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Objective. (1) To assess whether neural tissue structure and biomechanics could predict functional loss in glaucoma; (2) To evaluate the importance of biomechanics in making such predictions. Design, Setting and Participants. We recruited…

Childhood myopia constitutes a significant global health concern. It exhibits an escalating prevalence and has the potential to evolve into severe, irreversible conditions that detrimentally impact familial well-being and create substantial…

Computer Vision and Pattern Recognition · Computer Science 2025-04-16 Mengtian Kang , Yansong Hu , Shuo Gao , Yuanyuan Liu , Hongbei Meng , Xuemeng Li , Xuhang Chen , Hubin Zhao , Jing Fu , Guohua Hu , Wei Wang , Yanning Dai , Arokia Nathan , Peter Smielewski , Ningli Wang , Shiming Li

Fundus diseases are major causes of visual impairment and blindness worldwide, especially in underdeveloped regions, where the shortage of ophthalmologists hinders timely diagnosis. AI-assisted fundus image analysis has several advantages,…

Image and Video Processing · Electrical Eng. & Systems 2024-04-24 Yong Liu , Mengtian Kang , Shuo Gao , Chi Zhang , Ying Liu , Shiming Li , Yue Qi , Arokia Nathan , Wenjun Xu , Chenyu Tang , Edoardo Occhipinti , Mayinuer Yusufu , Ningli Wang , Weiling Bai , Luigi Occhipinti

In this work, we propose a special cascade network for image segmentation, which is based on the U-Net networks as building blocks and the idea of the iterative refinement. The model was mainly applied to achieve higher recognition quality…

Computer Vision and Pattern Recognition · Computer Science 2018-11-22 Artem Sevastopolsky , Stepan Drapak , Konstantin Kiselev , Blake M. Snyder , Jeremy D. Keenan , Anastasia Georgievskaya

Relatively abundant availability of medical imaging data has provided significant support in the development and testing of Neural Network based image processing methods. Clinicians often face issues in selecting suitable image processing…

Image and Video Processing · Electrical Eng. & Systems 2021-09-10 Mayank Goswami

The performance of diagnostic Computer-Aided Design (CAD) systems for retinal diseases depends on the quality of the retinal images being screened. Thus, many studies have been developed to evaluate and assess the quality of such retinal…

Image and Video Processing · Electrical Eng. & Systems 2024-09-17 Saif Khalid , Hatem A. Rashwan , Saddam Abdulwahab , Mohamed Abdel-Nasser , Facundo Manuel Quiroga , Domenec Puig

Glaucoma is a chronic neurodegenerative condition that can lead to blindness. Early detection and curing are very important in stopping the disease from getting worse for glaucoma patients. The 2D fundus images and optical coherence…

Image and Video Processing · Electrical Eng. & Systems 2023-11-15 Wenyun Li , Chi-Man Pun

Optical Coherence Tomography (OCT) is essential for diagnosing conditions such as glaucoma, diabetic retinopathy, and age-related macular degeneration. Accurate retinal layer segmentation enables quantitative biomarkers critical for…

Image and Video Processing · Electrical Eng. & Systems 2025-09-10 S M Asiful Islam Saky , Ugyen Tshering

Diabetic retinopathy (DR) is a severe complication of diabetes that can cause permanent blindness. Timely diagnosis and treatment of DR are critical to avoid total loss of vision. Manual diagnosis is time consuming and error-prone. In this…

Image and Video Processing · Electrical Eng. & Systems 2021-10-05 Ramya Bygari , Rachita Naik , Uday Kumar P

Red-lesions, microaneurysms (MAs) and hemorrhages (HMs), are the early signs of diabetic retinopathy (DR). The automatic detection of MAs and HMs on retinal fundus images is a challenging task. Most of the existing methods detect either…

Image and Video Processing · Electrical Eng. & Systems 2025-05-02 Norah Asiri , Muhammad Hussain , Fadwa Al Adel

Deep learning based approaches to Computer Aided Diagnosis (CAD) typically pose the problem as an image classification (Normal or Abnormal) problem. These systems achieve high to very high accuracy in specific disease detection for which…

Computer Vision and Pattern Recognition · Computer Science 2020-10-06 Aniket Joshi , Gaurav Mishra , Jayanthi Sivaswamy

With the rapid development of artificial intelligence (AI) in medical image processing, deep learning in color fundus photography (CFP) analysis is also evolving. Although there are some open-source, labeled datasets of CFPs in the…

Objective: To develop an explainable multimodal large language model (MM-LLM) that (1) screens optic nerve head (ONH) OCT circle scans for quality and (2) generates structured clinical reports that include glaucoma diagnosis and sector-wise…

Accurate diagnosis of glaucoma is challenging, as early-stage changes are subtle and often lack clear structural or appearance cues. Most existing approaches rely on a single modality, such as fundus or optical coherence tomography (OCT),…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Zhiwei Wang , Yuxing Li , Meilu Zhu , Defeng He , Edmund Y. Lam

Glaucoma is a leading cause of irreversible blindness. Accurate segmentation of the optic disc (OD) and cup (OC) from fundus images is beneficial to glaucoma screening and diagnosis. Recently, convolutional neural networks demonstrate…

Computer Vision and Pattern Recognition · Computer Science 2019-02-21 Shujun Wang , Lequan Yu , Xin Yang , Chi-Wing Fu , Pheng-Ann Heng

Prognostic models aim to predict the future course of a disease or condition and are a vital component of personalized medicine. Statistical models make use of longitudinal data to capture the temporal aspect of disease progression;…

Machine Learning · Computer Science 2020-07-13 Joshua Bridge , Simon P. Harding , Yalin Zheng

Cervical glandular cell (GC) detection is a key step in computer-aided diagnosis for cervical adenocarcinomas screening. It is challenging to accurately recognize GCs in cervical smears in which squamous cells are the major. Widely existing…

Computer Vision and Pattern Recognition · Computer Science 2022-07-05 Ziquan Wei , Shenghua Cheng , Jing Cai , Shaoqun Zeng , Xiuli Liu , Zehua Wang

The diagnosis of glaucoma plays a critical role in the management and treatment of this vision-threatening disease. Glaucoma is a group of eye diseases that cause blindness by damaging the optic nerve at the back of the eye. Often called…

Image and Video Processing · Electrical Eng. & Systems 2024-10-24 Yuki Hagiwara , Octavia-Andreea Ciora , Maureen Monnet , Gino Lancho , Jeanette Miriam Lorenz

Accurate segmentation of the optic disc (OD) and cup (OC)in fundus images from different datasets is critical for glaucoma disease screening. The cross-domain discrepancy (domain shift) hinders the generalization of deep neural networks to…

Computer Vision and Pattern Recognition · Computer Science 2019-07-29 Shujun Wang , Lequan Yu , Kang Li , Xin Yang , Chi-Wing Fu , Pheng-Ann Heng

The early diagnosis and screening of glaucoma are important for patients to receive treatment in time and maintain eyesight. Nowadays, deep learning (DL) based models have been successfully used for computer-aided diagnosis (CAD) of…

Image and Video Processing · Electrical Eng. & Systems 2021-08-10 Yiming Bao , Jun Wang , Tong Li , Linyan Wang , Jianwei Xu , Juan Ye , Dahong Qian