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Machine learning is widely used in developing computer-aided diagnosis (CAD) schemes of medical images. However, CAD usually computes large number of image features from the targeted regions, which creates a challenge of how to identify a…

Computer Vision and Pattern Recognition · Computer Science 2021-02-09 Morteza Heidari , Sivaramakrishnan Lakshmivarahan , Seyedehnafiseh Mirniaharikandehei , Gopichandh Danala , Sai Kiran R. Maryada , Hong Liu , Bin Zheng

When faced with the problem of learning a model of a high-dimensional environment, a common approach is to limit the model to make only a restricted set of predictions, thereby simplifying the learning problem. These partial models may be…

Machine Learning · Computer Science 2014-01-17 Erik Talvitie , Satinder Singh

Developing spatio-temporal crime prediction models, and to a lesser extent, developing measures of accuracy and operational efficiency for them, has been an active area of research for almost two decades. Despite calls for rigorous and…

Applications · Statistics 2020-06-16 Chaitanya Joshi , Clayton D'Ath , Sophie Curtis-Ham , Deane Searle

Gliomas, the most prevalent primary brain tumors, require precise segmentation for diagnosis and treatment planning. However, this task poses significant challenges, particularly in the African population, were limited access to…

Image and Video Processing · Electrical Eng. & Systems 2023-12-20 Mohannad Barakat , Noha Magdy , Jjuuko George William , Ethel Phiri , Raymond Confidence , Dong Zhang , Udunna C Anazodo

Deep learning has quickly become the weapon of choice for brain lesion segmentation. However, few existing algorithms pre-configure any biological context of their chosen segmentation tissues, and instead rely on the neural network's…

Computer Vision and Pattern Recognition · Computer Science 2017-09-12 Andrew Beers , Ken Chang , James Brown , Emmett Sartor , CP Mammen , Elizabeth Gerstner , Bruce Rosen , Jayashree Kalpathy-Cramer

The majority of cancer treatments end in failure due to Intra-Tumor Heterogeneity (ITH). ITH in cancer is represented by clonal evolution where different sub-clones compete with each other for resources under conditions of Darwinian natural…

Brain tumors result from abnormal cell growth in brain tissue. If undiagnosed, they cause neurological deficits, including cognitive impairment, motor dysfunction, and sensory loss. As tumors grow, intracranial pressure increases,…

Image and Video Processing · Electrical Eng. & Systems 2025-03-19 Shravan Venkatraman , Pandiyaraju V , Abeshek A , Aravintakshan S A , Pavan Kumar S , Kannan A , Madhan S

We present a framework to train a structured prediction model by performing smoothing on the inference algorithm it builds upon. Smoothing overcomes the non-smoothness inherent to the maximum margin structured prediction objective, and…

Machine Learning · Statistics 2019-02-11 Krishna Pillutla , Vincent Roulet , Sham M. Kakade , Zaid Harchaoui

In this paper, we use the Bayesian inversion approach to study the data assimilation problem for a family of tumor growth models described by porous-medium type equations. The models contain uncertain parameters and are indexed by a…

Numerical Analysis · Mathematics 2024-02-14 Yu Feng , Liu Liu , Zhennan Zhou

Gliomas are the most common malignant primary brain tumors in adults and one of the deadliest types of cancer. There are many challenges in treatment and monitoring due to the genetic diversity and high intrinsic heterogeneity in…

