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Optical fluorescence imaging is capable of measuring both the spatial and rotational dynamics of single molecules. However, unavoidable measurement noise will result in inaccurate estimates of rotational dynamics, causing a molecule to…

Optics · Physics 2019-05-22 Oumeng Zhang , Matthew D. Lew

We consider the motion of red blood cells and other non-spherical microcapsules dilutely suspended in a simple shear flow. Our analysis indicates that depending on the viscosity, membrane elasticity, geometry and shear rate, the particle…

Soft Condensed Matter · Physics 2015-06-25 J. M. Skotheim , T. W. Secomb

The multi-cellular hydrodynamic interactions play a critical role in the phenomenology of blood flow in the microcirculation. A fast algorithm has been developed to simulate large numbers of cells modeled as elastic thin membranes. For red…

Fluid Dynamics · Physics 2008-10-14 Amir H. G. Isfahani , Hong Zhao , Jonathan B. Freund

Integrating optical diffraction tomography with imaging flow cytometry enables label-free quantifications of the three-dimensional (3D) morphology and hemoglobin content of red blood cells (RBCs) in their natural form. Self-rotation of RBCs…

Medical Physics · Physics 2023-09-28 Yu-Hsiang Chang , Yang-Hsien Lin , Kung-Bin Sung

Viscosity is a key property of cell membranes that controls mobility of embedded proteins and membrane remodeling. Measuring it is challenging because existing approaches involve complex experimental designs and/or models, and the…

Soft Condensed Matter · Physics 2023-07-19 Hammad A. Faizi , Rumiana Dimova , Petia M. Vlahovska

The rheological characterisation of complex fluids is mostly performed under simple shear flow in rotational rheometers. Their modern commercial versions are extremely sensitive instruments which are able to provide very accurate…

Fluid Dynamics · Physics 2021-03-05 Ahmad Fakhari , Francisco J. Galindo-Rosales

Red blood cells (RBCs) sustain mechanical stresses associated with microcirculatory flow through ATP-driven plasma membrane flickering. This is an active phenomenon driven by motor proteins that regulate interactions between the spectrin…

In-situ characterization of minute amounts of complex fluids is a challenge. Magnetic Rotational Spectroscopy (MRS) with submicron probes offers flexibility and accuracy providing desired spatial and temporal resolution in characterization…

Materials Science · Physics 2015-03-19 Konstantin G. Kornev , Yu Gu , Pavel Aprelev , Alexander Tokarev

The dynamics of red blood cells (RBCs) in simple shear flow was studied using a theoretical approach based on three variables: a shape parameter, the inclination angle $\theta$, and phase angle $\phi$ of the membrane rotation. At high shear…

Soft Condensed Matter · Physics 2009-08-07 Hiroshi Noguchi

Vascular remodelling is inherent to the pathogenesis of many diseases including cancer, neurodegeneration, fibrosis, hypertension, and diabetes. In this paper, a new susceptibility-contrast based MRI approach is established to analyse…

Asteroseismology allows us to probe stellar interiors. Mixed modes can be used to probe the physical conditions in red giant cores. However, we still need to identify the physical mechanisms that transport angular momentum inside red…

Solar and Stellar Astrophysics · Physics 2018-08-08 C. Gehan , B. Mosser , E. Michel , R. Samadi , T. Kallinger

The functions and elasticities of the cell are largely related to the structures of the cytoskeletons underlying the lipid bi-layer. Among various cell types, the Red Blood Cell (RBC) possesses a relatively simple cytoskeletal structure.…

Biological Physics · Physics 2016-01-20 Lipeng Lai , Xiaofeng Xu , Chwee Teck Lim , Jianshu Cao

We experimentally demonstrate that the rotation of molecules embedded in helium nanodroplets can be controlled with an optical centrifuge, allowing for the study of molecular dynamics inside the strongly interacting many-body environment of…

Quantum Physics · Physics 2025-11-11 Ian MacPhail-Bartley , Alexander A. Milner , Frank Stienkemeier , Valery Milner

Sorting cells based on their intrinsic properties is a highly desirable objective, since changes in cell deformability are often associated with various stress conditions and diseases. Deterministic lateral displacement (DLD) devices offer…

Fluid Dynamics · Physics 2024-06-03 Zunmin Zhang , Wei Chien , Ewan Henry , Dmitry A. Fedosov , Gerhard Gompper

We present a numerical analysis of the lateral movement and equilibrium radial positions of red blood cells (RBCs) with major diameter of 8 $\mu$m under a Newtonian fluid in a circular channel with 50-$\mu$m diameter. Each RBC, modelled as…

We present a numerical analysis of the rheology of a suspension of red blood cells (RBCs) in a wall-bounded shear flow. The flow is assumed as almost inertialess. The suspension of RBCs, modeled as biconcave capsules whose membrane follows…

Fluid Dynamics · Physics 2019-07-24 Naoki Takeishi , Marco E. Rosti , Yohsuke Imai , Shigeo Wada , Luca Brandt

The flow behavior of blood in microvessels is directly associated with tissue perfusion and oxygen delivery. Current efforts on modeling blood flow have primarily focused on the flow properties of blood with red blood cells (RBCs) having a…

Soft Condensed Matter · Physics 2024-06-03 Wei Chien , Gerhard Gompper , Dmitry A. Fedosov

We propose a novel method for measuring linear and non-linear viscoelastic properties of a liquid by the oscillatory motion of an immersed rotating body in a vessel. The shape of a rotating object is general and we tested four different…

Fluid Dynamics · Physics 2025-05-19 Hye Jin Ahn , Wook Ryol Hwang

This study numerically and analytically investigates the dynamics of a rotor under viscous or dry friction as a non-equilibrium probe of a granular gas. In order to demonstrate the role of the rotor as a probe for a non-equilibrium bath,…

Statistical Mechanics · Physics 2016-10-04 Tomohiko G. Sano , Kiyoshi Kanazawa , Hisao Hayakawa

Rotational dynamics often challenge physical intuition while enabling unique realizations, from the rotor of a gyroscope that maintains its orientation regardless of the outer gimbals, to a tennis racket that rotates around its handle when…