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Large-volume optical coherence tomography (OCT)-setups employ scanning mirrors and suffer from non-linear geometric distortion artifacts in which the degree of distortion is determined by the maximum angles over which the mirrors rotate. In…
Optical coherence tomography (OCT) is a 3D imaging technique that was introduced in 1991 [Science 254, 1178 (1991); Applied Optics 31, 919 (1992)]. Since 2018 there has been growing interest in a new type of OCT scheme based on the use of…
In vivo application of dynamic optical coherence tomography (DOCT) is hindered by bulk motion of the sample. We demonstrate DOCT imaging of \invivo human skin by adopting a sample-fixation attachment to suppress bulk motion and a subsequent…
Phase sensitive detection in spectral domain optical coherence tomography (SD-OCT) is a powerful method for functional imaging of biological events with high spatiotemporal resolution. The depth-dependent signal-to-noise ratio (SNR) is a…
Optical Coherence Tomography (OCT) is a non-invasive depth resolved optical imaging modality, that enables high resolution, cross-sectional imaging in biological tissues and materials at clinically relevant depths. Though OCT offers high…
Dispersion is a common phenomenon in optics due to the frequency dependence of the refractive index in polychromatic light. This issue, if left untreated in optical coherence tomography (OCT) imaging, leads to signal broadening of the…
Acousto-Optical Coherence Tomography (AOCT) is variant of Acousto Optic Imaging (called also ultrasonic modulation imaging) that makes possible to get z resolution with acoustic and optic Continuous Wave (CW) beams. We describe here…
Medical image segmentation has played an important role in medical analysis and widely developed for many clinical applications. Deep learning-based approaches have achieved high performance in semantic segmentation but they are limited to…
As a non-invasive imaging modality, optical coherence tomography (OCT) can provide micrometer-resolution 3D images of retinal structures. Therefore it is commonly used in the diagnosis of retinal diseases associated with edema in and under…
In this paper, we propose a new framework for segmenting feature-based moving objects under affine subspace model. Since the feature trajectories in practice are high-dimensional and contain a lot of noise, we firstly apply the sparse PCA…
Holographic optical coherence tomography (OCT) is a powerful imaging technique, but its ability to reveal low-reflectivity features is limited. In this study, we performed holographic OCT by incoherently averaging volumes with changing…
Optical Coherence Tomography (OCT) imaging is pivotal in diagnosing ophthalmic conditions by providing detailed cross-sectional images of the anterior and posterior segments of the eye. Nonetheless, speckle noise and other imaging artifacts…
Inverse scattering in optical coherence tomography (OCT) seeks to recover both structural images and intrinsic tissue optical properties, including refractive index, scattering coefficient, and anisotropy. This inverse problem is…
This work addresses the critical problem of tracking fast-moving objects through strongly scattering media in a low-light environment. Different from existing approaches that use frame-based cameras with fixed exposure times, which trade…
A photonic force microscope comprises of an optically trapped micro-probe and a position detection system to track the motion of the probe. Signal collection for motion detection is often carried out using the backscattered light off the…
We demonstrate in vivo endoscopic optical coherence tomography (OCT) imaging in the forward direction using a flexible fiber bundle. In comparison to current conventional forward looking probe schemes, our approach simplifies the endoscope…
Mechanical properties of tissue provide valuable information for identifying lesions. One approach to obtain quantitative estimates of elastic properties is shear wave elastography with optical coherence elastography (OCE). However, given…
Marker-based Optical Motion Capture (OMC) paired with biomechanical modeling is currently considered the most precise and accurate method for measuring human movement kinematics. However, combining differentiable biomechanical modeling with…
Optical tomographic cross-sectional images of biological samples were made possible by interferometric imaging techniques such as Optical Coherence Tomography (OCT). Owing to its unprecedented view of the sample, OCT has become a gold…
Optical coherence tomography angiography (OCTA) is a novel and clinically promising imaging modality to image retinal and sub-retinal vasculature. Based on repeated optical coherence tomography (OCT) scans, intensity changes are observed…