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We derive the optimal estimates of the free energies of an arbitrary number of thermodynamic states from nonequilibrium work measurements; the work data are collected from forward and reverse switching processes and obey a fluctuation…

Statistical Mechanics · Physics 2009-11-11 Paul Maragakis , Martin Spichty , Martin Karplus

We have experimentally checked the Jarzynski equality and the Crooks relation on the thermal fluctuations of a macroscopic mechanical oscillator in contact with a heat reservoir. We found that, independently of the time scale and amplitude…

Statistical Mechanics · Physics 2009-11-11 F. Douarche , S. Ciliberto , A. Petrosyan , I. Rabbiosi

Quantum thermodynamics allows for the interconversion of quantum coherence and mechanical work. Quantum coherence is thus a potential physical resource for quantum machines. However, formulating a general nonequilibrium thermodynamics of…

Quantum Physics · Physics 2025-11-05 Franklin L. S. Rodrigues , Eric Lutz

The Jarzynski equality (JE) provides a nonequilibrium method to measure and calculate the free energy difference (FED). Note that if two systems share the same Hamiltonian at two equilibrium states, respectively, they share the same FED…

Statistical Mechanics · Physics 2020-07-16 Liyun Zhu , Jiao Wang

The non-equilibrium dynamics of quantum many-body systems is one of the most fascinating problems in physics. Open questions range from how they relax to equilibrium to how to extract useful work from them. A critical point lies in…

Quantum Physics · Physics 2018-05-23 J. Mur-Petit , A. Relaño , R. A. Molina , D. Jaksch

In recent years a quantum information theoretic framework has emerged for incorporating non-classical phenomena into fluctuation relations. Here we elucidate this framework by exploring deviations from classical fluctuation relations…

Quantum Physics · Physics 2021-12-09 Zoe Holmes , Erick Hinds Mingo , Calvin Y. -R. Chen , Florian Mintert

A fluctuation relation, which is an extended form of the Jarzynski equality, is introduced and discussed. We show how to apply this relation in order to evaluate the free energy landscape of simple systems. These systems are manipulated by…

Statistical Mechanics · Physics 2007-05-23 A. Imparato , L. Peliti

The computation of free energy differences through an exponential weighting of out of equilibrium paths (known as the Jarzynski equality) is often used for transitions between states described by an external parameter $\lambda$ in the…

Statistical Mechanics · Physics 2015-06-25 Tony Lelievre , Mathias Rousset , Gabriel Stoltz

The Jarzynski equality (JE), which relates works of non-equilibrium trajectories to the free energy difference of the initial and final states of the non-equilibrium process, provides an efficient way to calculate free energies of systems…

Soft Condensed Matter · Physics 2016-04-20 Biao Wan , Cheng Yang , Yanting Wang , Xin Zhou

We show a practical application of an well-known nonequilibrium relation, the Jarzynski equality, in quantum computation. Its implementation may open a way to solve combinatorial optimization problems, minimization of a real single-valued…

Quantum Physics · Physics 2010-07-06 Masayuki Ohzeki , Hidetoshi Nishimori

A quantum fluctuation theorem for a driven quantum subsystem interacting with its environment is derived based solely on the assumption that its reduced density matrix obeys a closed evolution equation i.e. a quantum master equation (QME).…

Statistical Mechanics · Physics 2010-03-01 Massimiliano Esposito , Shaul Mukamel

Calculating free energy differences is a topic of substantial interest and has many applications including molecular docking and hydration, solvation, and binding free energies which is used in computational drug discovery. However, in…

Chemical Physics · Physics 2013-10-16 Asaf Farhi

In this paper we give a pedagogical introduction to the ideas of quantum thermodynamics and work fluctuations, using only basic concepts from quantum and statistical mechanics. After reviewing the concept of work, as usually taught in…

Quantum Physics · Physics 2018-05-03 Wellington L. Ribeiro , Gabriel T. Landi , Fernando Semião

Free energy calculations are at the heart of physics-based analyses of biochemical processes. They allow us to quantify molecular recognition mechanisms, which determine a wide range of biological phenomena from how cells send and receive…

A promising method for calculating free energy differences Delta F is to generate non-equilibrium data via ``fast-growth'' simulations or experiments -- and then use Jarzynski's equality. However, a difficulty with using Jarzynski's…

Computational Physics · Physics 2007-05-23 F. Marty Ytreberg , Daniel M. Zuckerman

Of indisputable relevance for non-equilibrium thermodynamics, fluctuations theorems have been generalized to the framework of quantum thermodynamics, with the notion of work playing a key role in such contexts. The typical approach consists…

Quantum Physics · Physics 2023-06-28 Thales Augusto Barbosa Pinto Silva , Renato Moreira Angelo

We experimentally verify the Jarzynski and W\"ojcik quantum heat exchange fluctuation relation by implementing the interferometric technique in liquid-state Nuclear Magnetic Resonance setup and study the exchange heat statistics between two…

Statistical Mechanics · Physics 2019-10-30 Soham Pal , T S Mahesh , Bijay Kumar Agarwalla

This article traces the development of fluctuation theory and its deep connection to irreversibility, from equilibrium to near-equilibrium, and finally to far-from-equilibrium systems. Classical fluctuation theorems, which capture the…

Quantum Physics · Physics 2025-12-30 Sounak Bandyopadhyay , Arnab Ghosh

We study the statistics of energy fluctuations in a three-level quantum system subject to a sequence of projective quantum measurements. We check that, as expected, the quantum Jarzynski equality holds provided that the initial state is…

Quantum Physics · Physics 2020-03-25 Guido Giachetti , Stefano Gherardini , Andrea Trombettoni , Stefano Ruffo

We discuss the role of quantum coherence in the energy fluctuations of open quantum systems. To this aim, we introduce a protocol, to which we refer to as the end-point-measurement scheme, allowing to define the statistics of energy changes…

Quantum Physics · Physics 2022-04-13 S. Gherardini , A. Belenchia , M. Paternostro , A. Trombettoni