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We present a tomographic imaging technique, termed Deep Prior Diffraction Tomography (DP-DT), to reconstruct the 3D refractive index (RI) of thick biological samples at high resolution from a sequence of low-resolution images collected…
X-ray computed tomographic infrastructures are medical imaging modalities that rely on the acquisition of rays crossing examined objects while measuring their intensity decrease. Physical measurements are post-processed by mathematical…
During spinal fusion surgery, screws are placed close to critical nerves suggesting the need for highly accurate screw placement. Verifying screw placement on high-quality tomographic imaging is essential. C-arm Cone-beam CT (CBCT) provides…
Numerous dual-energy CT (DECT) techniques have been developed in the past few decades. Dual-energy CT (DECT) statistical iterative reconstruction (SIR) has demonstrated its potential for reducing noise and increasing accuracy. Our lab…
Computed tomography (CT) is widely used in screening, diagnosis, and image-guided therapy for both clinical and research purposes. Since CT involves ionizing radiation, an overarching thrust of related technical research is development of…
In computed tomography (CT), the forward model consists of a linear Radon transform followed by an exponential nonlinearity based on the attenuation of light according to the Beer-Lambert Law. Conventional reconstruction often involves…
Phase retrieval, or the process of recovering phase information in reciprocal space to reconstruct images from measured intensity alone, is the underlying basis to a variety of imaging applications including coherent diffraction imaging…
Large Vision Model (LVM) has recently demonstrated great potential for medical imaging tasks, potentially enabling image enhancement for sparse-view Cone-Beam Computed Tomography (CBCT), despite requiring a substantial amount of data for…
We study iterative signal reconstruction in computed tomography (CT), wherein measurements are produced by a linear transformation of the unknown signal followed by an exponential nonlinear map. Approaches based on pre-processing the data…
Commercial iterative reconstruction techniques on modern CT scanners target radiation dose reduction but there are lingering concerns over their impact on image appearance and low contrast detectability. Recently, machine learning,…
Poor tissue visualization and quantitative accuracy in CBCT is a major barrier in expanding the role of CBCT imaging from target localization to quantitative treatment monitoring and plan adaptations in radiation therapy sessions. To…
Background: Cone-beam computed tomography (CBCT) scans, performed fractionally (e.g., daily or weekly), are widely utilized for patient alignment in the image-guided radiotherapy (IGRT) process, thereby making it a potential imaging…
In radiation therapy (RT), the reliance on pre-treatment computed tomography (CT) images encounter challenges due to anatomical changes, necessitating adaptive planning. Daily cone-beam CT (CBCT) imaging, pivotal for therapy adjustment,…
Deep learning methods for accelerated MRI achieve state-of-the-art results but largely ignore additional speedups possible with noncartesian sampling trajectories. To address this gap, we created a generative diffusion model-based…
Inverse problems exist in many domains such as phase imaging, image processing, and computer vision. These problems are often solved with application-specific algorithms, even though their nature remains the same: mapping input image(s) to…
Dual-energy computed tomography (DECT) has been widely used in many applications that need material decomposition. Image-domain methods directly decompose material images from high- and low-energy attenuation images, and thus, are…
Low Dose Computed Tomography suffers from a high amount of noise and/or undersampling artefacts in the reconstructed image. In the current article, a Deep Learning technique is exploited as a regularization term for the iterative…
While model-based reconstruction methods have been successfully applied to flat-panel cone-beam CT (FP-CBCT) systems, typical implementations ignore both spatial correlations in the projection data as well as system blurs due to the…
We propose a method for the computation of a consistent system matrix for two- and three-dimensional cone-beam computed tomography (CT). The method relies on the decomposition of the cone-voxel intersection volumes into subvolumes that…
Model-based iterative reconstruction (MBIR) techniques have demonstrated many advantages in X-ray CT image reconstruction. The MBIR approach is often modeled as a convex optimization problem including a data fitting function and a penalty…