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Selecting the right compiler optimisations has a severe impact on programs' performance. Still, the available optimisations keep increasing, and their effect depends on the specific program, making the task human intractable. Researchers…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-05-12 Stefano Cereda , Gianluca Palermo , Paolo Cremonesi , Stefano Doni

The task of RNA design given a target structure aims to find a sequence that can fold into that structure. It is a computationally hard problem where some version(s) have been proven to be NP-hard. As a result, heuristic methods such as…

Biomolecules · Quantitative Biology 2024-12-13 Wei Yu Tang , Ning Dai , Tianshuo Zhou , David H. Mathews , Liang Huang

This paper reviews recent advances in big data optimization, providing the state-of-art of this emerging field. The main focus in this review are optimization techniques being applied in big data analysis environments. Integer linear…

Neural and Evolutionary Computing · Computer Science 2021-02-04 Ricardo Di Pasquale , Javier Marenco

We formulate the search for phenomenological models of synaptic plasticity as an optimization problem. We employ Cartesian genetic programming to evolve biologically plausible human-interpretable plasticity rules that allow a given network…

Neural and Evolutionary Computing · Computer Science 2021-02-09 Henrik D. Mettler , Maximilian Schmidt , Walter Senn , Mihai A. Petrovici , Jakob Jordan

Bilevel optimization is defined as a mathematical program, where an optimization problem contains another optimization problem as a constraint. These problems have received significant attention from the mathematical programming community.…

Optimization and Control · Mathematics 2020-12-08 Ankur Sinha , Pekka Malo , Kalyanmoy Deb

The development and identification of effective optimization algorithms for non-convex real-world problems is a challenge in global optimization. Because theoretical performance analysis is difficult, and problems based on models of…

Optimization and Control · Mathematics 2018-07-16 Ramses Sala , Niccolò Baldanzini , Marco Pierini

Evolutionary algorithms have been widely applied for solving dynamic constrained optimization problems (DCOPs) as a common area of research in evolutionary optimization. Current benchmarks proposed for testing these problems in the…

Neural and Evolutionary Computing · Computer Science 2019-07-10 Maryam Hasani-Shoreh , María-Yaneli Ameca-Alducin , Wilson Blaikie , Frank Neumann , Marc Schoenauer

We propose that genetic encoding of self-assembling components greatly enhances the evolution of complex systems and provides an efficient platform for inductive generalization, i.e. the inductive derivation of a solution to a problem with…

Populations and Evolution · Quantitative Biology 2007-05-23 Rudolf M. Fuechslin , Thomas Maeke , Uwe Tangen , John S. McCaskill

Machine Learning algorithms have been extensively researched throughout the last decade, leading to unprecedented advances in a broad range of applications, such as image classification and reconstruction, object recognition, and text…

Artificial Intelligence · Computer Science 2022-12-20 Gustavo H. de Rosa , Mateus Roder , João Paulo Papa , Claudio F. G. dos Santos

In the real world, there exist a class of optimization problems that multiple (local) optimal solutions in the solution space correspond to a single point in the objective space. In this paper, we theoretically show that for such multimodal…

Neural and Evolutionary Computing · Computer Science 2024-06-06 Shengjie Ren , Zhijia Qiu , Chao Bian , Miqing Li , Chao Qian

The mathematical runtime analysis of evolutionary algorithms traditionally regards the time an algorithm needs to find a solution of a certain quality when initialized with a random population. In practical applications it may be possible…

Neural and Evolutionary Computing · Computer Science 2025-11-14 Denis Antipov , Maxim Buzdalov , Benjamin Doerr

The ultimate goal of all optimization methods is to solve real-world problems. For a successful project execution, knowledge about optimization and the application has to be pooled. As it is too inefficient to highly train one person in…

Optimization and Control · Mathematics 2016-07-19 Simon Wessing

Single-objective bilevel optimization is a specialized form of constraint optimization problems where one of the constraints is an optimization problem itself. These problems are typically non-convex and strongly NP-Hard. Recently, there…

Neural and Evolutionary Computing · Computer Science 2024-02-13 Anuraganand Sharma

A random-key genetic algorithm is an evolutionary metaheuristic for discrete and global optimization. Each solution is encoded as a vector of N random keys, where a random key is a real number randomly generated in the continuous interval…

Neural and Evolutionary Computing · Computer Science 2026-01-13 Mariana A. Londe , Luciana S. Pessoa , Carlos E. Andrade , José F. Gonçalves , Mauricio G. C. Resende

Challenges in natural sciences can often be phrased as optimization problems. Machine learning techniques have recently been applied to solve such problems. One example in chemistry is the design of tailor-made organic materials and…

Neural and Evolutionary Computing · Computer Science 2020-01-17 AkshatKumar Nigam , Pascal Friederich , Mario Krenn , Alán Aspuru-Guzik

As the demand for computational power grows, optimizing code through compilers becomes increasingly crucial. In this context, we focus on fully automatic code optimization techniques that automate the process of selecting and applying code…

Programming Languages · Computer Science 2025-11-11 Yacine Hakimi , Riyadh Baghdadi

The concept of extended cloud requires efficient network infrastructure to support ecosystems reaching form the edge to the cloud(s). Standard approaches to network load balancing deliver static solutions that are insufficient for the…

Networking and Internet Architecture · Computer Science 2023-07-20 Marek Bolanowski , Alicja Gerka , Andrzej Paszkiewicz , Maria Ganzha , Marcin Paprzycki

Optimization aims at selecting a feasible set of parameters in an attempt to solve a particular problem, being applied in a wide range of applications, such as operations research, machine learning fine-tuning, and control engineering,…

Neural and Evolutionary Computing · Computer Science 2020-12-03 Gustavo H. de Rosa , Douglas Rodrigues , João P. Papa

Optimization is a ubiquitous modeling tool and is often deployed in settings which repeatedly solve similar instances of the same problem. Amortized optimization methods use learning to predict the solutions to problems in these settings,…

Machine Learning · Computer Science 2025-10-07 Brandon Amos

Research on new optimization algorithms is often funded based on the motivation that such algorithms might improve the capabilities to deal with real-world and industrially relevant optimization challenges. Besides a huge variety of…

Neural and Evolutionary Computing · Computer Science 2020-07-02 Ramses Sala , Ralf Müller