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Automated diagnosis based on color fundus photography is essential for large-scale glaucoma screening. However, existing deep learning models are typically data-driven and lack explicit integration of retinal anatomical knowledge, which…

Computer Vision and Pattern Recognition · Computer Science 2026-04-15 Yuzhuo Zhou , Chi Liu , Sheng Shen , Zongyuan Ge , Fengshi Jing , Shiran Zhang , Yu Jiang , Anli Wang , Wenjian Liu , Feilong Yang , Tianqing Zhu , Xiaotong Han

Glaucoma is a chronic eye disease that leads to irreversible vision loss. The cup to disc ratio (CDR) plays an important role in the screening and diagnosis of glaucoma. Thus, the accurate and automatic segmentation of optic disc (OD) and…

Computer Vision and Pattern Recognition · Computer Science 2018-02-13 Huazhu Fu , Jun Cheng , Yanwu Xu , Damon Wing Kee Wong , Jiang Liu , Xiaochun Cao

Glaucoma is one of the primary causes of vision loss around the world, necessitating accurate and efficient detection methods. Traditional manual detection approaches have limitations in terms of cost, time, and subjectivity. Recent…

Image and Video Processing · Electrical Eng. & Systems 2023-11-03 Aized Amin Soofi , Fazal-e-Amin

Glaucoma causes an irreversible damage to retinal nerve fibers which results in vision loss, if undetected in early stage. Therefore, diagnosis of glaucoma in its early stage may prevent further vision loss. In this paper, we propose a…

Signal Processing · Electrical Eng. & Systems 2020-09-15 Shishir Maheshwari , Vivek Kanhangad , Ram Bilas Pachori

The analysis of fundus images is critical for the early detection and diagnosis of retinal diseases such as Diabetic Retinopathy (DR), Glaucoma, and Age-related Macular Degeneration (AMD). Traditional diagnostic workflows, however, often…

Computer Vision and Pattern Recognition · Computer Science 2025-07-31 Faisal Ahmed

One of the leading causes of blindness is glaucoma, which is challenging to detect since it remains asymptomatic until the symptoms are severe. Thus, diagnosis is usually possible until the markers are easy to identify, i.e., the damage has…

Image and Video Processing · Electrical Eng. & Systems 2021-10-05 Sayan Mandal , Alessandro A. Jammal , Felipe A. Medeiros

Precis: A hybrid deep-learning model combines NFL reflectance and other OCT parameters to improve glaucoma diagnosis. Objective: To investigate if a deep learning model could be used to combine nerve fiber layer (NFL) reflectance and other…

Image and Video Processing · Electrical Eng. & Systems 2024-06-07 Ou Tan , David S. Greenfield , Brian A. Francis , Rohit Varma , Joel S. Schuman , David Huang , Dongseok Choi

Glaucoma is a chronic eye disease that leads to irreversible vision loss. Most of the existing automatic screening methods firstly segment the main structure, and subsequently calculate the clinical measurement for detection and screening…

Computer Vision and Pattern Recognition · Computer Science 2018-05-22 Huazhu Fu , Jun Cheng , Yanwu Xu , Changqing Zhang , Damon Wing Kee Wong , Jiang Liu , Xiaochun Cao

Purpose: To develop a deep learning approach to digitally-stain optical coherence tomography (OCT) images of the optic nerve head (ONH). Methods: A horizontal B-scan was acquired through the center of the ONH using OCT (Spectralis) for 1…

Objective: Glaucoma is the second leading cause of blindness worldwide. Glaucomatous progression can be easily monitored by analyzing the degeneration of retinal ganglion cells (RGCs). Many researchers have screened glaucoma by measuring…

Image and Video Processing · Electrical Eng. & Systems 2020-11-22 Hina Raja , Taimur Hassan , Muhammad Usman Akram , Naoufel Werghi

Glaucoma is one of the most severe eye diseases, characterized by rapid progression and leading to irreversible blindness. It is often the case that diagnostics is carried out when one's sight has already significantly degraded due to the…

Image and Video Processing · Electrical Eng. & Systems 2022-08-02 Ahmed Al Mahrooqi , Dmitrii Medvedev , Rand Muhtaseb , Mohammad Yaqub

Early identification of patients at risk of cardiovascular diseases (CVD) is crucial for effective preventive care, reducing healthcare burden, and improving patients' quality of life. This study demonstrates the potential of retinal…

Image and Video Processing · Electrical Eng. & Systems 2024-10-21 Cynthia Maldonado-Garcia , Arezoo Zakeri , Alejandro F Frangi , Nishant Ravikumar

Ocular pathology detection from fundus images presents an important challenge on health care. In fact, each pathology has different severity stages that may be deduced by verifying the existence of specific lesions. Each lesion is…

Image and Video Processing · Electrical Eng. & Systems 2019-05-08 Yaroub Elloumi , Mohamed Akil , Henda Boudegga

Taking into account that glaucoma is the leading cause of blindness worldwide, we propose in this paper three different learning methodologies for glaucoma detection in order to elucidate that traditional machine-learning techniques could…

Image and Video Processing · Electrical Eng. & Systems 2020-09-10 Gabriel García , Adrián Colomer , Valery Naranjo

Glaucoma is a disease in which the optic nerve is chronically damaged by the elevation of the intra-ocular pressure, resulting in visual field defect. Therefore, it is important to monitor and treat suspected patients before they are…

Computer Vision and Pattern Recognition · Computer Science 2018-07-05 Tae Joon Jun , Dohyeun Kim , Hoang Minh Nguyen , Daeyoung Kim , Youngsub Eom

We describe a new approach to automated Glaucoma detection in 3D Spectral Domain Optical Coherence Tomography (OCT) optic nerve scans. First, we gathered a unique and diverse multi-ethnic dataset of OCT scans consisting of glaucoma and…

With the advancements in medical artificial intelligence (AI), fundus image classifiers are increasingly being applied to assist in ophthalmic diagnosis. While existing classification models have achieved high accuracy on specific fundus…

Computer Vision and Pattern Recognition · Computer Science 2025-04-02 Yuzhuo Zhou , Chi Liu , Sheng Shen , Siyu Le , Liwen Yu , Sihan Ouyang , Zongyuan Ge

Automated segmentation of the optic cup and disk on retinal fundus images is fundamental for the automated detection / analysis of glaucoma. Traditional segmentation approaches depend heavily upon hand-crafted features and a priori…

Computer Vision and Pattern Recognition · Computer Science 2019-02-14 Lei Bi , Yuyu Guo , Qian Wang , Dagan Feng , Michael Fulham , Jinman Kim

Background/Aims: Standard Automated Perimetry (SAP) is the gold standard to monitor visual field (VF) loss in glaucoma management, but is prone to intra-subject variability. We developed and validated a deep learning (DL) regression model…

Image and Video Processing · Electrical Eng. & Systems 2021-06-08 Ruben Hemelings , Bart Elen , João Barbosa Breda , Erwin Bellon , Matthew B Blaschko , Patrick De Boever , Ingeborg Stalmans

With the advancement of deep learning techniques, an increasing number of methods have been proposed for optic disc and cup (OD/OC) segmentation from the fundus images. Clinically, OD/OC segmentation is often annotated by multiple clinical…

Image and Video Processing · Electrical Eng. & Systems 2022-09-20 Junde Wu , Huihui Fang , Dalu Yang , Zhaowei Wang , Wenshuo Zhou , Fangxin Shang , Yehui Yang , Yanwu Xu