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In clinical studies with paired organs, binary outcomes often exhibit intra-subject correlation and may include a mixture of unilateral and bilateral observations. Under Donner's constant correlation model, we develop three likelihood-based…

Methodology · Statistics 2025-10-22 Jia Zhou , Chang-Xing Ma

We consider the problem of estimating and inferring treatment effects in randomized experiments. In practice, stratified randomization, or more generally, covariate-adaptive randomization, is routinely used in the design stage to balance…

Methodology · Statistics 2022-09-27 Hanzhong Liu , Fuyi Tu , Wei Ma

A popular technique for selecting and tuning machine learning estimators is cross-validation. Cross-validation evaluates overall model fit, usually in terms of predictive accuracy. In causal inference, the optimal choice of estimator…

Methodology · Statistics 2021-07-07 Dominik Rothenhäusler

We provide a principled way for investigators to analyze randomized experiments when the number of covariates is large. Investigators often use linear multivariate regression to analyze randomized experiments instead of simply reporting the…

Statistics Theory · Mathematics 2022-06-08 Adam Bloniarz , Hanzhong Liu , Cun-Hui Zhang , Jasjeet Sekhon , Bin Yu

Generalized linear models, such as logistic regression, are widely used to model the association between a treatment and a binary outcome as a function of baseline covariates. However, the coefficients of a logistic regression model…

Methodology · Statistics 2022-01-04 Jiaqi Yin , Sonia Markes , Thomas S. Richardson , Linbo Wang

This work studies the statistical properties of the maximum penalized likelihood approach in a semi-parametric framework. We recall the penalized likelihood approach for estimating a function and review some asymptotic results. We…

Statistics Theory · Mathematics 2014-01-31 Daniel Commenges , Jérémie Bureau , Hein Putter

This paper proposes improved methods for the maximum likelihood (ML) estimation of the equivalent number of looks $L$. This parameter has a meaningful interpretation in the context of polarimetric synthetic aperture radar (PolSAR) images.…

Computer Vision and Pattern Recognition · Computer Science 2014-04-22 Abraão D. C. Nascimento , Alejandro C. Frery , Renato J. Cintra

A significant hurdle for analyzing large sample data is the lack of effective statistical computing and inference methods. An emerging powerful approach for analyzing large sample data is subsampling, by which one takes a random subsample…

Methodology · Statistics 2015-11-24 Rong Zhu , Ping Ma , Michael W. Mahoney , Bin Yu

We study exact confidence intervals and two-sided hypothesis tests for univariate parameters of stochastically increasing discrete distributions, such as the binomial and Poisson distributions. It is shown that several popular methods for…

Statistics Theory · Mathematics 2016-10-03 MÅns Thulin , Silvelyn Zwanzig

Confidence interval (CI) methods for stratified bilateral studies use intraclass correlation to avoid misleading results. In this article, we propose four CI methods (sample-size weighted global MLE-based Wald-type CI, complete MLE-based…

Methodology · Statistics 2023-03-27 Wanqing Tian , Chang-Xing Ma

Most cluster randomized trials (CRTs) randomize fewer than 30-40 clusters in total. When performing inference for such ``small'' CRTs, it is important to use methods that appropriately account for the small sample size. When the generalized…

Methodology · Statistics 2025-12-01 Shifeng Sun , Xueqi Wang , Zhuoran Hou , Elizabeth L. Turner

We propose a penalized likelihood method to fit the bivariate categorical response regression model. Our method allows practitioners to estimate which predictors are irrelevant, which predictors only affect the marginal distributions of the…

Methodology · Statistics 2022-01-25 Aaron J. Molstad , Adam J. Rothman

Latent variable models (LVMs) are commonly used in psychology and increasingly used for analyzing brain imaging data. Such studies typically involve a small number of participants (n<100), where standard asymptotic results often fail to…

Methodology · Statistics 2020-06-15 Brice Ozenne , Patrick M. Fisher , Esben Budtz-Jørgensen

High-dimensional regression models with regularized sparse estimation are widely applied. For statistical inferences, debiased methods are available about single coefficients or predictions with sparse new covariate vectors (also called…

Statistics Theory · Mathematics 2025-07-16 Libin Liang , Zhiqiang Tan

We propose new model selection criteria based on generalized ridge estimators dominating the maximum likelihood estimator under the squared risk and the Kullback-Leibler risk in multivariate linear regression. Our model selection criteria…

Statistics Theory · Mathematics 2016-04-08 Yuichi Mori , Taiji Suzuki

The points at which the log likelihood falls by 1/2 from its maximum value are often used to give the `errors' on a result, i.e. the 68% central confidence interval. The validity of this is examined for two simple cases: a lifetime…

Data Analysis, Statistics and Probability · Physics 2007-05-23 Roger Barlow

We consider estimation and inference on average treatment effects under unconfoundedness conditional on the realizations of the treatment variable and covariates. Given nonparametric smoothness and/or shape restrictions on the conditional…

Applications · Statistics 2022-10-04 Timothy B. Armstrong , Michal Kolesár

Model averaging methods have become an increasingly popular tool for improving predictions and dealing with model uncertainty, especially in Bayesian settings. Recently, frequentist model averaging methods such as information theoretic and…

Econometrics · Economics 2024-04-18 Kevin Huynh

When presenting forensic evidence, such as a DNA match, experts often use the Likelihood ratio (LR) to explain the impact of evidence . The LR measures the probative value of the evidence with respect to a single hypothesis such as 'DNA…

Applications · Statistics 2021-06-11 Norman Fenton , Martin Neil

We present improved numerical approximations to the exact Poissonian confidence limits for small numbers n of observed events following the approach of Gehrels (1986). Analytic descriptions of all parameters used in the approximations are…

Astrophysics · Physics 2009-11-07 Harald Ebeling
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