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Protein secondary structure prediction is an important problem in bioinformatics. Inspired by the recent successes of deep neural networks, in this paper, we propose an end-to-end deep network that predicts protein secondary structures from…

Biomolecules · Quantitative Biology 2016-04-27 Zhen Li , Yizhou Yu

Predicting protein interactions is one of the more interesting challenges of the post-genomic era. Many algorithms address this problem as a binary classification problem: given two proteins represented as two vectors of features, predict…

Molecular Networks · Quantitative Biology 2011-11-01 Ossnat Bar-Shira , Gal Chechik

This paper investigates the usage of kernel functions at the different layers in a convolutional neural network. We carry out extensive studies of their impact on convolutional, pooling and fully-connected layers. We notice that the linear…

Computer Vision and Pattern Recognition · Computer Science 2023-02-22 M. Amine Mahmoudi , Aladine Chetouani , Fatma Boufera , Hedi Tabia

Protein-RNA interactions are of vital importance to a variety of cellular activities. Both experimental and computational techniques have been developed to study the interactions. Due to the limitation of the previous database, especially…

Biomolecules · Quantitative Biology 2021-11-24 Junkang Wei , Siyuan Chen , Licheng Zong , Xin Gao , Yu Li

Automatic segmentation of lung lesions associated with COVID-19 in CT images requires large amount of annotated volumes. Annotations mandate expert knowledge and are time-intensive to obtain through fully manual segmentation methods.…

Image and Video Processing · Electrical Eng. & Systems 2023-09-06 Muhammad Asad , Lucas Fidon , Tom Vercauteren

Recently, Miller et al. showed that a model's in-distribution (ID) accuracy has a strong linear correlation with its out-of-distribution (OOD) accuracy on several OOD benchmarks -- a phenomenon they dubbed ''accuracy-on-the-line''. While a…

Machine Learning · Computer Science 2023-05-12 Christina Baek , Yiding Jiang , Aditi Raghunathan , Zico Kolter

We present a novel approach to neural response prediction that incorporates higher-order operations directly within convolutional neural networks (CNNs). Our model extends traditional 3D CNNs by embedding higher-order operations within the…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Simone Azeglio , Victor Calbiague Garcia , Guilhem Glaziou , Peter Neri , Olivier Marre , Ulisse Ferrari

As high-throughput biological sequencing becomes faster and cheaper, the need to extract useful information from sequencing becomes ever more paramount, often limited by low-throughput experimental characterizations. For proteins, accurate…

Quantitative Methods · Quantitative Biology 2017-01-31 Xueliang Liu

Contour information plays a vital role in salient object detection. However, excessive false positives remain in predictions from existing contour-based models due to insufficient contour-saliency fusion. In this work, we designed a network…

Computer Vision and Pattern Recognition · Computer Science 2021-08-24 Yi Ke Yun , Takahiro Tsubono

Over the past few years, deep neural networks (DNNs) have exhibited great success in predicting the saliency of images. However, there are few works that apply DNNs to predict the saliency of generic videos. In this paper, we propose a…

Computer Vision and Pattern Recognition · Computer Science 2019-01-16 Lai Jiang , Mai Xu , Zulin Wang

User response prediction is a crucial component for personalized information retrieval and filtering scenarios, such as recommender system and web search. The data in user response prediction is mostly in a multi-field categorical format…

Information Retrieval · Computer Science 2018-07-03 Yanru Qu , Bohui Fang , Weinan Zhang , Ruiming Tang , Minzhe Niu , Huifeng Guo , Yong Yu , Xiuqiang He

Over the past few years, state-of-the-art image segmentation algorithms are based on deep convolutional neural networks. To render a deep network with the ability to understand a concept, humans need to collect a large amount of pixel-level…

Computer Vision and Pattern Recognition · Computer Science 2020-03-25 Weide Liu , Chi Zhang , Guosheng Lin , Fayao Liu

The graph neural network (GNN) has been a powerful deep-learning tool in chemistry domain, due to its close connection with molecular graphs. Most GNN models collect and update atom and molecule features from the fed atom (and, in some…

Chemical Physics · Physics 2022-03-18 Yeji Kim , Yoonho Jeong , Jihoo Kim , Eok Kyun Lee , Won June Kim , Insung S. Choi

Deep neural network has been ensured as a key technology in the field of many challenging and vigorously researched computer vision tasks. Furthermore, classical ResNet is thought to be a state-of-the-art convolutional neural network (CNN)…

Computer Vision and Pattern Recognition · Computer Science 2024-09-02 Prathibha Varghese , G. Arockia Selva Saroja

Graph neural networks (GNN) have been shown to provide substantial performance improvements for atomistic material representation and modeling compared with descriptor-based machine learning models. While most existing GNN models for…

Materials Science · Physics 2022-04-08 Kamal Choudhary , Brian DeCost

Porting state of the art deep learning algorithms to resource constrained compute platforms (e.g. VR, AR, wearables) is extremely challenging. We propose a fast, compact, and accurate model for convolutional neural networks that enables…

Computer Vision and Pattern Recognition · Computer Science 2017-06-14 Hessam Bagherinezhad , Mohammad Rastegari , Ali Farhadi

Background: One-dimensional protein structures such as secondary structures or contact numbers are useful for three-dimensional structure prediction and helpful for intuitive understanding of the sequence-structure relationship. Accurate…

Biomolecules · Quantitative Biology 2007-07-09 Akira R. Kinjo , Ken Nishikawa

In this paper, we propose a new deep framework which predicts facial attributes and leverage it as a soft modality to improve face identification performance. Our model is an end to end framework which consists of a convolutional neural…

Computer Vision and Pattern Recognition · Computer Science 2018-05-02 Fariborz Taherkhani , Nasser M. Nasrabadi , Jeremy Dawson

Recently, relying on convolutional neural networks (CNNs), many methods for salient object detection in optical remote sensing images (ORSI-SOD) are proposed. However, most methods ignore the huge parameters and computational cost brought…

Computer Vision and Pattern Recognition · Computer Science 2023-04-04 Gongyang Li , Zhi Liu , Xinpeng Zhang , Weisi Lin

Predicting the docking between proteins and ligands is a crucial and challenging task for drug discovery. However, traditional docking methods mainly rely on scoring functions, and deep learning-based docking approaches usually neglect the…

Biomolecules · Quantitative Biology 2026-01-06 Yiqiang Yi , Xu Wan , Yatao Bian , Le Ou-Yang , Peilin Zhao