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Analyzing and predicting brain aging is essential for early prognosis and accurate diagnosis of cognitive diseases. The technique of neuroimaging, such as Magnetic Resonance Imaging (MRI), provides a noninvasive means of observing the aging…

Image and Video Processing · Electrical Eng. & Systems 2022-12-06 Jingru Fu , Antonios Tzortzakakis , José Barroso , Eric Westman , Daniel Ferreira , Rodrigo Moreno

Purpose: To develop an age prediction model which is interpretable and robust to demographic and technological variances in brain MRI scans. Materials and Methods: We propose a transformer-based architecture that leverages self-supervised…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Pengyu Kan , Craig Jones , Kenichi Oishi

In recent years, deep convolutional neural networks (CNNs) have shown record-shattering performance in a variety of computer vision problems, such as visual object recognition, detection and segmentation. These methods have also been…

Computer Vision and Pattern Recognition · Computer Science 2019-07-30 Jose Bernal , Kaisar Kushibar , Daniel S. Asfaw , Sergi Valverde , Arnau Oliver , Robert Martí , Xavier Lladó

Brain age is the estimate of biological age derived from neuroimaging datasets using machine learning algorithms. Increasing \textit{brain age gap} characterized by an elevated brain age relative to the chronological age can reflect…

Machine Learning · Computer Science 2025-01-06 Saurabh Sihag , Gonzalo Mateos , Alejandro Ribeiro

We propose an interpretable 3D Grid-Attention deep neural network that can accurately predict a person's age and whether they have Alzheimer's disease (AD) from a structural brain MRI scan. Building on a 3D convolutional neural network, we…

Tissues and Organs · Quantitative Biology 2020-11-19 Pradeep Lam , Alyssa H. Zhu , Iyad Ba Gari , Neda Jahanshad , Paul M. Thompson

Brain extraction or whole brain segmentation is an important first step in many of the neuroimage analysis pipelines. The accuracy and robustness of brain extraction, therefore, is crucial for the accuracy of the entire brain analysis…

Computer Vision and Pattern Recognition · Computer Science 2017-06-21 Seyed Sadegh Mohseni Salehi , Deniz Erdogmus , Ali Gholipour

Brain age prediction using neuroimaging data has shown great potential as an indicator of overall brain health and successful aging, as well as a disease biomarker. Deep learning models have been established as reliable and efficient brain…

Computer Vision and Pattern Recognition · Computer Science 2023-10-24 Bruno Machado Pacheco , Victor Hugo Rocha de Oliveira , Augusto Braga Fernandes Antunes , Saulo Domingos de Souza Pedro , Danilo Silva

Brain age estimation based on magnetic resonance imaging (MRI) is an active research area in early diagnosis of some neurodegenerative diseases (e.g. Alzheimer, Parkinson, Huntington, etc.) for elderly people or brain underdevelopment for…

Image and Video Processing · Electrical Eng. & Systems 2021-08-04 Ruizhe Li , Matteo Bastiani , Dorothee Auer , Christian Wagner , Xin Chen

This paper is a part of a student project in Machine Learning at the Norwegian University of Science and Technology. In this paper, a deep convolutional neural network with five convolutional layers and three fully-connected layers is…

Computer Vision and Pattern Recognition · Computer Science 2021-05-17 Adrian Kjærran , Christian Bakke Vennerød , Erling Stray Bugge

The brain age has been proven to be a phenotype of relevance to cognitive performance and brain disease. Achieving accurate brain age prediction is an essential prerequisite for optimizing the predicted brain-age difference as a biomarker.…

Image and Video Processing · Electrical Eng. & Systems 2022-09-20 Yanwu Yang , Xutao Guo , Zhikai Chang , Chenfei Ye , Yang Xiang , Haiyan Lv , Ting Ma

The accurate identification of brain tumors from magnetic resonance imaging (MRI) is essential for timely diagnosis and effective therapeutic intervention. While deep convolutional neural networks (CNNs), particularly those pre-trained on…

Computer Vision and Pattern Recognition · Computer Science 2026-03-02 Helia Abedini , Saba Rahimi , Reza Vaziri

Accurate estimation of biological brain age from three dimensional (3D) T$_1$-weighted magnetic resonance imaging (MRI) is a critical imaging biomarker for identifying accelerated aging associated with neurodegenerative diseases. Effective…

Image and Video Processing · Electrical Eng. & Systems 2025-08-05 Mehreen Kanwal , Yunsik Son

Predicting brain maturity using noninvasive magnetic resonance images (MRI) can distinguish different age groups and help to assess neurodevelopmental disorders. However, group-wise differences are often less informative for assessing…

Neurons and Cognition · Quantitative Biology 2014-12-17 Cheol E. Han , Luis R. Peraza , John-Paul Taylor , Marcus Kaiser

Early detection is a crucial goal in the study of Alzheimer's Disease (AD). In this work, we describe several techniques to boost the performance of 3D deep convolutional neural networks (CNNs) trained to detect AD using structural brain…

Image and Video Processing · Electrical Eng. & Systems 2020-04-07 Sheng Liu , Chhavi Yadav , Carlos Fernandez-Granda , Narges Razavian

Neuroimaging-driven prediction of brain age, defined as the predicted biological age of a subject using only brain imaging data, is an exciting avenue of research. In this work we seek to build models of brain age based on functional…

Purpose: The purpose of this study was to observe change in accuracies of convolutional neural networks (CNN) models (ratio of correct classifications to total predictions) on thoracic radiological images by creating different binary…

Image and Video Processing · Electrical Eng. & Systems 2019-12-03 Mir Muhammad Abdullah , Mir Muhammad Abdur Rahman , Mir Mohammed Assadullah

The brain tumor is the most aggressive kind of tumor and can cause low life expectancy if diagnosed at the later stages. Manual identification of brain tumors is tedious and prone to errors. Misdiagnosis can lead to false treatment and thus…

Image and Video Processing · Electrical Eng. & Systems 2022-08-02 Dmytro Filatov , Ghulam Nabi Ahmad Hassan Yar

Deep Learning (DL) and specifically CNN models have become a de facto method for a wide range of vision tasks, outperforming traditional machine learning (ML) methods. Consequently, they drew a lot of attention in the neuroimaging field in…

Computer Vision and Pattern Recognition · Computer Science 2023-04-18 Benoit Dufumier , Pietro Gori , Ilaria Battaglia , Julie Victor , Antoine Grigis , Edouard Duchesnay

Convolutional neural networks (CNN) for medical imaging are constrained by the number of annotated data required in the training stage. Usually, manual annotation is considered to be the "gold standard". However, medical imaging datasets…

Computer Vision and Pattern Recognition · Computer Science 2018-04-16 Oeslle Lucena , Roberto Souza , Leticia Rittner , Richard Frayne , Roberto Lotufo

Neurodegeneration, characterized by the progressive loss of neuronal structure or function, is commonly assessed in clinical practice through reductions in cortical thickness or brain volume, as visualized by structural MRI. While…

Signal Processing · Electrical Eng. & Systems 2025-10-15 Saurabh Sihag , Gonzalo Mateos , Alejandro Ribeiro