts from discrete Morse theory, to provide an algorithm which can be expressed solely in terms of simple graph…

Algebraic Topology · Mathematics 2012-10-26 Paweł Dłotko , Hubert Wagner

Multiplexed imaging allows multiple cell types to be simultaneously visualised in a single tissue sample, generating unprecedented amounts of spatially-resolved, biological data. In topological data analysis, persistent homology provides…

Quantitative Methods · Quantitative Biology 2025-05-06 Maria Torras-Pérez , Iris H. R. Yoon , Praveen Weeratunga , Ling-Pei Ho , Helen M. Byrne , Ulrike Tillmann , Heather A. Harrington

Persistent homology is a technique recently developed in algebraic and computational topology well-suited to analysing structure in complex, high-dimensional data. In this paper, we exposit the theory of persistent homology from first…

Applications · Statistics 2016-11-30 Matthew Pietrosanu

Understanding the decision-making processes of large language models is critical given their widespread applications. To achieve this, we aim to connect a formal mathematical framework - zigzag persistence from topological data analysis -…

Computation and Language · Computer Science 2025-06-16 Yuri Gardinazzi , Karthik Viswanathan , Giada Panerai , Alessio Ansuini , Alberto Cazzaniga , Matteo Biagetti