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Medical differential phase contrast x-ray imaging (DPCI) promises improved soft-tissue contrast at lower x-ray dose. The dose strongly depends on both the angular sensitivity and on the visibility of a grating-based Talbot-Lau…

Medical Physics · Physics 2016-03-23 Oliver Preusche

X-Ray Phase-Contrast Imaging (PCI) yields absorption, differential phase, and dark-field images. Computed Tomography (CT) of grating-based PCI can in principle provide high-resolution soft-tissue contrast. Recently, grating-based PCI took…

We study Bayesian inverse problems with mixed noise, modeled as a combination of additive and multiplicative Gaussian components. While traditional inference methods often assume fixed or known noise characteristics, real-world…

Machine Learning · Computer Science 2025-10-17 Paul Hagemann , Robert Gruhlke , Bernhard Stankewitz , Claudia Schillings , Gabriele Steidl

X-ray phase contrast imaging (XPCI) provides higher sensitivity to contrast between low absorbing objects that can be invisible to conventional attenuation-based X-ray imaging. XPCI's main application has been so far focused on medical…

The diffraction contrast modalities accessible by X-ray grating interferometers are not imaged directly but have to be inferred from sine like signal variations occurring in a series of images acquired at varying relative positions of the…

Instrumentation and Detectors · Physics 2021-02-01 Jonas Dittmann , Andreas Balles , Simon Zabler

The performance of flow matching and diffusion models can be greatly improved at inference time using reward alignment algorithms, yet efficiency remains a major limitation. While several algorithms were proposed, we demonstrate that a…

Machine Learning · Computer Science 2026-02-12 Peter Holderrieth , Uriel Singer , Tommi Jaakkola , Ricky T. Q. Chen , Yaron Lipman , Brian Karrer

X-ray phase-contrast imaging (XPCI) is a versatile technique with wide-ranging applications, particularly in the fields of biology and medicine. Where X-ray absorption radiography requires high density ratios for effective imaging, XPCI is…

Black-box variational inference (BBVI) with Gaussian mixture families offers a flexible approach for approximating complex posterior distributions without requiring gradients of the target density. However, standard numerical optimization…

Machine Learning · Computer Science 2026-05-29 Baojun Che , Yifan Chen , Daniel Zhengyu Huang , Xinying Mao , Weijie Wang

Diffusion and flow-based generative models have shown strong potential for image restoration. However, image denoising under unknown and varying noise conditions remains challenging, because the learned vector fields may become inconsistent…

Computer Vision and Pattern Recognition · Computer Science 2026-04-06 Jigang Duan , Genwei Ma , Xu Jiang , Wenfeng Xu , Ping Yang , Xing Zhao

Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is essential for breast cancer diagnosis due to its ability to characterize tissue through contrast agent kinetics. However, traditional DCE-MRI protocols require multiple…

Computer Vision and Pattern Recognition · Computer Science 2025-01-28 Ruben D. Fonnegra , Maria Liliana Hernández , Juan C. Caicedo , Gloria M. Díaz

Event cameras have recently gained significant traction since they open up new avenues for low-latency and low-power solutions to complex computer vision problems. To unlock these solutions, it is necessary to develop algorithms that can…

Computer Vision and Pattern Recognition · Computer Science 2023-09-28 Federico Paredes-Vallés , Kirk Y. W. Scheper , Christophe De Wagter , Guido C. H. E. de Croon

Text-to-image (T2I) diffusion models have demonstrated impressive performance in generating high-fidelity images, largely enabled by text-guided inference. However, this advantage often comes with a critical drawback: limited diversity, as…

Graphics · Computer Science 2026-03-17 Byungjun Kim , Soobin Um , Jong Chul Ye

X-ray phase-contrast imaging has experienced rapid development over the last few decades, and in this technology, the phase modulation strategy of phase-stepping is used most widely to measure the sample's phase signal. However, because of…

Medical Physics · Physics 2017-12-06 Faiz Wali , Shenghao Wang , Huajie Han , Kun Gao , Zhao Wu , Peiping Zhu , Yangchao Tiana

In the hard X rays domain, the phase shift of the wave passing through the soft materials like tissues is typically three orders of magnitude larger than the absorption. Therefore the phase-sensitive X-ray imaging methods can obtain…

Instrumentation and Detectors · Physics 2018-06-12 Lian Chen , Rongqi Sun , Ge Jin

Deep learning (DL) based contrast dose reduction and elimination in MRI imaging is gaining traction, given the detrimental effects of Gadolinium-based Contrast Agents (GBCAs). These DL algorithms are however limited by the availability of…

Image and Video Processing · Electrical Eng. & Systems 2023-07-25 Dayang Wang , Srivathsa Pasumarthi , Greg Zaharchuk , Ryan Chamberlain

Edge illumination (EI) is a non-interferometric X-ray phase contrast imaging (XPCI) method that has been successfully implemented with conventional polychromatic sources, thanks to its relaxed coherence requirements. Like other XPCI…

Medical Physics · Physics 2017-09-27 G. K. Kallon , F. A. Vittoria , M. Endrizzi , P. C. Diemoz , C. K. Hagen , A. Zamir , D. Basta , A. Olivo

State-of-the-art pre-trained image models predominantly adopt a two-stage approach: initial unsupervised pre-training on large-scale datasets followed by task-specific fine-tuning using Cross-Entropy loss~(CE). However, it has been…

Computer Vision and Pattern Recognition · Computer Science 2024-11-18 Zijun Long , George Killick , Lipeng Zhuang , Gerardo Aragon-Camarasa , Zaiqiao Meng , Richard Mccreadie

We propose a modification of the improved cross entropy (iCE) method to enhance its performance for network reliability assessment. The iCE method performs a transition from the nominal density to the optimal importance sampling (IS)…

Applications · Statistics 2022-11-18 Jianpeng Chan , Iason Papaioannou , Daniel Straub

Phase-contrast X-ray imaging can improve the visibility of weakly absorbing objects (e.g. soft tissues) by an order of magnitude or more compared to conventional radiographs. Previously, it has been shown that combining phase retrieval with…

Contrast-enhanced imaging is central to oncologic diagnosis, but contrast agents can be contraindicated for many of the patients who need them most. Synthesizing contrast scans from non-contrast inputs is the natural response. Two obstacles…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Yifan Chen , Fei Yin , Hao Chen , Jia Wu , Chao Li
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