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Machine Learning (ML) research has increased substantially in recent years, due to the success of predictive modeling across diverse application domains. However, well-known barriers exist when attempting to deploy ML models in high-stakes,…
Many prescriptive approaches to developing software intensive systems have been advocated but each is based on assumptions about context. It has been found that practitioners do not follow prescribed methodologies, but rather select and…
The transformative potential of artificial intelligence (AI) in medical Imaging (MI) is well recognized. Yet despite promising reports in research settings, many AI tools fail to achieve clinical adoption in practice. In fact, more…
Estimating the test performance of software AI-based medical devices under distribution shifts is crucial for evaluating the safety, efficiency, and usability prior to clinical deployment. Due to the nature of regulated medical device…
Electronic health records (EHRs) provide comprehensive patient data which could be better used to enhance informed decision-making, resource allocation, and coordinated care, thereby optimising healthcare delivery. However, in mental…
Requirements engineering plays a critical role in developing software systems. One of the most difficult tasks in this process is identifying functional requirements. A critical problem in many projects is missing requirements until late in…
Bioinformatics platforms have significantly changed clinical diagnostics by facilitating the analysis of genomic data, thereby advancing personalized medicine and improving patient care. This study examines the integration, usage patterns,…
In this paper we aim to refine the concept of grand challenges in medical image analysis, based on statistical principles from quantitative and qualitative experimental research. We identify two types of challenges based on their…
Requirement prioritization is recognized as an important decision-making activity in requirements engineering and software development. Requirement prioritization is applied to determine which requirements should be implemented and…
Clinical decisions are high-stakes and require explicit justification, making model interpretability essential for auditing deep clinical models prior to deployment. As the ecosystem of model architectures and explainability methods…
Artificial Intelligence (AI) systems for online recruitment markets have the potential to significantly enhance the efficiency and effectiveness of job placements and even promote fairness or inclusive hiring practices. Neglecting Diversity…
More and more distributed software systems are being developed and deployed today. Like other software, distributed software systems also need very strong quality assurance support. Distributed software is often very large/complex, has…
Recently, the U.S. Food and Drug Administration (FDA) released draft guidance \citep{FDA2026} signaling a paradigm shift that facilitates the use of Bayesian methodology as the primary analysis and decision framework for drug approval. The…
Leveraging the powerful generative capability of diffusion models (DMs) to build decision-making agents has achieved extensive success. However, there is still a demand for an easy-to-use and modularized open-source library that offers…
The integration of artificial intelligence [AI] into clinical trials has revolutionized the process of drug development and personalized medicine. Among these advancements, deep learning and predictive modelling have emerged as…
Considerable efforts have been made at the high school level to encourage girls to pursue software engineering careers and raise awareness about diversity within the field. Similarly, software companies have become more active in diversity…
Post-deployment monitoring of artificial intelligence (AI) systems in health care is essential to ensure their safety, quality, and sustained benefit-and to support governance decisions about which systems to update, modify, or…
Cyber-physical systems increasingly rely on distributed computing platforms where sensing, computing, actuation, and communication resources are shared by a multitude of applications. Such `cyber-physical cloud computing platforms' present…
In this chapter, we reflect on the use of Artificial Intelligence (AI) and its acceptance in clinical environments. We develop a general view of hindrances for clinical acceptance in the form of a pipeline model combining AI and clinical…
Business success of companies heavily depends on the availability and performance of their client applications. Due to modern development paradigms such as DevOps and microservice architectural styles, applications are decoupled into…