Computer Vision and Pattern Recognition · Computer Science 2024-05-29 Maria Correia de Verdier , Rachit Saluja , Louis Gagnon , Dominic LaBella , Ujjwall Baid , Nourel Hoda Tahon , Martha Foltyn-Dumitru , Jikai Zhang , Maram Alafif , Saif Baig , Ken Chang , Gennaro D'Anna , Lisa Deptula , Diviya Gupta , Muhammad Ammar Haider , Ali Hussain , Michael Iv , Marinos Kontzialis , Paul Manning , Farzan Moodi , Teresa Nunes , Aaron Simon , Nico Sollmann , David Vu , Maruf Adewole , Jake Albrecht , Udunna Anazodo , Rongrong Chai , Verena Chung , Shahriar Faghani , Keyvan Farahani , Anahita Fathi Kazerooni , Eugenio Iglesias , Florian Kofler , Hongwei Li , Marius George Linguraru , Bjoern Menze , Ahmed W. Moawad , Yury Velichko , Benedikt Wiestler , Talissa Altes , Patil Basavasagar , Martin Bendszus , Gianluca Brugnara , Jaeyoung Cho , Yaseen Dhemesh , Brandon K. K. Fields , Filip Garrett , Jaime Gass , Lubomir Hadjiiski , Jona Hattangadi-Gluth , Christopher Hess , Jessica L. Houk , Edvin Isufi , Lester J. Layfield , George Mastorakos , John Mongan , Pierre Nedelec , Uyen Nguyen , Sebastian Oliva , Matthew W. Pease , Aditya Rastogi , Jason Sinclair , Robert X. Smith , Leo P. Sugrue , Jonathan Thacker , Igor Vidic , Javier Villanueva-Meyer , Nathan S. White , Mariam Aboian , Gian Marco Conte , Anders Dale , Mert R. Sabuncu , Tyler M. Seibert , Brent Weinberg , Aly Abayazeed , Raymond Huang , Sevcan Turk , Andreas M. Rauschecker , Nikdokht Farid , Philipp Vollmuth , Ayman Nada , Spyridon Bakas , Evan Calabrese , Jeffrey D. Rudie

As geospatial machine learning models and maps derived from their predictions are increasingly used for downstream analyses in science and policy, it is imperative to evaluate their accuracy and applicability. Geospatial machine learning…

Machine Learning · Computer Science 2023-04-03 Esther Rolf

Intra-tumor heterogeneity driving disease progression is characterized by distinct growth and spatial proliferation patterns of cells and their nuclei within tumor and non-tumor tissues. A widely accepted hypothesis is that these spatial…

Applications · Statistics 2025-11-13 Ye Jin Choi , Sebastian Kurtek , Simeng Zhu , Karthik Bharath

The present paper deals with a free boundary problem modeling the growth process of necrotic multi-layer tumors. We prove the existence of flat stationary solutions and determine the linearization of our model at such an equilibrium.…

Analysis of PDEs · Mathematics 2012-09-18 Martin Kohlmann

Accurate characterization of glioma is crucial for clinical decision making. A delineation of the tumor is also desirable in the initial decision stages but is a time-consuming task. Leveraging the latest GPU capabilities, we developed a…

In this article we shall trace the historical development of tumour growth laws, which in a quantitative fashion describe the increase in tumour mass/volume over time. These models are usually formulated in terms of differential equations…

Tissues and Organs · Quantitative Biology 2013-02-11 P. Gerlee

Farmers frequently assess plant growth and performance as basis for making decisions when to take action in the field, such as fertilization, weed control, or harvesting. The prediction of plant growth is a major challenge, as it is…

Computer Vision and Pattern Recognition · Computer Science 2023-12-07 Lukas Drees , Laura Verena Junker-Frohn , Jana Kierdorf , Ribana Roscher

Genomics are rapidly transforming medical practice and basic biomedical research, providing insights into disease mechanisms and improving therapeutic strategies, particularly in cancer. The ability to predict the future course of a…

Neural and Evolutionary Computing · Computer Science 2016-09-29 Safoora Yousefi , Congzheng Song , Nelson Nauata , Lee Cooper

The next generation of weak lensing surveys will trace the growth of large scale perturbations through a sequence of epochs, offering an opportunity to test General Relativity (GR) on cosmological scales. We review in detail the…

Cosmology and Nongalactic Astrophysics · Physics 2011-06-14 Levon Pogosian , Alessandra Silvestri , Kazuya Koyama , Gong-Bo Zhao

Many important multiple-objective decision problems can be cast within the framework of ranking under constraints and solved via a weighted bipartite matching linear program. Some of these optimization problems, such as personalized content…

Information Retrieval · Computer Science 2022-02-16 Yegor Tkachenko , Wassim Dhaouadi , Kamel Jedidi

We consider four main goals when fitting spatial linear models: 1) estimating covariance parameters, 2) estimating fixed effects, 3) kriging (making point predictions), and 4) block-kriging (predicting the average value over a region). Each…

Methodology · Statistics 2023-05-16 Jay M. Ver Hoef , Michael Dumelle , Matt Higham , Erin E. Peterson , Daniel J. Isaak