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Domain generalization is the problem of machine learning when the training data and the test data come from different data domains. We present a simple theoretical model of learning to generalize across domains in which there is a…

Machine Learning · Computer Science 2020-02-14 Vikas K. Garg , Adam Kalai , Katrina Ligett , Zhiwei Steven Wu

Domain Generalization aims to develop models that can generalize to novel and unseen data distributions. In this work, we study how model architectures and pre-training objectives impact feature richness and propose a method to effectively…

Machine Learning · Computer Science 2025-04-30 Xavier Thomas , Deepti Ghadiyaram

Supervised learning results typically rely on assumptions of i.i.d. data. Unfortunately, those assumptions are commonly violated in practice. In this work, we tackle such problem by focusing on domain generalization: a formalization where…

Machine Learning · Computer Science 2024-10-30 Isabela Albuquerque , João Monteiro , Mohammad Darvishi , Tiago H. Falk , Ioannis Mitliagkas

We present MaskGen, a theoretically grounded and deliberately simple approach for domain generalization in 3D biomedical image segmentation. Modern segmentation models degrade sharply under shifts in modality, disease severity, clinical…

Image and Video Processing · Electrical Eng. & Systems 2026-05-12 Sebo Diaz , Polina Golland , Elfar Adalsteinsson , Neel Dey

The performance of predictive models in clinical settings often degrades when deployed in new hospitals due to distribution shifts. This paper presents a large-scale study of causality-inspired domain generalization on heterogeneous…

Applications · Statistics 2026-03-03 Malte Londschien , Manuel Burger , Gunnar Rätsch , Peter Bühlmann

Domain generalization typically requires data from multiple source domains for model learning. However, such strong assumption may not always hold in practice, especially in medical field where the data sharing is highly concerned and…

Computer Vision and Pattern Recognition · Computer Science 2022-06-30 Quande Liu , Cheng Chen , Qi Dou , Pheng-Ann Heng

Computer-aided detection systems based on deep learning have shown great potential in breast cancer detection. However, the lack of domain generalization of artificial neural networks is an important obstacle to their deployment in changing…

Image and Video Processing · Electrical Eng. & Systems 2023-01-25 Lidia Garrucho , Kaisar Kushibar , Socayna Jouide , Oliver Diaz , Laura Igual , Karim Lekadir

Modern deep neural networks suffer from performance degradation when evaluated on testing data under different distributions from training data. Domain generalization aims at tackling this problem by learning transferable knowledge from…

Computer Vision and Pattern Recognition · Computer Science 2021-05-25 Qinwei Xu , Ruipeng Zhang , Ya Zhang , Yanfeng Wang , Qi Tian

Behavior cloning has shown promise for robot manipulation, but real-world demonstrations are costly to acquire at scale. While simulated data offers a scalable alternative, particularly with advances in automated demonstration generation,…

Robotics · Computer Science 2026-01-19 Shuo Cheng , Liqian Ma , Zhenyang Chen , Ajay Mandlekar , Caelan Garrett , Danfei Xu

Domain generalization algorithms use training data from multiple domains to learn models that generalize well to unseen domains. While recently proposed benchmarks demonstrate that most of the existing algorithms do not outperform simple…

Machine Learning · Computer Science 2021-11-30 Tigran Galstyan , Hrayr Harutyunyan , Hrant Khachatrian , Greg Ver Steeg , Aram Galstyan

Temporal domain generalization is a promising yet extremely challenging area where the goal is to learn models under temporally changing data distributions and generalize to unseen data distributions following the trends of the change. The…

Machine Learning · Computer Science 2023-02-13 Guangji Bai , Chen Ling , Liang Zhao

Domain randomization is a popular technique for improving domain transfer, often used in a zero-shot setting when the target domain is unknown or cannot easily be used for training. In this work, we empirically examine the effects of domain…

Machine Learning · Computer Science 2019-07-12 Bhairav Mehta , Manfred Diaz , Florian Golemo , Christopher J. Pal , Liam Paull

Machine learning models trained with purely observational data and the principle of empirical risk minimization \citep{vapnik_principles_1992} can fail to generalize to unseen domains. In this paper, we focus on the case where the problem…

Machine Learning · Statistics 2020-10-27 Maximilian Ilse , Jakub M. Tomczak , Patrick Forré

Deep learning models usually suffer from domain shift issues, where models trained on one source domain do not generalize well to other unseen domains. In this work, we investigate the single-source domain generalization problem: training a…

Computer Vision and Pattern Recognition · Computer Science 2023-04-24 Cheng Ouyang , Chen Chen , Surui Li , Zeju Li , Chen Qin , Wenjia Bai , Daniel Rueckert

Deep Learning has thrived on the emergence of biomedical big data. However, medical datasets acquired at different institutions have inherent bias caused by various confounding factors such as operation policies, machine protocols,…

Image and Video Processing · Electrical Eng. & Systems 2019-11-15 Yundong Zhang , Hang Wu , Huiye Liu , Li Tong , May D Wang

Geographic distribution shift arises when the distribution of locations on Earth in a training dataset is different from what is seen at inference time. Using standard empirical risk minimization (ERM) in this setting can lead to uneven…

Machine Learning · Computer Science 2026-02-10 Ruth Crasto , Esther Rolf

The problem of domain generalization concerns learning predictive models that are robust to distribution shifts when deployed in new, previously unseen environments. Existing methods typically require labeled data from multiple training…

When machine learning models are deployed on a test distribution different from the training distribution, they can perform poorly, but overestimate their performance. In this work, we aim to better estimate a model's performance under…

Machine Learning · Computer Science 2020-07-08 Ching-Yao Chuang , Antonio Torralba , Stefanie Jegelka

Existing calibration algorithms address the problem of covariate shift via unsupervised domain adaptation. However, these methods suffer from the following limitations: 1) they require unlabeled data from the target domain, which may not be…

Machine Learning · Computer Science 2021-10-19 Yunye Gong , Xiao Lin , Yi Yao , Thomas G. Dietterich , Ajay Divakaran , Melinda Gervasio

ML models deployed in production often have to face unknown domain changes, fundamentally different from their training settings. Performance prediction models carry out the crucial task of measuring the impact of these changes on model…

Machine Learning · Computer Science 2022-06-23 Simona Maggio , Victor Bouvier , Léo Dreyfus-Schmidt